anti-Chemokine (C-C Motif) Receptor 4 (CCR4) 抗体

The protein encoded by CCR4 belongs to the G-protein-coupled receptor family . 再加上,我们可以发CCR4 试剂盒 (25)CCR4 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CCR4 104625 Q8K3P5
CCR4 287249 Q6AXU9
CCR4 1233 P51679

antibodies-online.cn销售最多的anti-CCR4 抗体

Showing 10 out of 211 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-CCR4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 IF (p), IHC (p) Formalin-fixed and paraffin embedded rat exfoliated cells tissue labeled with Anti-CCR4 Polyclonal Antibody, Unconjugated (ABIN738666) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat cells labeled with Anti-CCR4/CD194 Polyclonal Antibody, Unconjugated (ABIN738666) followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 5至7个工作日
¥2,709.56
详细
小鼠 Fluorescein FACS Detection of CCR4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human/Rat CCR4 Fluorescein-conjugated Monoclonal Antibody. Detection of CCR4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human/Rat CCR4 Fluorescein-conjugated Monoclonal Antibody. 25 Tests Log in to see 26至31个工作日
¥1,072.01
详细
小鼠 PE FACS Detection of CCR4 in Rat Peripheral Blood Cells by Flow Cytometry. Rat peripheral blood cells were stained with Mouse Anti-Human/Rat CCR4 PE-conjugated Monoclonal Antibody. Detection of CCR4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD3 epsilon APC-conjugated Monoclonal Antibody. 25 Tests Log in to see 26至31个工作日
¥1,072.01
详细
小鼠 Allophycocyanin FACS Detection of CCR4 in Rat Splenocytes by Flow Cytometry. Rat splenocytes were stained with Mouse Anti-Human/Rat CCR4 APC-conjugated Monoclonal Antibody. Detection of CCR4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD3 epsilon PE-conjugated Monoclonal Antibody. 25 Tests Log in to see 26至31个工作日
¥1,149.20
详细
小鼠 非结合性 FACS Detection of CCR4 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD4 APC-conjugated Monoclonal Antibody. Detection of CCR4 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD4 APC-conjugated Monoclonal Antibody. 100 μg Log in to see 26至31个工作日
¥2,529.95
详细
山羊 非结合性 ICC, FACS, IHC (fro), IF, IHC (p), IHC, ELISA, WB Immunohistochemistry on paraffin section of human spleen 0.1 mg Log in to see 25至31个工作日
¥3,119.56
详细
Cow 非结合性 EIA, IHC (fro), IP, WB   0.1 mg Log in to see 29至35个工作日
¥4,590.71
详细
非结合性 IHC (p), WB Anti-CCR4 antibody, Western blotting Lane 1: CEM Cell Lysate Lane 2: JURKAT Cell Lysate Lane 3: HELA Cell Lysate Anti-CCR4 antibody, IHC(P) IHC(P): Human Tonsil Tissue 100 μg Log in to see 26至32个工作日
¥2,560.58
详细
小鼠 非结合性 WB Anti-CCR4 antibody, Western blotting All lanes: Anti CCR4  at 0.5ug/ml Lane 1: Rat Thymus Tissue Lysate at 50ug Lane 2: Rat Spleen Tissue Lysate at 50ug Lane 3: HEPA Whole Cell Lysate at 40ug Predicted bind size: 41KD Observed bind size: 41KD 100 μg Log in to see 26至32个工作日
¥2,560.58
详细

通过反应活性、应用领域、克隆类型和共轭标记 CCR4 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-CCR4 抗体

  1. Human Monoclonal CCR4 Primary Antibody for FACS - ABIN4899090 : Aruga, Takeshita, Kotera, Okuyama, Matsushita, Ohta, Takeda, Yamamoto: Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2013 (PubMed)
    Show all 12 references for 4899090

  2. Human Monoclonal CCR4 Primary Antibody for FACS - ABIN4895504 : Aruga, Takeshita, Kotera, Okuyama, Matsushita, Ohta, Takeda, Yamamoto: Phase I clinical trial of multiple-peptide vaccination for patients with advanced biliary tract cancer. in Journal of translational medicine 2014 (PubMed)
    Show all 11 references for 4895504

  3. Human Monoclonal CCR4 Primary Antibody for FACS - ABIN4895501 : James, Gates, LaFond, Yamamoto, Ni, Mai, Gersuk, OBrien, Nguyen, Zeitner, Lanteri, Norris, Chaussabel, Malhotra, Kwok: Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome. in PLoS pathogens 2016 (PubMed)
    Show all 7 references for 4895501

  4. Human Polyclonal CCR4 Primary Antibody for ICC, FACS - ABIN152140 : Power, Meyer, Nemeth, Bacon, Hoogewerf, Proudfoot, Wells: Molecular cloning and functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line. in The Journal of biological chemistry 1995 (PubMed)
    Show all 6 references for 152140

  5. Cow (Bovine) Polyclonal CCR4 Primary Antibody for EIA, IHC (fro) - ABIN492852 : Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003 (PubMed)
    Show all 3 references for 492852

  6. Human Monoclonal CCR4 Primary Antibody for FACS - ABIN4895497 : Antonelli, Mahnke, Hodge, Porter, Barber, DerSimonian, Greenwald, Roby, Mican, Sher, Roederer, Sereti: Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome. in Blood 2010 (PubMed)
    Show all 3 references for 4895497

  7. Cow (Bovine) Polyclonal CCR4 Primary Antibody for WB - ABIN2792190 : Nakayama, Hieshima, Arao, Jin, Nagakubo, Shirakawa, Yamada, Fujii, Oiso, Kawada, Nishio, Yoshie: Aberrant expression of Fra-2 promotes CCR4 expression and cell proliferation in adult T-cell leukemia. in Oncogene 2008 (PubMed)

  8. Human Polyclonal CCR4 Primary Antibody for IF (p), IHC (p) - ABIN738666 : Ge, Li, Jiang, You, Liu, Zhong, Huang, Xing: Integration of nondegradable polystyrene and degradable gelatin in a core-sheath nanofibrous patch for pelvic reconstruction. in International journal of nanomedicine 2015 (PubMed)

更多抗CCR4的相互作用对抗体

Mouse (Murine) Chemokine (C-C Motif) Receptor 4 (CCR4) interaction partners

  1. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer

  2. CCR4 is critically involved in regional lymph node dendritic cell-Th17 cell interactions that are necessary for Th17 cell-mediated induction of antitumor CD8 (显示 CD8A 抗体)+ effector T cells in mice bearing B16 melanoma.

  3. CCR4 is involved in immunosuppression after severe sepsis and suggest that CCR4+ Regulatory T Cells negatively modulate the short and long-term immune responses.

  4. CCL22 (显示 CCL22 PLURAL_@7566@) was localised mainly on the cell surface and or in the cytoplasm. Within sections of omental milky spot micrometastases, CCR4 was recognised on or in gastric cancer cells, constituent cells milky spots, blood cells and blood endothelial cells

  5. CCR4 is involved in regulating negative selection of polyclonal and T cell receptor (TCR) transgenic thymocytes

  6. results show that the IL-4 (显示 IL4 PLURAL_@7566@)/CCL22 (显示 CCL22 PLURAL_@7566@)/CCR4 axis is involved in the migration of Tregs to osteolytic lesion sites, and attenuates development of lesions by inhibiting inflammatory migration and the production of proinflammatory and osteoclastogenic mediators

  7. These data have uncovered a novel role of core components of the Ccr4-Not complex as regulators of transition from partial to genuine induced pluripotent stem cells.

  8. that effective engagement of CCR4 by CCL17 (显示 CCL17 抗体) involves two distinct binding domains and interaction with both is required for signaling

  9. NF-kappaB (显示 NFKB1 PLURAL_@7566@) signaling pathway was involved in the asthmatic change induced by CKLF1, among which CCR4 might play a crucial role

  10. CCR4-expressing Th2cells play a critical role in the pathogenesis of bronchial asthma by producing Th2 cytokines.

Human Chemokine (C-C Motif) Receptor 4 (CCR4) interaction partners

  1. Chemokine (显示 CCL1 抗体) receptors CCR3 (显示 CCR3 抗体) and CCR4, and the mucosa specific chemokine (显示 CCL1 抗体) CCL28 (显示 ENC1 抗体) have predominant roles in oral wound healing by increasing human gingiva fibroblast proliferation, migration, and the secretion of IL-6 (显示 IL6 抗体) and HGF (显示 HGF 抗体) and reducing the secretion of TIMP-1 (显示 TIMP1 抗体).

  2. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer

  3. The percentage of CXCR3 (显示 CXCR3 抗体)(+) CD4 (显示 CD4 抗体)(+) TEM (显示 CYLD 抗体) cells negatively correlated with the severity of the cutaneous disease in psoriasis patients. Importantly CLA (显示 SELPLG 抗体)(+) CD4 (显示 CD4 抗体)(+) TCM cells expressing CCR6 (显示 CCR6 抗体)(+) or CCR4(+)CXCR3 (显示 CXCR3 抗体)(+) negatively correlated with psoriasis severity suggesting recruitment to the skin compartment.

  4. Case Report: CCR4+ T-cell depletion by mogamulizumab treatment of adult T-cell leukaemia/lymphoma results in CD8 (显示 CD8A 抗体)-positive T-cell mediated dermatitis.

  5. CCL22 (显示 CCL22 PLURAL_@7566@)-specific antibodies reveal that engagement of two distinct binding domains on CCL22 (显示 CCL22 PLURAL_@7566@) is required for CCR4-mediated function.

  6. CCR4 mutation is an important determinant of the clinical course in ATLL cases, and that NS and FS mutations of CCR4 behave differently with respect to ATLL pathophysiology.

  7. Distinctive Treg associated CCR4-CCL22 (显示 CCL22 抗体) expression profile with altered frequency of Th17/Treg cell in the immunopathogenesis of Pemphigus Vulgaris (显示 DSG3 抗体).

  8. Data show that CCR4 was over-expressed in lymph node-negative human gastric cancer tissues and suggest its involvement in promoting tumor invasion probably, through up-regulation of MMP9 (显示 MMP9 抗体).

  9. CCR4 C1014T and CCL22 (显示 CCL22 抗体) C16A genetic variations were neither associated with the risk, nor with the progression of colorectal cancer in Iranian population

  10. Higher percentages of CCR4+ CD4 (显示 CD4 抗体) TEM (显示 CYLD 抗体) cells in acute RSV infection were accompanied with higher percentages of CXCR3 (显示 CXCR3 抗体)+ CD8 (显示 CD8A 抗体) TEM (显示 CYLD 抗体) cells, whereas the development of long-lived memory CXCR3 (显示 CXCR3 抗体)+ CD4 (显示 CD4 抗体) and CD8 (显示 CD8A 抗体) TCM cells seems to be compromised

CCR4 抗原简介

蛋白简介

The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Gene names and symbols associated with CCR4

  • chemokine (C-C motif) receptor 4 (CCR4) 抗体
  • CCR4-NOT transcription complex, subunit 6 (Cnot6) 抗体
  • chemokine (C-C motif) receptor 4 (Ccr4) 抗体
  • A230103N10Rik 抗体
  • AA407540 抗体
  • AW456442 抗体
  • C-C CKR-4 抗体
  • CC-CKR-4 抗体
  • CCR4 抗体
  • CD194 抗体
  • CHEMR1 抗体
  • ChemR13 抗体
  • CKR4 抗体
  • Cmkbr4 抗体
  • HGCN:14099 抗体
  • K5-5 抗体
  • LESTR 抗体
  • RGD1310783 抗体
  • Sdf1r 抗体

Protein level used designations for CCR4

chemokine (C-C motif) receptor 4 , C-C chemokine receptor type 4-like , c-C chemokine receptor type 4-like , CCR4-NOT transcription complex subunit 6 , carbon catabolite repressor protein 4 homolog , cytoplasmic deadenylase , C-C CKR-4 , C-C chemokine receptor type 4 , CCR-4 , chemokine (C-C) receptor 4 , CC chemokine receptor 4 , CC-CKR-4 , fusin , leukocyte-expressed seven-transmembrane-domain receptor , C-C chemokine receptor 4

GENE ID SPECIES
100397096 Callithrix jacchus
100445664 Pongo abelii
100585668 Nomascus leucogenys
104625 Mus musculus
287249 Rattus norvegicus
1233 Homo sapiens
403541 Canis lupus familiaris
408019 Bos taurus
12773 Mus musculus
171054 Rattus norvegicus
anti-CCR4 (CCR4) 抗体 精选生产商
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