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Crystallin, alpha B 蛋白

(Crystallin, alpha B (CRYAB))
Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families\; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone\; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits\; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed\; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases\; a missense mutation cosegregated in a family with a desmin-related myopathy. [provided by RefSeq, Jul 2008].
CRYAB Protein (AA 1-175) (GST tag) CRYAB Protein (AA 1-175) (GST tag) CRYAB Protein (AA 1-175) (GST tag) (ABIN1350424)

CRYAB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

CRYAB Protein (AA 1-175) (His tag) CRYAB Protein (AA 1-175) (His tag) CRYAB Protein (AA 1-175) (His tag) (ABIN3078266)

Crystallography grade CRYAB 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

CRYAB Protein (AA 1-175) (His tag) CRYAB Protein (AA 1-175) (His tag) CRYAB Protein (AA 1-175) (His tag) (ABIN3133386)

Crystallography grade CRYAB 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

Crystallin, alpha B 蛋白 by Grade

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Crystallin, alpha B 蛋白 by Origin

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Crystallin, alpha B 蛋白 by Source

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Crystallin, alpha B 蛋白 by 蛋白类型

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Crystallin, alpha B 蛋白 by 应用范围

Find Crystallin, alpha B 蛋白 validated for a specific application such as ELISA, SDS, WB, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Crystallin, alpha B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350424
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3078266
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133386
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7319198
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7396997
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7396994
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5709329
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2714621
Quantity 20 μg
Datasheet Datasheet
Reactivity Columba livia
Source Yeast
Validations
Cat. No. ABIN1655882
Quantity 1 mg
Datasheet Datasheet
Reactivity Blackbird
Source Yeast
Validations
Cat. No. ABIN1655820
Quantity 1 mg
Datasheet Datasheet
Reactivity Trachemys scripta
Source Yeast
Validations
Cat. No. ABIN1640277
Quantity 1 mg
Datasheet Datasheet
Reactivity Bullfrog
Source Yeast
Validations
Cat. No. ABIN1640274
Quantity 1 mg
Datasheet Datasheet
Reactivity Duck
Source Yeast
Validations
Cat. No. ABIN1609758
Quantity 1 mg
Datasheet Datasheet
Reactivity Chicken
Source Yeast
Validations
Cat. No. ABIN1458765
Quantity 1 mg
Datasheet Datasheet
Reactivity Sheep
Source Yeast
Validations
Cat. No. ABIN1632520
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Crystallin, alpha B 蛋白

Anders, Liu, Mann, Teister, Lauzi, Thanos, Grus, Pfeiffer, Prokosch: "The Small Heat Shock Protein α-Crystallin B Shows Neuroprotective Properties in a Glaucoma Animal Model." in: International journal of molecular sciences, Vol. 18, Issue 11, (2018) (PubMed).

Aliases for Crystallin, alpha B 蛋白

crystallin alpha B (CRYAB) 蛋白
crystallin, alpha B (Cryab) 蛋白
hypothetical protein (ZK1128.7) 蛋白
crystallin alpha B (Cryab) 蛋白
crystallin, alpha B, a (cryaba) 蛋白
crystallin, alpha B, b (cryabb) 蛋白
AACRYA 蛋白
CMD1II 蛋白
Crya-2 蛋白
CRYA2 蛋白
Crya2 蛋白
CRYAB 蛋白
cryab 蛋白
cryab2 蛋白
CTPP2 蛋白
CTRCT16 蛋白
HSPB5 蛋白
HspB5 蛋白
MFM2 蛋白
wu:fe37f08 蛋白
zgc:91937 蛋白
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