Chemokine (C-X-C Motif) Ligand 10 蛋白 (CXCL10)

CXCL10 encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. 再加上,我们可以发CXCL10 抗体 (338)CXCL10 试剂盒 (122)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
CXCL10 3627 P02778
CXCL10 15945 P17515
CXCL10 245920 P48973

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Showing 10 out of 92 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
大肠杆菌(E. Coli) 小鼠 非结合性 25 μg Log in to see 28至34个工作日
¥1,687.00
详细
大肠杆菌(E. Coli) His tag Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98), (full length) protein (His tag) 50 μg Log in to see 7至10个工作日
¥1,126.55
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大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 48至57个工作日
¥108,861.33
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 68至72个工作日
¥136,777.64
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大肠杆菌(E. Coli) 非结合性 4 pack Log in to see 28至34个工作日
¥710.27
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大肠杆菌(E. Coli) 非结合性   10 μg Log in to see 28至34个工作日
¥843.46
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大肠杆菌(E. Coli) 非结合性 100 μg Log in to see 14至15个工作日
¥4,502.45
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大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 48至57个工作日
¥108,861.33
详细
大肠杆菌(E. Coli) 小鼠 非结合性 100 μg Log in to see 26至32个工作日
¥3,984.54
详细
大肠杆菌(E. Coli) 非结合性 100 μg Log in to see 26至32个工作日
¥3,984.54
详细

CXCL10 蛋白 by Origin and Source

Origin 在表达 标记
Human , , , , ,
, , , ,
Mouse (Murine) ,
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Rat (Rattus) ,
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引用最多的CXCL10 蛋白

  1. Mouse (Murine) CXCL10 Protein expressed in Escherichia coli (E. coli) - ABIN2666633 : Luster, Unkeless, Ravetch: Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins. in Nature 1985 (PubMed)
    Show all 6 references for 2666633

  2. Human CXCL10 Protein expressed in Escherichia coli (E. coli) - ABIN2667390 : Campanella, Colvin, Luster: CXCL10 can inhibit endothelial cell proliferation independently of CXCR3. in PLoS ONE 2010 (PubMed)
    Show all 6 references for 2667390

  3. Human CXCL10 Protein expressed in Escherichia coli (E. coli) - ABIN2666630 : Crawford, Zhu, Green, Burdick, Sanz, Alem, OBrien, Mehrad, Strieter, Hughes: Antimicrobial effects of interferon-inducible CXC chemokines against Bacillus anthracis spores and bacilli. in Infection and immunity 2009 (PubMed)
    Show all 5 references for 2666630

  4. Human CXCL10 Protein expressed in Escherichia coli (E. coli) - ABIN1046708 : Proost, De Wolf-Peeters, Conings, Opdenakker, Billiau, Van Damme: Identification of a novel granulocyte chemotactic protein (GCP-2) from human tumor cells. In vitro and in vivo comparison with natural forms of GRO, IP-10, and IL-8. in Journal of immunology (Baltimore, Md. : 1950) 1993 (PubMed)
    Show all 4 references for 1046708

  5. Human CXCL10 Protein expressed in Escherichia coli (E. coli) - ABIN2003369 : ODonovan, Galvin, Morgan: Physical mapping of the CXC chemokine locus on human chromosome 4. in Cytogenetics and cell genetics 1999 (PubMed)

更多Chemokine (C-X-C Motif) Ligand 10 (CXCL10)互动伙伴

Pig (Porcine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. a SNP in CXCL10 was significantly associated with percentage of lymphocyte in blood of 20-day-old pigs and with hematocrit and mean red cell volume in blood of 80-day-old pigs

  2. CXCL10 protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 (显示 CCL2 蛋白) mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.

  3. Authors identified chemokine (C-X-C motif) ligand 10 (CXCL10), also named interferon-gamma inducible protein-10 (IP-10), as a novel target gene of miR (显示 MYLIP 蛋白)-21.

  4. These in vitro and in vivo observations suggest that interferon-gamma inducible protein 10 (IP-10) may be a reliable biomarker for immune activity induced by CpG oligodeoxynucleotides in pigs.

  5. The swine CXCL10 gene contains four exons and three introns.

Human Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. Data suggest that, unlike non-metastatic intestinal epithelial cells (IECs), metastatic IECs express TLR3 (显示 TLR3 蛋白) and that TLR3 (显示 TLR3 蛋白) agonists induce inflammatory cytokine (CXCL10) production and promote invasiveness of IECs. (TLR3 (显示 TLR3 蛋白) = toll-like receptor 3 (显示 TLR3 蛋白); CXCL10 = chemokine (显示 CCL1 蛋白) [C-X-C motif] ligand 10 protein)

  2. Studied perinatally HIV-infected children on cART and in good clinical status with respect to HIV disease; found that high plasma levels of Interferon-gamma-inducible protein 10 (IP10) associate with increased numbers of abnormal memory B cells (MBCs) phenotypes. IP10 appears to be a sensitive marker to predict the presence of exhausted MBC.

  3. These data suggest that elevated IP-10 levels may impair NK cell function during HIV infection and that IP-10/CXCR3 (显示 CXCR3 蛋白) blocking may be a novel therapeutic strategy in the control and functional cure of HIV.

  4. Results provide evidence for an association between an increase level of CCL21 (显示 CCL21 蛋白) and IP-10 in the blood and pulmonary involvement in systemic lupus erythematosus patients.

  5. findings show that S. aureus downregulates superantigen-induced IP-10 production and prevents Th1 (显示 TH1L 蛋白) cell recruitment; S. aureus triggered activation of MAPKs p38 (显示 CRK 蛋白) and ERK (显示 EPHB2 蛋白), as well as inhibition of STAT1 (显示 STAT1 蛋白) signaling in monocytes, altogether contributing to the downregulation of IP-10

  6. Mothers of children affected by autoimmune congenital heart block did not have significantly elevated levels of IP-10 expression.

  7. results indicate that rhinovirus (RV) stimulates CXCL-10 expression via the IL-33 (显示 IL33 蛋白)/ST2 (显示 SULT2A1 蛋白) signaling axis, and that TLR2 signaling limits RV-induced CXCL-10 via IRAK-1 (显示 IRAK1 蛋白) depletion at least in airway epithelial cells

  8. This would suggest that the change in IP-10 is genotypically driven, while the change in IL-6 (显示 IL6 蛋白) may be reflective of systemic lupus erythematosus (SLE) transition status. These data suggest that IFIH1 (显示 IFIH1 蛋白) may contribute to SLE pathogenesis via altered inflammatory mechanisms.

  9. HCV infection leads to upregulated expression of CXCL10 in brain microvascular endothelial cells, which is probably via the phosphorylation of NF-kappaB (显示 NFKB1 蛋白).

  10. The results indicate significantly increased levels of CXCL10 protein in the urine at the time of allograft rejection. This association of urinary CXCL10 protein levels with rejection could provide an additional tool for the non-invasive monitoring of allograft rejection.

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. this study shows that neutrophils and NK cells act as important disease-promoting immune cells in experimental osteoarthritis and their functional interaction is promoted by the CXCL10/CXCR3 (显示 CXCR3 蛋白) axis

  2. CXCL10 chemokine (显示 CCL1 蛋白) levels correlate negatively with gremlin-1 (显示 GREM1 蛋白) levels in mouse and human lung.

  3. Increased CXCL10 expression led to decreased tumour burden and malignant ascites accumulation in the ID8 syngeneic murine model of HGSC.

  4. These findings demonstrate that the CXCL10/CXCR3 (显示 CXCR3 蛋白) chemokine (显示 CCL1 蛋白) pathway is critical in shaping CD8 (显示 CD8A 蛋白)(+) T cell immunity, locally within latently infected tissues, which protects against recurrent herpesvirus infection and disease.

  5. CXCL10 plays in the pathogenesis of recurrent Herpetic stromal keratitis, and that CXCL9 (显示 CXCL9 蛋白) displays its importance when CXCL10 is absent.

  6. PERK (显示 EIF2AK3 蛋白) and IRE1alpha (显示 ERN1 蛋白)/XBP1 (显示 XBP1 蛋白) in the unfolded protein response differentially regulate the expression of CXCL10 and CCL2 (显示 CCL2 蛋白) likely through modulation of ER stress-induced NF-kappaB (显示 NFKB1 蛋白) RelA (显示 NFkBP65 蛋白) and STAT3 (显示 STAT3 蛋白) activation.

  7. CXCL10 might influence the cellular composition locally in the islet graft, thereby playing a role in the autoimmune destruction. CXCL10 might therefore constitute a potential therapeutic target to prolong islet graft survival

  8. Data provide first evidence for a link between oncogenic JAK2V617F signaling and cell intrinsic induction of CXCL10 induced by activated NFkB signaling.

  9. Genome-wide expression of isolated Kupffer cells following pressure-controlled hemorrhage revealed a significant increase of gene expression of Cxcl10, Il4ra, Csf2rb2, Lcn2, and Gbp5, which might represent new biomarkers for early diagnosis of post-traumatic complications.

  10. Donor interleukin-22 (显示 IL22 蛋白) and host type I interferon (显示 IFNA 蛋白) signaling pathway participate in intestinal graft-versus-host disease via STAT1 (显示 STAT1 蛋白) activation and CXCL10.

Cow (Bovine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. These results demonstrated that bovine colonic cells seem capable to respond to E. bovis merozoite I infection by the upregulation of CXCL10 and GM-CSF (显示 CSF2 蛋白) gene transcription.

  2. IL-17A (显示 IL17A 蛋白) was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.

蛋白简介CXCL10

蛋白简介

This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression.

Gene names and symbols associated with CXCL10

  • chemokine (C-X-C motif) ligand 10 (CXCL10)
  • C-X-C motif chemokine 10 (cxl10)
  • chemokine (C-X-C motif) ligand 10 (Cxcl10)
  • C7 蛋白
  • CRG-2 蛋白
  • CXCL10 蛋白
  • gIP-10 蛋白
  • Ifi10 蛋白
  • INP10 蛋白
  • IP-10 蛋白
  • IP10 蛋白
  • mob-1 蛋白
  • Scyb10 蛋白

Protein level used designations for CXCL10

chemokine (C-X-C motif) ligand 10 , C-X-C motif chemokine 10 , chemokine CXC-like protein , chemokine C-X-C motif ligand 10 , C-X-C motif chemokine 10-like protein , 10 kDa interferon gamma-induced protein , gamma IP10 , gamma-IP10 , interferon-inducible cytokine IP-10 , protein 10 from interferon (gamma)-induced cell line , small inducible cytokine subfamily B (Cys-X-Cys), member 10 , small-inducible cytokine B10 , interferon activated gene 10 , interferon-gamma induced protein CRG-2 , interferon-gamma-induced protein CRG-2 , small inducible cytokine B subfamily (Cys-X-Cys), member 10 , interferon-inducible protein 10 , protein Mob-1 , small inducible cytokine B subfamily (Cys-X-Cys) member 10 , gamma interferon inducible protein 10 , CXC chemokine ligand 10 , interferon-gamma-inducible protein 10 , interferon-gamma-inducible protein-10 , 10 kDa interferon-gamma-induced protein , 10 kDa interferon-gamma-inducible protein CXCL10 , IP-10 , small inducible cytokine B10

GENE ID SPECIES
461242 Pan troglodytes
494019 Sus scrofa
100050993 Equus caballus
100195999 Salmo salar
3627 Homo sapiens
15945 Mus musculus
245920 Rattus norvegicus
615107 Bos taurus
478432 Canis lupus familiaris
442997 Ovis aries
574243 Macaca mulatta
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