Chromobox Homolog 8 (CBX8) ELISA试剂盒

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. 再加上,我们可以发CBX8 抗体 (154)CBX8 蛋白 (3)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
小鼠 CBX8 CBX8 30951 Q9QXV1
 CBX8 CBX8 57332 Q9HC52
大鼠 CBX8 CBX8 303731  
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适于 CBX8 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) Chromobox Homolog 8 (CBX8) interaction partners

  1. Cbx8 associates with non-PRC1 (显示 PRC1 ELISA试剂盒) complexes containing the H3K4 methyltransferase complex component WDR5 (显示 WDR5 ELISA试剂盒), which together regulate Notch (显示 NOTCH1 ELISA试剂盒) gene expression.

  2. CBX8 plates roles in epigenetic regulation in DNA damage response.

  3. Cbx8 is upregulated and recruited to activated genes during embryonic stem cell differentiation.

  4. CBX8 plays an essential role in MLL (显示 MLL ELISA试剂盒)-AF9 (显示 MLLT3 ELISA试剂盒) transcriptional regulation and leukemogenesis.

  5. Pcl2-PRC2 facilitates both PRC2 recruitment to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells.

  6. Huntingtin (显示 HTT ELISA试剂盒) is a novel stimulator of polycomb (显示 CBX2 ELISA试剂盒) repressive complex 2.

Human Chromobox Homolog 8 (CBX8) interaction partners

  1. The data suggest that high expression of CBX8 plays a critical oncogenic role in aggressiveness of urothelial carcinoma cells of the bladder through promoting cancer cell proliferation by repressing the p53 (显示 TP53 ELISA试剂盒) pathway, and CBX8 could be used as a novel predictor for muscle invasive bladder cancer patients.

  2. CBX8 binds to H3K27me3 at bivalent promoters during germinal center formation, and recruits a novel PRC1 (显示 PRC1 ELISA试剂盒)-BCOR (显示 BCOR ELISA试剂盒) complex at BCL6 (显示 BCL6 ELISA试剂盒) binding sites to specifically silence genes in the germinal center and promote lymphomagenesis

  3. CBX8 plates roles in epigenetic regulation in DNA damage response.

  4. IGF1 (显示 IGF1 ELISA试剂盒) can promote the colon cancer cell line, HCT116 cell, proliferation via promoting Cbx8 expression

  5. The difference in the SUZ12 and CBX8 genes expression were significantly divergent between tumors and their marginal tissues.

  6. These data suggest that CBX8 modulates SIPS through the RB-E2F1 pathway in CML cells and provide important insight into its application in CML treatment.

  7. Low CBX8 expression was associated with distant metastasis in colorectal cancer.

  8. CBX8 might emerge as an oncogene (显示 RAB1A ELISA试剂盒) for promoting the proliferation of tumor cells and raising the resistance of neoplasms to chemotherapy.

  9. The presence of CBX8-GFP in the same focus had a minor impact on BMI1 and RING1 recovery kinetics.

  10. Interaction with CBX8 precludes AF9 (显示 MLLT3 ELISA试剂盒)-DOT1L (显示 DOT1L ELISA试剂盒) binding.

CBX8 抗原简介

Antigen Summary

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Gene names and symbols associated with CBX8

  • chromobox 8 (cbx8) 抗体
  • chromobox 8 (CBX8) 抗体
  • chromobox 8 (Cbx8) 抗体
  • chromobox 8 S homeolog (cbx8.S) 抗体
  • chromobox homolog 8a (Pc class homolog, Drosophila) (cbx8a) 抗体
  • cbx8 抗体
  • MGC147589 抗体
  • PC3 抗体
  • RC1 抗体

Protein level used designations for CBX8

chromobox homolog 8 , chromobox protein homolog 8 , mPc3 , polycomb 3 homolog , Pc class 3 homolog , chromobox homolog 8 (Pc class homolog, Drosophila) , polycomb 3 , rectachrome 1 , chromobox-like protein 8 , chromobox homolog 8 (Pc class homolog) , chromobox homolog 8a

GENE ID SPECIES
779897 Xenopus (Silurana) tropicalis
100604409 Nomascus leucogenys
30951 Mus musculus
57332 Homo sapiens
608591 Canis lupus familiaris
506458 Bos taurus
303731 Rattus norvegicus
496172 Xenopus laevis
100514536 Sus scrofa
422084 Gallus gallus
100150672 Danio rerio
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