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Crystallin, alpha B ELISA试剂盒

(Crystallin, alpha B (CRYAB))
Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families\; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone\; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits\; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed\; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases\; a missense mutation cosegregated in a family with a desmin-related myopathy. [provided by RefSeq, Jul 2008].
CRYAB ELISA 试剂盒 CRYAB ELISA 试剂盒 CRYAB ELISA 试剂盒 (ABIN6966147)

CRYAB 适用: 小鼠 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate

CRYAB ELISA 试剂盒 CRYAB ELISA 试剂盒 CRYAB ELISA 试剂盒 (ABIN6966146)

CRYAB 适用: 人 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate

CRYAB ELISA 试剂盒 CRYAB ELISA 试剂盒 CRYAB ELISA 试剂盒 (ABIN6955122)

CRYAB 适用: 人 Colorimetric Sandwich ELISA 0.62 ng/mL - 40 ng/mL Cell Lysate, Tissue Homogenate

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Latest Publications for our Crystallin, alpha B ELISA试剂盒

Bolton, Montastier, Carayol, Bonnel, Mir, Marques, Astrup, Saris, Iacovoni, Villa-Vialaneix, Valsesia, Langin, Viguerie: "Molecular Biomarkers for Weight Control in Obese Individuals Subjected to a Multiphase Dietary Intervention." in: The Journal of clinical endocrinology and metabolism, Vol. 102, Issue 8, pp. 2751-2761, (2017) (PubMed).

Baba, Oshitari, Yamamoto: "Level of vitreous alpha-B crystallin in eyes with rhegmatogenous retinal detachment." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 253, Issue 8, pp. 1251-4, (2015) (PubMed).

Aliases for Crystallin, alpha B ELISA试剂盒

crystallin alpha B (CRYAB) ELISA试剂盒
crystallin, alpha B (Cryab) ELISA试剂盒
hypothetical protein (ZK1128.7) ELISA试剂盒
crystallin alpha B (Cryab) ELISA试剂盒
crystallin, alpha B, a (cryaba) ELISA试剂盒
crystallin, alpha B, b (cryabb) ELISA试剂盒
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