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Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. 再加上，我们可以发CCR10 抗体 (167) 和 CCR10 蛋白 (4)和数多这个蛋白质的别的产品。
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study found that the inflammatory chemokine (显示 CCL1 ELISA试剂盒) CCL5 (显示 CCL5 ELISA试剂盒) is mostly retained (75%) during the resolution of zymosan A peritonitis in mice; CCL5 (显示 CCL5 ELISA试剂盒) exerts a novel proresolving role on macrophages when acting in concert with apoptotic PMN (显示 TBCE ELISA试剂盒)-expressed D6.
this study shows that losartan and dexamethasone may suppress inflammatory responses in IgA nephropathy by inhibiting CCR10 expression in Th22 cells
Further examination revealed that proximity of pro-lymphangiogenic macrophages to developing lymphatic vessel surfaces is increased in ACKR2-deficient mice and reduced in CCR2-deficient mice.
some cells, including plasmacytoid dendritic cells, can express both CCR2 (显示 CCR2 ELISA试剂盒) and ACKR2; that Ly6C(high) monocytes have particularly strong CCL2 (显示 CCL2 ELISA试剂盒)-scavenging potential in vitro and in vivo; and that CCR2 (显示 CCR2 ELISA试剂盒) is a much more effective CCL2 (显示 CCL2 ELISA试剂盒) scavenger than ACKR2.
Our in vivo analysis demonstrated that uniform expression of Ccr10 on MSCs and alteration of Ccl27 (显示 CCL27 ELISA试剂盒) level in the skin enhance extravasation of stem cells from circulation and facilitate their migration within cutaneous tissue
Chemokine (显示 CCL1 ELISA试剂盒) decoy receptor D6 limits CC-chemokine (显示 CCL1 ELISA试剂盒)-dependent pathogenic inflammation and is required for adequate cardiac remodeling after myocardial infarction.
control of CCR2 ligands by D6 regulates the traffic of Ly6C(high) monocytes and controls their immunosuppressive potential.
D6, by suppressing inflammatory chemokine (显示 CCL1 ELISA试剂盒) binding to lymphatic surfaces, and thereby preventing inflammatory leukocyte adherence, is a regulator of lymphatic function and a contributor to the integration of innate and adaptive immune responses.
identify novel D6(active) B1-cell subsets, including those we term B1d, which lack CD5 (显示 CD5 ELISA试剂盒) and CD11b (显示 ITGAM ELISA试剂盒) but exhibit typical B1-cell properties, including spontaneous ex vivo production of IgM (显示 CD40LG ELISA试剂盒), IL-10 (显示 IL10 ELISA试剂盒), and anti-phosphorylcholine antibody
These findings provide definite evidence that CCR10 is important in skin intraepithelial Vgamma3(+) T lymphocyte development
CCL27 (显示 CCL27 ELISA试剂盒) drives baseline recruitment of Herpes simplex virus-specific CD8 (显示 CD8A ELISA试剂盒) T cells expressing CCR10, while interferon (显示 IFNA ELISA试剂盒)-responsive CXCR3 (显示 CXCR3 ELISA试剂盒) ligands recruit additional cells in response to virus-driven inflammation.
Findings support the notion that CCR10 and its ligand CCL27 (显示 CCL27 ELISA试剂盒) may contribute to the skin infiltration of malignant T-cells in mycosis fungoides and adult T-cell leukemia/lymphoma.
low CCL27 (显示 CCL27 ELISA试剂盒)/CCR10 and CXCL12 (显示 CXCL12 ELISA试剂盒)/CXCR4 (显示 CXCR4 ELISA试剂盒) intratumoral mRNA ratios are associated with melanoma progression
CCR7 (显示 CCR7 ELISA试剂盒) overexpression correlated with expression of metallothionein (显示 MT ELISA试剂盒), while CCR10 was associated with cerebral metastases. CCR7 (显示 CCR7 ELISA试剂盒) and CCR10 overexpressions were associated with a worse outcome independent of Breslow's tumor thickness and Clark level.
unlike blood plasmacytoid dendritic cells (pDCs), a subset of tonsil pDCs express functional CCR6 (显示 CCR6 ELISA试剂盒) and CCR10, and their respective ligands CCL20 (显示 CCL20 ELISA试剂盒) and CCL27 (显示 CCL27 ELISA试剂盒) are detected in inflamed epithelia
The high fraction of circulating IgA+ and IgG+ B cells expressing CCR9 (显示 CCR9 ELISA试剂盒) and CCR10 in the first months of life indicates activation of naive B cells in the gut (显示 GUSB ELISA试剂盒), coinciding with bacterial colonization.
TLR2 ligands induce CCR9 and CCR10 expression by circulating B-cells and increase their chemotaxis. TLR2 stimulation also induced J chain and IgA production demonstrating the induction of mucosal-like antibody secreting cells.
CCR10 and its ligand CCL27 (显示 CCL27 ELISA试剂盒) may contribute to the skin infiltration of malignant T-cells in cutaneous T-cell lymphoma.
gene expression of CCR10 was increased by recombinant ANXA1 (显示 ANXA1 ELISA试剂盒) and the N-terminal ANXA1 (显示 ANXA1 ELISA试剂盒) peptide
CCR10-CTACK/CCL27 (显示 CCL27 ELISA试剂盒) interactions between circulating T cells and keratinocytes would seem to play an important role in the pathophysiology of mycosis fungoides.
Study showed bovine CCL28 mediating cellular chemotaxis via CCR10 chemokine receptor.
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues\; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27\; MIM 604833)\; CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002
CC chemokine receptor 10
, chemokine C-C motif receptor 10
, C-C chemokine receptor D6
, D6 beta-chemokine receptor
, chemokine binding protein 2
, chemokine-binding protein 2
, chemokine-binding protein D6
, C-C CKR-10
, C-C chemokine receptor type 10
, G protein-coupled receptor 2
, G-protein coupled receptor 2
, chemokine C-C receptor 9