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CCL23 is one of several cytokine genes clustered on the q-arm of chromosome 17. 再加上，我们可以发Chemokine (C-C Motif) Ligand 23 蛋白 (39) 和 Chemokine (C-C Motif) Ligand 23 试剂盒 (38)和数多这个蛋白质的别的产品。
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Human Monoclonal CCL23 Primary Antibody for CyTOF, FACS - ABIN4899629
Novak, Müller, Harrer, Günther, Carballido, Woisetschläger: CCL23 expression is induced by IL-4 in a STAT6-dependent fashion. in Journal of immunology (Baltimore, Md. : 1950) 2007
CCL23 is posttranslationally modified by trypsin-like serine proteases and CCL23(47-117) might be a major active form of CCL23 in nasal polyps with chronic rhinosinusitis.
The coexistence of diabetes and oxidative stress independently affected CCL23 levels, while the presence of Cardiovascular disease and inflammation had no impact on its concentrations.
ADAMTS 8 (显示 ADAMTS8 抗体), CCL23, and TNFSF15 (显示 TNFSF15 抗体) are implicated in anti-angiogenic activities
Data show CCL23 stimulates chemotaxis of human THP-1 (显示 GLI2 抗体) monocytes and enhances release of MMP-2 (显示 MMP2 抗体), and suggest it plays a role in atherogenesis.
Overproduction of CCL23 in nasal polyps might contribute to the pathogenesis of eosinophilic chronic rhinosinusitis with nasal polyps
Patients with systemic sclerosis who had elevated CCL23 levels had shorter disease duration, and a higher frequency of pulmonary arterial hypertension. Serum CCL23 level was increased in early phase of disease and could be a marker for disease activity.
Fresh eosinophils contained trace amounts of CCL23 protein. CCL23 was significantly released into the supernatant when the eosinophils were stimulated with GM-CSF (显示 CSF2 抗体) or IL-5 (显示 IL5 抗体) but not with IFN-gamma (显示 IFNG 抗体) or immobilized sIgA.
The role of KLF6 (显示 KLF6 抗体) and PPAR-gamma (显示 PPARG 抗体) in MIP-3alpha (显示 CCL20 抗体) transcriptional regulation, was determined.
CKbeta8- and CKbeta8-1-induced activation of ERK1/2 (显示 MAPK1/3 抗体) is mediated by the G(i)/G(o) protein, PLC (显示 HSPG2 抗体), and PKCdelta (显示 PKCd 抗体).
CKbeta8 transduces the chemotaxis signal through the G(i)/G(o) protein, phospholipase C (显示 PLC 抗体), protein kinase C delta (显示 PKCd 抗体) and NF-kappaB (显示 NFKB1 抗体).
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist at CC chemokine receptor 1. Two alternatively spliced variants encoding different active isoforms have been identified.
, macrophage inflammatory protein 3
, myeloid progenitor inhibitory factor 1
, C-C motif chemokine 23
, C6 beta-chemokine
, small inducible cytokine subfamily A (Cys-Cys), member 23
, chemokine CCL23/MPIF-1
, small inducible cytokine A23
, small-inducible cytokine A23