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anti-Ceramide Synthase 2 (CERS2) 抗体

CERS2 encodes a protein that has sequence similarity to yeast longevity assurance gene 1. 再加上,我们可以发Ceramide Synthase 2 蛋白 (5)Ceramide Synthase 2 试剂盒 (1)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CERS2 29956 Q96G23
CERS2 76893 Q924Z4
CERS2 310667  

antibodies-online.cn销售最多的anti-Ceramide Synthase 2 抗体

Showing 10 out of 54 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB 100 μL Log in to see 24至29个工作日
¥3,074.65
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Cow 非结合性 IHC, WB 100 μL Log in to see 24至29个工作日
¥3,074.65
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Cow 非结合性 WB WB Suggested Anti-LASS2 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 24至29个工作日
¥3,074.65
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非结合性 WB 0.1 mg Log in to see 29至35个工作日
¥4,187.20
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小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (67.32 KDa) . 200 μL Log in to see 29至34个工作日
¥3,169.73
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小鼠 非结合性 WB Western Blot analysis of LASS2 expression in transfected 293T cell line by LASS2 MaxPab polyclonal antibody.Lane 1: LASS2 transfected lysate(41.8 KDa).Lane 2: Non-transfected lysate. LASS2 MaxPab polyclonal antibody. Western Blot analysis of LASS2 expression in human placenta. 50 μg Log in to see 29至34个工作日
¥3,169.73
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豚鼠 非结合性 IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with LASS2 antibody ABIN462181 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Liver (formalin-fixed, paraffin-embedded) stained with LASS2 antibody ABIN462181 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 29至35个工作日
¥6,705.77
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非结合性 ELISA, WB 50 μg Log in to see 24至29个工作日
¥4,312.06
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非结合性 ELISA, WB 50 μg Log in to see 24至29个工作日
¥4,312.06
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Bat 非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
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通过反应活性、应用领域、克隆类型和共轭标记 CERS2 抗体

特性 应用范围 宿主 克隆类型 标记
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Mouse (Murine) ,


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Rat (Rattus) ,


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引用最多的anti-Ceramide Synthase 2 抗体

  1. Human Polyclonal CERS2 Primary Antibody for WB - ABIN265218 : Becker, Wang-Eckhardt, Yaghootfam, Gieselmann, Eckhardt: Differential expression of (dihydro)ceramide synthases in mouse brain: oligodendrocyte-specific expression of CerS2/Lass2. in Histochemistry and cell biology 2008 (PubMed)
    Show all 2 references for ABIN265218

  2. Human Monoclonal CERS2 Primary Antibody for ELISA, WB - ABIN526190 : Separovic, Breen, Joseph, Bielawski, Pierce, VAN Buren, Gudz: Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells. in Anticancer research 2012 (PubMed)
    Show all 2 references for ABIN526190

  3. Cow (Bovine) Polyclonal CERS2 Primary Antibody for IHC, WB - ABIN2781175 : Laviad, Albee, Pankova-Kholmyansky, Epstein, Park, Merrill, Futerman: Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. in The Journal of biological chemistry 2008 (PubMed)

  4. Human Polyclonal CERS2 Primary Antibody for WB - ABIN526188 : Jensen, Calvert, Volpert, Kouri, Hurley, Luciano, Wu, Chalastanis, Futerman, Stegh: Bcl2L13 is a ceramide synthase inhibitor in glioblastoma. in Proceedings of the National Academy of Sciences of the United States of America 2014 (PubMed)

更多抗Ceramide Synthase 2的相互作用对抗体

Human Ceramide Synthase 2 (CERS2) interaction partners

  1. ASGR1 (显示 ASGR1 抗体) can inhibit the activity of V-ATPase (显示 ATP6V1H 抗体) by interacting with LASS2, thereby suppressing the metastatic potential of hepatoma cells.

  2. Data show that 1-acylglycerol-3-phosphate O-acyltransferase 9 (AGPAT9 (显示 AGPAT9 抗体)) inhibit cell growth by regulating expression of KLF4 (显示 KLF4 抗体)/LASS2/V-ATPase (显示 ATP6V1H 抗体) proteins in breast cancer.

  3. these results indicate that miR (显示 MLXIP 抗体)-9 upregulation might be associated with malignant phenotype of bladder cancer. miR (显示 MLXIP 抗体)-9 promotes chemoresistance of bladder cancer cells by target LASS2.

  4. Data show that CERS2 expression was markedly different between various breast cancer cells and inversely correlated with cell invasion.

  5. silencing of TMSG1 increased V-ATPase (显示 ATP6V1H 抗体) activity, decreased extracellular pH and in turn the activation of secreted MMP-2 (显示 MMP2 抗体), which ultimately promoted metastasis capacity of breast cancer cell.

  6. Results confirmed that TMSG1 is a potential metastasis suppressor gene, and suggested that the mechanism involved the induction of apoptosis and inhibition of cell proliferation via a caspase (显示 CASP3 抗体)-dependent mitochondrial pathway.

  7. the vacuolar ATPase (V-ATPase (显示 DNAH8 抗体)) activity and extracellular hydrogen ion concentration were significantly decreased and the activity of secreted matrix metalloproteinase-2 (MMP-2 (显示 MMP2 抗体)) was downregulated in MCF-7 cells overexpressing LASS2/TMSG1

  8. the inhibitory effect of the LASS2 on growth, invasion and metastasis of prostate cancer cells

  9. Co-expression of CerS2 with CerS4 (显示 CERS4 抗体)/CerS6 (显示 CERS6 抗体) reversed the inhibitory effect of long chain ceramides on cell proliferation and the induction of apoptosis. we detected no effect on cell proliferation.

  10. expression and role of ceramide synthase-2 in the lung

Mouse (Murine) Ceramide Synthase 2 (CERS2) interaction partners

  1. this study shows that Cers2 limits the levels of S1P (显示 S1PR1 抗体) in thymus and blood to maintain functional S1P (显示 S1PR1 抗体) gradients that mediate thymocyte emigration into the circulation

  2. that only LCBs, the substrates common for all of the CerS isoforms, but not ceramides and complex sphingolipids, were restored to the wild-type levels in the Cers2-rescued Cers1 (显示 CERS1 抗体) mutant mouse brains.

  3. CerS1 (显示 CERS1 抗体), -2, and -6 are hyperacetylated in the mitochondria of SIRT3 (显示 SIRT3 抗体)-null mice.

  4. Haploinsufficiency for this enzyme altered the pattern of ceramide acylation in the liver without affecting total ceramide levels, replacing very-long-chain ceramides with long-chain C16-ceramides.

  5. Development of pheochromocytoma in ceramide synthase 2 null mice

  6. our data strongly indicate that G-CSF (显示 CSF3 抗体)-induced CXCR2 (显示 CXCR2 抗体) expression is regulated in a CerS2-dependent manner and that CerS2 thereby promotes the migration of neutrophils, thus, contributing to inflammation and the development of EAE and MS.

  7. Data indicate that the augmented rate of death of ceramide synthase 2 (CerS2) null mice is due to elevated levels of tumor necrosis factor alpha (TNFalpha (显示 TNF 抗体)) secretion as a result of enhanced activity of TNFalpha (显示 TNF 抗体)-converting enzyme (TACE (显示 ADAM17 抗体)).

  8. CerS2-deficient kidneys were completely depleted of phytosphingosine-containing cortical sulfatides without any compensatio

  9. we first report that Lass2 deficiency caused the downregulation of miR (显示 MLXIP 抗体)-694 and the upregulation of its target gene Tnfaip3 (显示 TNFAIP3 抗体) in vivo in mice, which may be related to a high risk of occurrence of hepatocellular carcinoma

  10. The identification of specific cell types in which CerS2 protein is expressed is prerequisite to further mechanistic characterization of phenotypic abnormalities exhibited by CerS2-deficient mice.

Ceramide Synthase 2 (CERS2) 抗原简介

蛋白简介

This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.

Gene names and symbols associated with anti-Ceramide Synthase 2 (CERS2) 抗体

  • ceramide synthase 2 (LASS2) 抗体
  • ceramide synthase 2 (CERS2) 抗体
  • ceramide synthase 2 (Cers2) 抗体
  • 0610013I17Rik 抗体
  • AI225939 抗体
  • L3 抗体
  • Lass2 抗体
  • SP260 抗体
  • TMSG1 抗体
  • TRH3 抗体

Protein level used designations for anti-Ceramide Synthase 2 (CERS2) 抗体

LAG1 homolog, ceramide synthase 2 , LAG1 longevity assurance 2 , longevity assurance (LAG1, S. cerevisiae) homolog 2 , tumor metastasis-suppressor gene 1 protein , LAG1 longevity assurance homolog 2 , TRAM homolog 3 , longevity assurance homolog 2 , translocating chain-associating membrane protein homolog 3

GENE ID SPECIES
100055037 Equus caballus
29956 Homo sapiens
483187 Canis lupus familiaris
539223 Bos taurus
76893 Mus musculus
310667 Rattus norvegicus
100156737 Sus scrofa
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