anti-Coagulation Factor X (F10) 抗体

F10 encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. 再加上,我们可以发Coagulation Factor X 试剂盒 (59)Coagulation Factor X 蛋白 (28)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
F10 2159 P00742
F10 14058 O88947
F10 29243 Q63207
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Showing 10 out of 241 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-F10 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-F10 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control:.21_B cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 ELISA, WB Western blot analysis of extracts from rat liver cells, using FA10 (activated heavy chain,Cleaved-Ile235) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 ELISA, WB Western blot analysis of extracts from A549 cells, treated with etoposide 24uM 24h, using FA10 (light chain,Cleaved-Ala41) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 EIA, WB 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 FACS, IHC (p), WB Western blot analysis of F10 antibody (C-term) (ABIN390688) in 293 cell line lysates (35 µg/lane). F10 (arrow) was detected using the purified polyclonal antibody. F10 Antibody (C-term) (ABIN390688) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10至11个工作日
$324.50
详细
小鼠 非结合性 EIA, WB   0.2 mg Log in to see 6至8个工作日
$555.50
详细
非结合性 ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded A549 xenograft, using Factor X, antibody at 1:500 dilution. ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using Factor X, antibody at 1:200 dilution. 100 μL Log in to see 1至2个工作日
$358.60
详细
非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 IHC, WB Western blot analysis of extracts of Raji and mouse liver cell lines, using F10 antibody. 100 μL Log in to see 16 Days
$323.13
详细
非结合性 WB   200 μL Log in to see 13至14个工作日
$487.50
详细

通过反应活性、应用领域、克隆类型和共轭标记 F10 抗体

特性 应用范围 宿主 克隆类型 标记
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更多抗Coagulation Factor X的相互作用对抗体

Human Coagulation Factor X (F10) interaction partners

  1. Data suggest that, for all coagulation proteins tested (prothrombin, factor X, activated factor VII, activated protein C), tighter binding to lipid bilayers (lower Kd) is observed as the proportion of anionic phospholipid increases. These studies were conducted in high-throughput screening using phospholipid bilayers in nanodiscs with multiplexed silicon photonic sensor (micro-ring resonator) array technology.

  2. A coagulation initiating pathway is revealed in which the TF-FVIIa-nascent FXa complex activates FVIII (显示 F8 抗体) apart from thrombin (显示 F2 抗体) feedback.

  3. Data suggest oxidized lipid vesicles with phosphatidylserine/polyunsaturated fatty acids promote inactivation of ZPI (显示 SERPINA10 抗体)-PZ complex or free ZPI (显示 SERPINA10 抗体); binding of PZ-complexed or free ZPI (显示 SERPINA10 抗体) to oxidized vesicles mediates inactivation of ZPI (显示 SERPINA10 抗体) (an inhibitor of FXa); blocking heparin- (anticoagulant-)binding site on ZPI (显示 SERPINA10 抗体) interferes with binding to lipid or PZ. (ZPI (显示 SERPINA10 抗体) = protein Z-dependent protease inhibitor (显示 SERPINA10 抗体); PZ = protein Z (显示 PROZ 抗体); FXa = factor Xa)

  4. Factor Va reduced by 100-fold the apparent Kd of myosin for factor Xa (Kd approximately 0.48 nM), primarily by reducing koff, indicating formation of a stable ternary complex of myosin:Xa:Va.

  5. PTX2 (显示 APCS 抗体) was identified PTX2 (显示 APCS 抗体) as a novel partner for FX, and both proteins cooperated to prevent their SR-AI (显示 MSR1 抗体)-mediated uptake by macrophages.

  6. annexin A2 (显示 ANXA2 抗体) contributes to lung injury and fibrotic disease by mediating the fibrogenic actions of FXa.

  7. Individuals suffering from relapsing-remitting and secondary progressive multiple sclerosis had significantly higher prothrombin (显示 F2 抗体) and factor X levels than healthy donors, whereas levels were unchanged in primary progressive MS and neuromyelitis optica patients.

  8. Low concentrations of TF and exogenous FXIa, each too low to elicit a burst in thrombin (显示 F2 抗体) production alone, act synergistically when in combination to cause substantial thrombin (显示 F2 抗体) production.

  9. analysis of how physiological concentrations of Tissue factor pathway inhibitor (显示 TFPI 抗体) inhibit FXa

  10. According to our study, compounds 1a, 1g and 1s displayed evident FXa inhibitory activity and excellent selectivity over thrombin (显示 F2 抗体) in in vitro inhibition activities studies.

Mouse (Murine) Coagulation Factor X (F10) interaction partners

  1. PTX2 (显示 PITX2 抗体) was identified PTX2 (显示 PITX2 抗体) as a novel partner for FX, and both proteins cooperated to prevent their SR-AI (显示 MSR1 抗体)-mediated uptake by macrophages.

  2. annexin A2 (显示 ANXA2 抗体) contributes to lung injury and fibrotic disease by mediating the fibrogenic actions of FXa.

  3. Enhanced FXa and PAR2 (显示 F2RL1 抗体) exacerbate DN and that both are promising targets for preventing diabetic nephropathy.

  4. Macrophages regulate FX plasma levels in an SR-AI (显示 MSR1 抗体)-dependent manner.

  5. Factor Xa has a role in inhibiting HMGB1 (显示 HMGB1 抗体)-induced septic responses in human umbilical vein endothelial cells and in mice

  6. Selective inhibition of FXa improves the left ventricular function during CVB3-induced myocarditis and seems to be associated with an improved myocardial remodeling.

  7. Activated factor X signaling via protease-activated receptor 2 (显示 F2RL1 抗体) suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells.

  8. There was no detectable increase in plasma levels of mouse FX after active-site inhibited human APC (显示 APC 抗体) administration to mice overexpressing human EPCR (显示 PROCR 抗体). FX does not effectively interact with EPCR (显示 PROCR 抗体) in vivo, at least in regards to the mouse system.

  9. investigation of role of F10a in progression of diabetic nephropathy: data from studies using inhibitor of F10a suggest that F10a does play a role in development of proteinemia, glomerular hypertrophy, and protein deposition in kidney of db/db (显示 LEPR 抗体) mice

  10. Data suggest that tissue factor (显示 F3 抗体) and factor V induction by LPS (显示 TLR4 抗体) may in part accelerate mesangioproliferative glomerulonephritis through activation of factor X and downstream proinflammatory and procoagulant mechanisms.

Cow (Bovine) Coagulation Factor X (F10) interaction partners

  1. Data suggest factor Xa (FXa) and factor Va (FVa) compete to bind FXa on both PS model membranes and microparticles from activated platelets; this competition between dimerization/prothrombinase (显示 FGL2 抗体) complex formation appears to regulate blood coagulation.

  2. thrombin (显示 F2 抗体) and factor Xa diffusion along the heparin molecule explains the effects of extended heparin chain lengths

  3. Factor Xa (fXa), a key serine protease (显示 F2 抗体) of the coagulation system, was used as a model enzyme to test the canonical conformation hypothesis.

Zebrafish Coagulation Factor X (F10) interaction partners

  1. These findings as well as the prolonged survival of f10(-/-) mutants will enable us to expand our understanding of the molecular mechanisms of hemostasis, including a platform for screening variants of uncertain significance in patients with F10 deficiency and other coagulation disorders

Coagulation Factor X (F10) 抗原简介

蛋白简介

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds\; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.

Gene names and symbols associated with anti-Coagulation Factor X (F10) 抗体

  • coagulation factor X (F10) 抗体
  • coagulation factor X (f10) 抗体
  • coagulation factor X (CpipJ_CPIJ012712) 抗体
  • coagulation factor X (CpipJ_CPIJ014863) 抗体
  • coagulation factor X (CpipJ_CPIJ016937) 抗体
  • coagulation factor X (CpipJ_CPIJ017791) 抗体
  • Coagulation factor X (fa10) 抗体
  • coagulation factor 10 L homeolog (f10.L) 抗体
  • Cf10 抗体
  • f10 抗体
  • fi12c10 抗体
  • fX 抗体
  • FXA 抗体
  • wu:fi12c10 抗体

Protein level used designations for anti-Coagulation Factor X (F10) 抗体

Stuart-Prower factor , factor Xa , prothrombinase , stuart factor , coagulation factor 10 , VAP , factor XA light chain , virus activating protease , virus-activating protease , coagulation factor X , vitamin K dependent serine protease , coagulation factor X preproprotein , blood coagulation factor X , Coagulation factor X , coagulation factor 10 L homeolog

GENE ID SPECIES
2159 Homo sapiens
14058 Mus musculus
29243 Rattus norvegicus
280787 Bos taurus
282670 Danio rerio
395876 Gallus gallus
445942 Takifugu rubripes
452679 Pan troglodytes
476993 Canis lupus familiaris
714132 Macaca mulatta
790961 Ornithorhynchus anatinus
6045845 Culex quinquefasciatus
6048453 Culex quinquefasciatus
6050511 Culex quinquefasciatus
6052088 Culex quinquefasciatus
100008647 Oryctolagus cuniculus
100022394 Monodelphis domestica
100137443 Papio anubis
100380501 Salmo salar
100408094 Callithrix jacchus
100453258 Pongo abelii
100471482 Ailuropoda melanoleuca
100607918 Nomascus leucogenys
100726878 Cavia porcellus
101118624 Ovis aries
398778 Xenopus laevis
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