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Coagulation Factor VIII (F8) ELISA试剂盒

F8 encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. 再加上,我们可以发Factor VIII 抗体 (351)Factor VIII 蛋白 (33)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
F8 14069 Q06194
F8 2157 P00451
F8 302470  

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Showing 10 out of 51 products:

产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
31.25 ng/mL 125-8000 ng/mL Typical standard curve 96 Tests Log in to see 13至17个工作日
¥4,654.26
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小鼠 0.078 ng/mL 0.312-20 ng/mL Typical standard curve 96 Tests Log in to see 11至15个工作日
¥3,994.38
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30 pg/mL 78-5.000 pg/mL 96 Tests Log in to see 11至15个工作日
¥3,310.81
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小鸡 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 10至13个工作日
¥4,982.30
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0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 10至13个工作日
¥4,982.30
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Pig 0.469 ng/mL 0.781-50 ng/mL   96 Tests Log in to see 10至13个工作日
¥4,982.30
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18.75 pg/mL 31.25-2000 pg/mL   96 Tests Log in to see 10至13个工作日
¥4,982.30
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大鼠 4.688 pg/mL 7.813-500 pg/mL   96 Tests Log in to see 10至13个工作日
¥5,145.66
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  96 Tests Log in to see 24至29个工作日
¥3,747.51
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绵羊
  96 Tests Log in to see 13至17个工作日
¥3,411.38
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适于 Factor VIII 相互作用对的更多 ELISA 试剂盒

Zebrafish Coagulation Factor VIII (F8) interaction partners

  1. gene is flanked by factor VII (显示 TH ELISA试剂盒) and factor X genes; gene encodes a protein homologous to factor VII (显示 TH ELISA试剂盒), but lacks critical residues for factor VII (显示 TH ELISA试剂盒) activity; functions as an inhibitor of blood coagulation in biochemical assays using zebrafish or human plasmas

Mouse (Murine) Coagulation Factor VIII (F8) interaction partners

  1. data demonstrate that infusion of platelets containing FVIII triggers neither primary nor memory anti-FVIII immune response in FVIII(null) mice

  2. Both platelet-VWF (显示 VWF ELISA试剂盒) and plasma-VWF (显示 VWF ELISA试剂盒) are required for optimal platelet-derived FVIII gene therapy for hemophilia A in the presence of inhibitors.

  3. These data support the investigation of FVIII orthologs as treatment modalities in both the congenital and acquired FVIII inhibitor settings.

  4. Activatable bioengineered FIX molecules with FVIII-independent activity might be a promising tool for improving hemophilia A treatment, especially for patients with inhibitors.

  5. This study demonstrated that FVIIIa interacts with Low-density lipoprotein receptor-related protein 1 (显示 LRP1 ELISA试剂盒) cluster III.

  6. a fragment containing only approximately 20% of the VWF (显示 VWF ELISA试剂盒) sequence is sufficient to support FVIII stability in vivo

  7. Endothelial cells from multiple, but not all, tissues contribute to the plasma FVIII pool in the mouse.

  8. Endothelial cells are the predominant, and possibly exclusive, source of plasma FVIII.

  9. Micro-computed tomography analysis of distal tibia metaphyses also revealed for the first time a major impact of the FVIII/thrombin (显示 F2 ELISA试剂盒)/PAR1 (显示 F2R ELISA试剂盒) axis on the dynamic bone structure, showing reduced bone.

  10. Findings indicate that improving protein trans-splicing by inter-chain disulfide bonding is a promising approach for increasing the efficacy of dual-vector based FVIII gene transfer.

Human Coagulation Factor VIII (F8) interaction partners

  1. The FVIII B domain variants, p.D963N, p.S806T, p.G873D, p.H998Q and p.Q1225R may be considered as polymorphism or non-pathologic mutations in patients with Haemophilia A.

  2. In this meta-analysis, we have assessed the association between the FXIII-A Val34Leu polymorphism and intracerebral hemorrhage risk. The results of a combined analysis showed no significant association between the FXIII-A Val34Leu polymorphism and ICH (显示 COL4a2 ELISA试剂盒) risk in the overall population. The results of this meta-analysis suggest that the FXIII-A Val34Leu polymorphism is not associated with ICH (显示 COL4a2 ELISA试剂盒) risk in a Caucasian population.

  3. von Willebrand factor (显示 VWF ELISA试剂盒) binds to the surface of dendritic cells and modulates peptide presentation of factor VIII.

  4. Desmopressin acetate increases F8 plasma concentration in patients with combined deficiency of factors V and VIII (显示 COX8A ELISA试剂盒).

  5. 37 (70%) of the 53 had discordant antigen-activity ratio, majority of those mutations produced FVIII with low FVIII-specific activity. However, 4 (7.5%) of the 53 mutations produced higher specific activity of FVIII. It is possible that these mutations either produce a secretory defect or an increased metabolic turnover to account for the low levels of FVIII with these mutations.

  6. Platelet-targeted FVIII gene therapy has higher therapeutic efficacy compared to factor VIII replacement therapy may be due to accelerated thrombin (显示 F2 ELISA试剂盒) generation.

  7. Letter: report deep intronic variants of factor VII (显示 TH ELISA试剂盒) gene in hemophilia A.

  8. Coagulation test results showed that the presence of double Glu113Asp, Arg593Cys mutations has a slightly synergistic effect on FVIII activity.

  9. Report a dose-response relationship between high FVIII levels and risk of death in venous thrombosis patients and in individuals from the general population.

  10. Case Report: P1809L mutation in A3 induced the conformational change in the FVIII molecule that hampered antigenic determinant(s) located in the C2 domain and might result in the inhibitor development.

Pig (Porcine) Coagulation Factor VIII (F8) interaction partners

  1. thrombin (显示 F2 ELISA试剂盒) stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (显示 UGDH ELISA试剂盒) and by receptor-mediated up-regulation of factor XIII (显示 UGDH ELISA试剂盒) synthesis

  2. cupredoxin-like A1 subdomains in fVIII contain inter-species differences that are a result of selective pressure on the dissociation rate constant

Cow (Bovine) Coagulation Factor VIII (F8) interaction partners

  1. Factor VIIIc (显示 COX7A2 ELISA试剂盒) is responsible for tissue invasion during tumor progression.

Factor VIII (F8) 抗原简介

Antigen Summary

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Gene names and symbols associated with F8

  • coagulation factor VIIi (f7i) 抗体
  • coagulation factor VIII (F8) 抗体
  • coagulation factor VIII, procoagulant component (F8) 抗体
  • AHF 抗体
  • Cf-8 抗体
  • Cf8 抗体
  • DXS1253E 抗体
  • F8B 抗体
  • F8C 抗体
  • fb61d02 抗体
  • FVIII 抗体
  • HEMA 抗体
  • wu:fb61d02 抗体

Protein level used designations for F8

Factor VIII , procoagulant component , antihemophilic factor , coagulation factor VIII , coagulation factor VIIIc , factor VIII F8B , coagulation factor VIII, procoagulant component (hemophilia A) , factor VIII , coagulation co-factor

GENE ID SPECIES
282671 Danio rerio
14069 Mus musculus
2157 Homo sapiens
397339 Sus scrofa
403875 Canis lupus familiaris
100271720 Bos taurus
100303761 Oryctolagus cuniculus
302470 Rattus norvegicus
100359363 Ovis aries
422199 Gallus gallus
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