Creatine Kinase, Mitochondrial 1, Ubiquitous 蛋白 (CKMT1)

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. 再加上,我们可以发Creatine Kinase, Mitochondrial 1, Ubiquitous 抗体 (18)Creatine Kinase, Mitochondrial 1, Ubiquitous 试剂盒 (5)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
CKMT1 12716 P30275
CKMT1 548596 P12532
大鼠 CKMT1 CKMT1 29593  

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Showing 5 out of 5 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
大肠杆菌(E. Coli) His tag Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1) (AA 40-417), (full length) protein (His tag) 50 μg Log in to see 7至10个工作日
¥1,016.23
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 68至72个工作日
¥136,777.64
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酵母菌 Cow His tag   1 mg Log in to see 24至35个工作日
¥11,489.40
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酵母菌 野猪 His tag   1 mg Log in to see 24至35个工作日
¥11,489.40
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HOST_Yeast (Pichia pastoris) 非结合性   50 μg Log in to see 24至29个工作日
¥4,798.29
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CKMT1 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine)

Human ,

引用最多的Creatine Kinase, Mitochondrial 1, Ubiquitous 蛋白

  1. Human CKMT1 Protein expressed in Escherichia coli (E. coli) - ABIN1046872 : Haas, Korenfeld, Zhang, Perryman, Roman, Strauss: Isolation and characterization of the gene and cDNA encoding human mitochondrial creatine kinase. in The Journal of biological chemistry 1989 (PubMed)

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Mouse (Murine) Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1) interaction partners

  1. Hypothalamic plasticity of neuropeptide Y (显示 NPY 蛋白) is lacking in brain-type creatine kinase double knockout mice with defective thermoregulation

  2. mitochondrial creatine kinase (显示 CKMT2 蛋白) expression in hepatocellular carcinoma may be caused by hepatocarcinogenesis per se but not by loss of mitochondrial integrity, of which ASB9 (显示 ASB9 蛋白) could be a negative regulator

  3. the knock-down of the mitochondrial creatine kinase (显示 CKMT2 蛋白)-1 (CKMT1) by RNA interference causes the dissipation of the mitochondrial membrane potential

  4. UbCKmit was expressed selectively in neurons and localized in their mitochondria in dendrites, cell bodies

  5. Data suggest that amyloid precursor protein (显示 APP 蛋白) may regulate cellular energy levels and mitochondrial function via a direct interaction and stabilization of ubiquitous mitochondrial creatine kinase.

  6. Mt-CK(-/-) on a C57BL/6 background do not develop LV hypertrophy or dysfunction even up to 1 year, and this may be explained by a compensatory increase in MM-CK activity and mitochondrial volume

Human Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1) interaction partners

  1. Mitochondrial creatine kinase (显示 CKMT2 蛋白) CKMT1 (显示 CKMT1B 蛋白) is necessary for survival of EVI1 (显示 MECOM 蛋白)-expressing cells in subjects with EVI1 (显示 MECOM 蛋白)-positive AML (显示 RUNX1 蛋白).

  2. CKMT1 (显示 CKMT1B 蛋白) is a key regulator of the permeability transition pore through a complex that is distinct from the classical permeability transition pore.

  3. the knock-down of the mitochondrial creatine kinase (显示 CKMT2 蛋白)-1 (CKMT1 (显示 CKMT1B 蛋白)) by RNA interference causes the dissipation of the mitochondrial membrane potential

  4. ASB9 (显示 ASB9 蛋白) interacts with the creatine kinase system and negatively regulates cell growth.

  5. MtCK, but not NDPK-D (显示 NME4 蛋白), shows some specificity in the nature of the lipids transferred and it is not active with phosphatidylcholine (显示 SGMS2 蛋白) alone

  6. uMtCK (显示 CKMT1B 蛋白) in prostate neoplasm cells (LNCaP) contributes to overproduction of reactive oxygen species, activation of Akt (显示 AKT1 蛋白) signaling pathway and more aggressive phenotypes including androgen independence development.

蛋白简介Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1)

蛋白简介

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase\; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

Gene names and symbols associated with CKMT1

  • creatine kinase, mitochondrial 1 (ckmt1)
  • creatine kinase, mitochondrial 1, ubiquitous (Ckmt1)
  • creatine kinase, mitochondrial 1A (CKMT1A)
  • creatine kinase, mitochondrial 1B (Ckmt1b)
  • creatine kinase, mitochondrial 1B (CKMT1B)
  • Ckmt1 蛋白
  • fb37h03 蛋白
  • fb69a12 蛋白
  • mi-CK 蛋白
  • Mt-CK 蛋白
  • ScCKmit 蛋白
  • UbCKmit 蛋白
  • wu:fb37h03 蛋白
  • wu:fb69a12 蛋白

Protein level used designations for CKMT1

creatine kinase U-type, mitochondrial , U-MtCK , acidic-type mitochondrial creatine kinase , mia-CK , ubiquitous mitochondrial creatine kinase , creatine kinase, mitochondrial 1 (ubiquitous) , creatine kinase, mitochondrial 1, ubiquitous

GENE ID SPECIES
321892 Danio rerio
12716 Mus musculus
548596 Homo sapiens
29593 Rattus norvegicus
281692 Bos taurus
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