Chemokine (C-X-C Motif) Ligand 10 蛋白 (CXCL10)

CXCL10 encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. 再加上,我们可以发CXCL10 抗体 (341)CXCL10 试剂盒 (131)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
CXCL10 3627 P02778
CXCL10 15945 P17515
CXCL10 245920 P48973
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$4,744.22
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
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大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$4,744.22
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大肠杆菌(E. Coli) 小鼠 非结合性 25 μg Log in to see 10至12个工作日
$226.22
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大肠杆菌(E. Coli) Cow His tag,T7 tag 100 μg Log in to see 15至18个工作日
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大肠杆菌(E. Coli) 大鼠 His tag,T7 tag 100 μg Log in to see 15至18个工作日
$845.00
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大肠杆菌(E. Coli) His tag Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98), (full length) protein (His tag) 50 μg Log in to see 13至16个工作日
$242.00
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大肠杆菌(E. Coli) His tag 100 μg Log in to see 15至18个工作日
$1,280.00
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大肠杆菌(E. Coli) 非结合性 4 pack Log in to see 10至12个工作日
$95.24
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大肠杆菌(E. Coli) 非结合性   10 μg Log in to see 10至12个工作日
$113.10
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CXCL10 蛋白 by Origin and Source

Origin 在表达 标记
Human , , , , ,
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Mouse (Murine) ,
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Rat (Rattus) ,
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引用最多的CXCL10 蛋白

  1. Human CXCL10 Protein expressed in Escherichia coli (E. coli) - ABIN1305104 : Farber: Mig and IP-10: CXC chemokines that target lymphocytes. in Journal of leukocyte biology 1997 (PubMed)
    Show all 4 Pubmed References

更多Chemokine (C-X-C Motif) Ligand 10 (CXCL10)互动伙伴

Pig (Porcine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. a SNP in CXCL10 was significantly associated with percentage of lymphocyte in blood of 20-day-old pigs and with hematocrit and mean red cell volume in blood of 80-day-old pigs

  2. CXCL10 protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 (显示 CCL2 蛋白) mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.

  3. Authors identified chemokine (C-X-C motif) ligand 10 (CXCL10), also named interferon-gamma inducible protein-10 (IP-10), as a novel target gene of miR (显示 MYLIP 蛋白)-21.

  4. These in vitro and in vivo observations suggest that interferon-gamma inducible protein 10 (IP-10) may be a reliable biomarker for immune activity induced by CpG oligodeoxynucleotides in pigs.

  5. The swine CXCL10 gene contains four exons and three introns.

Human Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. In lipotoxic hepatocytes, MLK3 (显示 MAP3K11 蛋白) activates a MAPK (显示 MAPK1 蛋白) signaling cascade, resulting in the activating phosphorylation of STAT1 (显示 STAT1 蛋白), and CXCL10 transcriptional upregulation.

  2. Neuroendocrine-like cells promote the chemotaxis activity of tumor-associated macrophages (TAM (显示 CCNA1 蛋白)) via CXCL10 and CXCL11 (显示 CXCL11 蛋白).

  3. These results showed that the higher levels of CXCL10, CCL20 (显示 CCL20 蛋白) and CCL22 (显示 CCL22 蛋白) were associated with ischemic heart disease. The serum levels of chemokines may influence by the certain traditional risk factors of IHD and some studied SNPs, but did not influence by treatment and gender of patients.

  4. High CXCL10 expression is associated with clear-cell renal cell carcinoma (显示 MOK 蛋白).

  5. a massive and selective serum CXCL10 response in R. conorii-infected patients, likely reflecting release from infected endothelial cells characterized by infiltrating T cells and monocytes.

  6. The strongest OR was for CXCL8 (interleukin-8 (显示 IL8 蛋白)) in serum (96.8, 95% CI: 11.9-790.2). Of these 15 markers, 6 were also significantly elevated in serum from Chile (CCL20 (显示 CCL20 蛋白), C-reactive protein (显示 CRP 蛋白), CXCL8 (显示 IL8 蛋白), CXCL10, resistin (显示 RETN 蛋白), serum amyloid A).

  7. These findings elucidate an NFAT (显示 NFATC1 蛋白)-MAPK (显示 MAPK1 蛋白) signaling paradigm for induction of isletokine expression in beta-cells and reveal IP-10 as a primary therapeutic target to prevent beta-cell-induced inflammatory loss of graft function after islet cell transplantation.

  8. High urine CXCL10 level is associated with acute rejection in Histologically Stable Kidney transplant Recipients.

  9. IL-10 (显示 IL10 蛋白), IL-17 (显示 IL17A 蛋白) and IP-10 response to tubercular antigens act as potent discriminative markers for active tuberculosis among pulmonary tuberculosis suspects.

  10. The performance of IFNG (显示 IFNG 蛋白) release assays is robust despite variations in the incubation temperature between 37 degrees C and 39 degrees C for the diagnosis of latent tuberculosis infection.

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. In lipotoxic hepatocytes, MLK3 activates a MAPK (显示 MAPK1 蛋白) signaling cascade, resulting in the activating phosphorylation of STAT1 (显示 STAT1 蛋白), and CXCL10 transcriptional upregulation.

  2. These findings elucidate an NFAT (显示 NFATC1 蛋白)-MAPK (显示 MAPK1 蛋白) signaling paradigm for induction of isletokine expression in beta-cells and reveal IP-10 as a primary therapeutic target to prevent beta-cell-induced inflammatory loss of graft function after islet cell transplantation.

  3. A novel function of CXCL10 in mediating monocyte production of proinflammatory cytokines in inflammatory bowel diseases has been described.

  4. this study shows that poly I:C treated PAR-1 (显示 MARK2 蛋白)-/- mice given the thrombin (显示 F2 蛋白) inhibitor dabigatran etexilate exhibited less IFNbeta and CXCL10 expression in the spleen and plasma

  5. ATF3 (显示 ATF3 蛋白)-KO mice escape from PE-dependent maladaptive cardiac remodeling by suppressing the IFNgamma-CXCL10-CXCR3 (显示 CXCR3 蛋白) axis at multiple levels.

  6. this study shows that neutrophils and NK cells act as important disease-promoting immune cells in experimental osteoarthritis and their functional interaction is promoted by the CXCL10/CXCR3 (显示 CXCR3 蛋白) axis

  7. CXCL10 chemokine (显示 CCL1 蛋白) levels correlate negatively with gremlin-1 (显示 GREM1 蛋白) levels in mouse and human lung.

  8. Increased CXCL10 expression led to decreased tumour burden and malignant ascites accumulation in the ID8 syngeneic murine model of HGSC.

  9. These findings demonstrate that the CXCL10/CXCR3 (显示 CXCR3 蛋白) chemokine (显示 CCL1 蛋白) pathway is critical in shaping CD8 (显示 CD8A 蛋白)(+) T cell immunity, locally within latently infected tissues, which protects against recurrent herpesvirus infection and disease.

  10. CXCL10 plays in the pathogenesis of recurrent Herpetic stromal keratitis, and that CXCL9 (显示 CXCL9 蛋白) displays its importance when CXCL10 is absent.

Cow (Bovine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. These results demonstrated that bovine colonic cells seem capable to respond to E. bovis merozoite I infection by the upregulation of CXCL10 and GM-CSF (显示 CSF2 蛋白) gene transcription.

  2. IL-17A (显示 IL17A 蛋白) was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.

蛋白简介CXCL10

蛋白简介

This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression.

Gene names and symbols associated with CXCL10

  • C-X-C motif chemokine ligand 10 (CXCL10)
  • C-X-C motif chemokine 10 (cxl10)
  • chemokine (C-X-C motif) ligand 10 (Cxcl10)
  • C-X-C motif chemokine ligand 10 (Cxcl10)
  • C7 蛋白
  • CRG-2 蛋白
  • CXCL10 蛋白
  • gIP-10 蛋白
  • Ifi10 蛋白
  • INP10 蛋白
  • IP-10 蛋白
  • IP10 蛋白
  • mob-1 蛋白
  • Scyb10 蛋白

Protein level used designations for CXCL10

chemokine (C-X-C motif) ligand 10 , C-X-C motif chemokine 10 , chemokine CXC-like protein , chemokine C-X-C motif ligand 10 , C-X-C motif chemokine 10-like protein , 10 kDa interferon gamma-induced protein , gamma IP10 , gamma-IP10 , interferon-inducible cytokine IP-10 , protein 10 from interferon (gamma)-induced cell line , small inducible cytokine subfamily B (Cys-X-Cys), member 10 , small-inducible cytokine B10 , interferon activated gene 10 , interferon-gamma induced protein CRG-2 , interferon-gamma-induced protein CRG-2 , small inducible cytokine B subfamily (Cys-X-Cys), member 10 , interferon-inducible protein 10 , protein Mob-1 , small inducible cytokine B subfamily (Cys-X-Cys) member 10 , gamma interferon inducible protein 10 , CXC chemokine ligand 10 , interferon-gamma-inducible protein 10 , interferon-gamma-inducible protein-10 , 10 kDa interferon-gamma-induced protein , 10 kDa interferon-gamma-inducible protein CXCL10 , IP-10 , small inducible cytokine B10

GENE ID SPECIES
461242 Pan troglodytes
494019 Sus scrofa
100050993 Equus caballus
100195999 Salmo salar
3627 Homo sapiens
15945 Mus musculus
245920 Rattus norvegicus
615107 Bos taurus
478432 Canis lupus familiaris
442997 Ovis aries
574243 Macaca mulatta
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