Cystatin E/M (CST6) ELISA试剂盒

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. 再加上,我们可以发CST6 抗体 (90)CST6 蛋白 (16)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
CST6 1474 Q15828
小鼠 CST6 CST6 73720  
大鼠 CST6 CST6 171096  
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0.053 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 15至17个工作日
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适于 CST6 相互作用对的更多 ELISA 试剂盒

Human Cystatin E/M (CST6) interaction partners

  1. Data suggest that melanoma cells internalize/absorb cystatin C (显示 CST3 ELISA试剂盒) from culture media, leading to increased intracellular cystatin C (显示 CST3 ELISA试剂盒) levels; cystatin E/M is internalized as well but at modest rate due to down-regulation of cell migration; however, the effect of intracellular cystatin E/M on down-regulation of legumain (显示 LGMN ELISA试剂盒) activity is pronounced.

  2. Results provide evidence that cystatin E/M is a tumor suppressor gene which plays an important role in the regulation of NF-kappaB (显示 NFKB1 ELISA试剂盒).

  3. Low CST6 expression is associated with breast cancer.

  4. Developed a Methylation-Sensitive High Resolution Melting Analysis (MS-HRMA) assay for the investigation of CST6 promoter methylation in breast cancer patients.CST6 promoter was methylated in 39/80 of FFPEs.

  5. The CST6 promoter is highly methylated in circulating cell-free DNA of breast cancer patients, but not in healthy individuals.

  6. Data show a regulatory role of cystatin E/M in controlling both intra- and extracellular legumain (显示 LGMN ELISA试剂盒) activity.

  7. The ectopic expression of CST6 in cancer cells rescued mice from overt osteolytic metastasis and deaths in the animal study, while CST6 knockdown markedly enhanced cancer cell bone metastasis and shortened animal survival.

  8. An association between the quantity of CST6 methylation and the expression statuses of estrogen receptor (显示 ESR1 ELISA试剂盒), progesterone receptor (显示 PGR ELISA试剂盒), and HER4 (显示 ERBB4 ELISA试剂盒) in tumor tissues was found

  9. the level of cystatin E/M regulates legumain (显示 LGMN ELISA试剂盒) activity and hence the invasive potential of human melanoma cells

  10. CST6 is not a major gene contributing to type 1 and 2 harlequin ichthyosis

Mouse (Murine) Cystatin E/M (CST6) interaction partners

  1. Using quenched activity-based probes, we identified mouse cathepsin B (CtsB (显示 CTSB ELISA试剂盒)), which is expressed in the lower regions of the hair follicle, as an additional target of mouse Cst6

  2. conclude that a tightly regulated balance between cathepsin L (显示 CTSL1 ELISA试剂盒) and cystatin M/E is essential for tissue integrity in epidermis, hair follicles, and corneal epithelium

  3. cystatin M/E has a role in skin barrier formation and a potential role as a tumor suppressor gene [review]

CST6 抗原简介

Antigen Summary

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.

Gene names and symbols associated with Cystatin E/M (CST6) ELISA试剂盒

  • cystatin E/M (CST6) 抗体
  • cystatin E/M (Cst6) 抗体
  • 1110017E11Rik 抗体
  • CST6 抗体
  • ichq 抗体
  • N28197 抗体

Protein level used designations for Cystatin E/M (CST6) ELISA试剂盒

cystatin E/M , cystatin M , cystatin-M , cystatin 6 , cystatin M/E , cystatin-6 , cystatin-E , cysteine proteinase inhibitor , harlequin ichthyosis , harlequin ichthysosis , cystatin N

GENE ID SPECIES
466668 Pan troglodytes
503685 Bos taurus
714999 Macaca mulatta
1474 Homo sapiens
483719 Canis lupus familiaris
73720 Mus musculus
171096 Rattus norvegicus
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