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CCL28 belongs to the subfamily of small cytokine CC genes. 再加上，我们可以发CCL28 抗体 (89) 和 CCL28 试剂盒 (23)和数多这个蛋白质的别的产品。
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Results identified chemotactic and antimicrobial properties of bCCL28 indicating that this chemokine (显示 CCL1 蛋白) may contribute to immune protection of the mammary gland, and the resolution or prevention of bovine mastitis.
CCL28 was absent in saliva of primary Sjogren's syndrome patients. This finding did not correlate with salivary IgA levels.
disease severity of atopic dermatitis in children is not correlated to the level of CCL28, but rather related to that of total IgE
CCL28 (显示 ENC1 蛋白)-CCR3 (显示 CCR3 蛋白) interactions are involved in the homeostatic trafficking of CD4 (显示 CD4 蛋白)(+) T cells to the upper airways.
High CCL28 (显示 ENC1 蛋白) gene methylation is associated with gastric tumor aggressiveness.
CCL28 (显示 ENC1 蛋白) is a potent growth-promoting factor with the ability to support the in vitro and in vivo functional properties of cultured human hematopoietic cells.
These results indicate a role for IL-17A in the human lung by enhancing the expression of CCL28 and hence driving the recruitment of IgE-secreting B cells.
tumour hypoxia promotes the recruitment of regulatory T (T(reg (显示 EXTL3 蛋白))) cells through induction of expression of the chemokine (显示 CCL1 蛋白) CC-chemokine ligand 28 (CCL28), which, in turn, promotes tumour tolerance and angiogenesis
CCL28 (显示 ENC1 蛋白) may play dual roles in mucosal immunity as a chemoatt (显示 CCL1 蛋白)ractant for cells expressing CCR10 (显示 CCR10 蛋白) and/or CCR3 (显示 CCR3 蛋白) such as plasma cells and also as a broad-spectrum antimicrobial protein secreted into low-salt body fluids.
CCR10 and its mucosal epithelial ligand CCL28 have roles in the migration of circulating IgA plasmablasts
CCL28 (显示 ENC1 蛋白) produced by keratinocytes is mediated by different signal pathways from CCL27 (显示 CCL27 蛋白), and both CCL27 (显示 CCL27 蛋白) and CCL28 (显示 ENC1 蛋白) are involved in the pathogenesis of inflammatory skin diseases.
Mucosae associated-epithelial chemokine (MEC/CCL28) cloned from porcine salivary gland and colon tissues consisted of an open reading frame (ORF) of 384-bp coding for 127 amino-acids protein with 22 residues signal sequence.
Plasmid codelivery of murine CCL19 (显示 CCL19 蛋白) and CCL28 enhanced Ag-specific systemic and mucosal Ab responses to HIV-1 gp140, augmented balanced Th1 (显示 HAND1 蛋白)/Th2 responses, and increased lymphocyte subsets in various lymphoid tissues.
These data suggest that CCL28 could be useful in enhancing the IgA immune response that will likely play a pivotal role in prophylactic HIV vaccines.
tumour hypoxia promotes the recruitment of regulatory T (T(reg (显示 KCNH2 蛋白))) cells through induction of expression of the chemokine (显示 CCL1 蛋白) CC-chemokine ligand 28 (CCL28), which, in turn, promotes tumour tolerance and angiogenesis
demonstrate that interactions between the antimicrobial C-terminus of CCL28 with an appropriate CC chemokine (显示 CCL1 蛋白) N-terminal domain is important for the full antimicrobial activity of CCL28.
CCL28 has dual functions in mucosal immunity as a chemokine (显示 CCL1 蛋白) attracting cells expressing CCR10 (显示 CCR10 蛋白) and/or CCR3 (显示 CCR3 蛋白) and also as an apically secreted molecule with a potent antimicrobial activity against a broad spectrum of microbes.
MEC attracts IgA- but not IgG- or IgM-producing plasmablasts from both intestinal and nonintestinal lymphoid and effector tissues, including the intestines, lungs, and lymph nodes draining the bronchopulmonary tree and oral cavity.
Epithelial cells and venular endothelium of both small intestine and colon are positive for CCL28; CCL28 plays a direct role in intestinal homing of IgA antibody-secreting cells by mediating their extravasation into intestinal lamina propria.
CCL28 is a key regulator of IgA ASC accumulation in the mammary gland and thus controls the passive transfer of IgA antibodies from mother to infant.
CCL28 appears to play a role in regulating eosinophil recruitment to peribronchial regions of the lung possibly by coordinated temporal production with eotaxin
CCL28 mediates mucosal immunity in HIV exposure and infection
This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs.
C-C motif chemokine 28
, CC chemokine CCL28
, chemokine ligand 28
, chemokine CCL28/MEC
, chemokine (C-C motif) ligand 28
, ectodermal-neural cortex (with BTB-like domain)
, ectoderm neural cortex related-3
, chemokine (C-C motif) ligand 28 splice variant chi
, mucosae-associated epithelial chemokine
, small inducible cytokine A28
, small inducible cytokine subfamily A (Cys-Cys), member 28
, small-inducible cytokine A28
, chemokine CCL28
, mucosae-associated epithelial chemokine CCL28
, CC chemokine ligand 28