Cullin 4B (CUL4B) ELISA试剂盒

CUL4B is a member of the cullin family. 再加上,我们可以发Cullin 4B 抗体 (95)Cullin 4B 蛋白 (4)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
 CUL4B CUL4B 8450 Q13620
小鼠 CUL4B CUL4B 72584 A2A432
大鼠 CUL4B CUL4B 302502  
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适于 Cullin 4B 相互作用对的更多 ELISA 试剂盒

Zebrafish Cullin 4B (CUL4B) interaction partners

  1. Results show that cul4a (显示 CUL4A ELISA试剂盒) but not cul4b is required for the expression of tbx5a, an essential transcription factor in heart and limb development.

Human Cullin 4B (CUL4B) interaction partners

  1. The CUL4B interacts with WD-40 proteins through the adaptor protein DNA damage-binding protein 1 (DDB1) to target substrates for ubiquitylation.

  2. This study found that microRNA-194 (miR (显示 MLXIP ELISA试剂盒)-194) and CUL4B protein were inversely correlated in cancer specimens and demonstrated that miR (显示 MLXIP ELISA试剂盒)-194 could downregulate CUL4B by directly targeting its 3'-UTR (显示 UTS2R ELISA试剂盒).

  3. findings revealed that CUL4A (显示 CUL4A ELISA试剂盒) and CUL4B are differentially associated with etiologic factors for pulmonary malignancies and are independent prognostic markers for the survival of distinct lung cancer subtypes

  4. CUL4B regulates protein turnover and homeostasis in response to dopamine stimulation.

  5. CUL4B protein levels in human subcutaneous adipose tissue is negatively correlated with body mass index.

  6. these results suggest that knockdown of CUL4B inhibited the proliferation and invasion through suppressing the Wnt (显示 WNT2 ELISA试剂盒)/beta-catenin (显示 CTNNB1 ELISA试剂盒) signaling pathway in NSCLC cells. Therefore, CUL4B may represent a novel therapeutic target for the treatment of NSCLC.

  7. these results showed that knockdown of CUL4B inhibit proliferation and promotes apoptosis of colorectal cancer cells through suppressing the Wnt (显示 WNT2 ELISA试剂盒)/beta-catenin (显示 CTNNB1 ELISA试剂盒) signaling pathway

  8. Our data are consistent with the idea that the CUL4A (显示 CUL4A ELISA试剂盒)/B-DDB1-CRBN (显示 CRBN ELISA试剂盒) complex catalyses the polyubiquitination and thus controls the degradation of CLC-1 (显示 CLCN1 ELISA试剂盒) channels.

  9. FBXO44-mediated degradation of RGS2 protein uniquely depends on a Cul4B/DDB1 complex.

  10. results established a critical role of CUL4B in negatively regulating the p53 (显示 TP53 ELISA试剂盒)-ROS (显示 ROS1 ELISA试剂盒) positive feedback loop that drives cellular senescence

Mouse (Murine) Cullin 4B (CUL4B) interaction partners

  1. A cullin 4B-RING E3 ligase complex fine-tunes pancreatic delta cell paracrine interactions

  2. Adipocyte-specific Cul4b knockout (AKO) mice being fed a high-fat diet exhibited increased body fat accumulation that was mediated by increased adipogenesis. However, AKO mice showed improved metabolic phenotypes, including increased insulin (显示 INS ELISA试剂盒) sensitivity and glucose tolerance. Correspondingly, there was a decreased inflammatory response in adipose tissues of AKO mice.

  3. CUL4B as a key regulator of post-meiotic sperm morphogenesis

  4. CUL4B links two distinct spermatogenetic processes to a single E3 ligase, highlighting the significance of ubiquitin modification during spermatogenesis.

  5. results demonstrate a critical role of CUL4B in hepatocarcinogenesis in mice

  6. Ptgds (显示 PTGDS ELISA试剂盒) is targeted and repressed by the CUL4B/PRC2 complex.

  7. FBXO44-mediated degradation of RGS2 protein uniquely depends on a Cul4B/DDB1 complex.

  8. CUL4B knockdown alleviated in vivo tumorigenesis in glioma xenograft nude mice.

  9. Data indicate a role of cullin family, CUL4B, in the immune system.

  10. Data indicate that in Cul4b-deficient embryonic fibroblasts showed Jab1 (显示 COPS5 ELISA试剂盒) accumulation.

Cullin 4B (CUL4B) 抗原简介

Antigen Summary

This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Cullin 4B (CUL4B) ELISA试剂盒

  • cullin 4B (CUL4B) 抗体
  • cullin 4B S homeolog (cul4b.S) 抗体
  • cullin 4B (Tb927.3.1290) 抗体
  • cullin 4B (cul4b) 抗体
  • cullin 4B (Cul4b) 抗体
  • 2700050M05Rik 抗体
  • AA409770 抗体
  • CUL-4B 抗体
  • im:7140950 抗体
  • im:7150765 抗体
  • MGC115611 抗体
  • mKIAA0695 抗体
  • MRXHF2 抗体
  • MRXS15 抗体
  • MRXSC 抗体
  • RGD1564494 抗体
  • SFM2 抗体
  • Tb03.1J15.620 抗体

Protein level used designations for Cullin 4B (CUL4B) ELISA试剂盒

cullin 4B , cullin-4B , cullin-4B-like , CUL-4B

GENE ID SPECIES
492102 Canis lupus familiaris
539668 Bos taurus
696410 Macaca mulatta
735163 Xenopus laevis
3656065 Trypanosoma brucei brucei strain 927/4 GUTat10.1
100033938 Equus caballus
100079138 Ornithorhynchus anatinus
100151714 Xenopus (Silurana) tropicalis
100194954 Salmo salar
100351102 Oryctolagus cuniculus
100394843 Callithrix jacchus
100475326 Ailuropoda melanoleuca
100542698 Meleagris gallopavo
100564485 Anolis carolinensis
100592746 Nomascus leucogenys
560313 Danio rerio
8450 Homo sapiens
72584 Mus musculus
302502 Rattus norvegicus
422364 Gallus gallus
100513454 Sus scrofa
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