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COL5A2 encodes an alpha chain for one of the low abundance fibrillar collagens. 再加上，我们可以发COL5A2 抗体 (31) 和 COL5A2 蛋白 (5)和数多这个蛋白质的别的产品。
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COL5A2(+/-) humans, although unlikely to present with frank classic Ehlers-Danlos syndrome, are likely to have fragile connective tissues with increased susceptibility to trauma and certain chronic pathologic conditions.
data confirm that COL5A1 (显示 COL5A1 ELISA试剂盒) and COL5A2 are the major, if not the only, genes involved in classic Ehlers-danlos syndrome
Col5a2 shows predictive potential in myocardial infarction , and in principle may represent a novel candidate marker for the identification and treatment of ischemic cardiovascular disease
study shows that over 90% of patients, which strictly satisfy all major Villefranche criteria for classic Ehlers-Danlos Syndrome (EDS)harbor a type V collagen (显示 COL5A1 ELISA试剂盒) defect which indicates that this is the major--if not only--cause of classic EDS
This study suggests a fetal association of COL5A2 and a combined fetal-maternal association of COL5A1 (显示 COL5A1 ELISA试剂盒) with spontaneous preterm delivery.
Before but not after developing bronchiolitis obliterans, lung transplantation patients had antibodies to Col (显示 HDAC1 ELISA试剂盒)-V, alpha2(V). Pep5 (显示 VPS11 ELISA试剂盒)-8 to alpha1,2(V) and pep9-14 to alpha2(V)were immunodominant.
Physical and laboratory examinations revealed that true haploinsufficiency of COL3A1 (显示 COL3A1 ELISA试剂盒), COL5A2, and MSTN (显示 MSTN ELISA试剂盒), but not that of SLC40A1 (显示 SLC40A1 ELISA试剂盒), leads to a clinical phenotype.
Mutations in the COL5A2 gene have been identified by DNA sequence analysis in 10 patients with spontaneous vertebral artery dissections.
analysis of processing of the Pro-alpha1(V)Pro-alpha2(V)Pro-alpha3(V (显示 COL5A3 ELISA试剂盒)) procollagen heterotrimer
In the eye, COL5A1 (显示 COL5A1 ELISA试剂盒) and COL5A2 mutations manifest as abnormally thin and steep corneas with floppy eyelids.
Col5a2 haploinsufficiency markedly increased the incidence and severity of abdominal aortic aneurysms.
Mice with null alleles for the Col5a2. Col5a2(-/-) homozygosity is embryonic lethal at approximately 12 days post conception.
This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II.
alpha 2 type V collagen
, collagen alpha-2(V) chain
, collagen, type V, alpha 2
, collagen, type V, alpha-2 chain
, collagen alpha-2(V) chain-like
, AB collagen
, collagen, fetal membrane, A polypeptide
, type V preprocollagen alpha 2 chain
, procollagen, type V, alpha 2
, collagen type V alpha 2