anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) 抗体

The protein encoded by CDC37 is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. 再加上,我们可以发CDC37 蛋白 (22)CDC37 试剂盒 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CDC37 11140 Q16543
CDC37 12539 Q61081
CDC37 114562 Q63692

antibodies-online.cn销售最多的anti-CDC37 抗体

Showing 10 out of 147 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 ELISA, WB Western blot analysis of extracts from NIH-3T3/HT-29/RAW264.7 cells, using p50 CDC37 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
小鼠 非结合性 IF, IP, IHC, WB Western blot analysis of CDC37 on human endothelial lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of CDC37. WI38 50 μg Log in to see 24至30个工作日
¥1,258.37
详细
非结合性 WB Observed bind size: 44KD 100 μg Log in to see 26至32个工作日
¥2,919.96
详细
非结合性 IF, IHC (p), WB 0.1 mg Log in to see 29至35个工作日
¥3,884.46
详细
非结合性 WB Anti- Cdc37 antibody, Western blotting All lanes: Anti Cdc37 at 0.5ug/ml Lane 1: JURKAT Whole Cell Lysate at 40ug Lane 2: 293T Whole Cell Lysate at 40ug Predicted bind size: 44KD Observed bind size: 44KD 100 μg Log in to see 26至32个工作日
¥2,560.58
详细
非结合性 IHC, ELISA, WB Western blot analysis of extracts from HuvEc cells, using CDC37 (Phospho-Ser13) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human placenta, using CDC37 (Phospho-Ser13) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
非结合性 ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: CDC37 Antibody [NBP1-80960] - Staining of human duodenum shows moderate cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: CDC37 Antibody [NBP1-80960] - Staining of human cell line A-431 shows positivity in cytoplasm. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
详细
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti CDC37 Polyclonal Antibody, Unconjugated (ABIN706481) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti CDC37 Polyclonal Antibody, Unconjugated (ABIN706481) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 5至7个工作日
¥2,610.23
详细
非结合性 IF, IHC, ELISA, WB Western blot analysis of extracts from MCF-7/COS7 cells, using CDC37 (Ab-13) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using CDC37 (Ab-13) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
非结合性 ELISA, IHC, WB 100 μL Log in to see 34至38个工作日
¥4,371.67
详细

通过反应活性、应用领域、克隆类型和共轭标记 CDC37 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-CDC37 抗体

  1. Dog (Canine) Monoclonal CDC37 Primary Antibody for IF, IP - ABIN968047 : Grammatikakis, Lin, Grammatikakis, Tsichlis, Cochran: p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function. in Molecular and cellular biology 1999 (PubMed)
    Show all 3 references for 968047

  2. Human Polyclonal CDC37 Primary Antibody for ELISA, WB - ABIN1534319 : Lamphere, Fiore, Xu, Brizuela, Keezer, Sardet, Draetta, Gyuris: Interaction between Cdc37 and Cdk4 in human cells. in Oncogene 1997 (PubMed)

  3. Human Polyclonal CDC37 Primary Antibody for ICC, IF - ABIN4296941 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

更多抗CDC37的相互作用对抗体

Fruit Fly (Drosophila melanogaster) Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) interaction partners

Human Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) interaction partners

  1. The results suggest a re-evaluation of the role of Cdc37 in the kinase lifecycle, and suggest that such interactions potentially allow kinases to more rapidly respond to key signals while simultaneously protecting unstable kinases from degradation and suppressing unwanted basal activity.

  2. Niclosamide ethanolamine disrupted the interaction between cell division cycle 37 and heat shock protein 90 (显示 HSP90 抗体) in hepatocellular carcinoma, reducing tumor growth.

  3. Cdc37 performs a quality control of protein kinases, including b-raf (显示 SNRPE 抗体), where induced conformational instability acts as a "flag" for Hsp90 (显示 HSP90 抗体) dependence and stable cochaperone association.

  4. Ulk1 (显示 ULK1 抗体) promoted the degradation of Hsp90 (显示 HSP90 抗体)-Cdc37 client kinases, resulting in increased cellular sensitivity to Hsp90 (显示 HSP90 抗体) inhibitors. Thus, our study provides evidence for an anti-proliferative role of Ulk1 (显示 ULK1 抗体) in response to Hsp90 (显示 HSP90 抗体) inhibition in cancer cells

  5. The authors find that the interaction between sB-Raf (显示 RAF1 抗体) and the Hsp90 chaperone (显示 HSP90 抗体) system is based on contacts with the M domain of Hsp90 (显示 HSP90 抗体), which contributes in forming the ternary complex with Cdc37 as long as the kinase is not stabilized by nucleotide.

  6. Apart from these distinct Cdc37/Hsp90 interfaces, binding of the B-Raf protein kinase to the cochaperone is conserved between mammals and nematodes.

  7. Suppressing expression of the cochaperone CDC37 in hepatocellular carcinoma cells inhibits cell cycle progression and cell growth.

  8. RIP3 (显示 RIPK3 抗体) activation following the induction of necroptosis requires the activity of an HSP90 (显示 HSP90 抗体) and CDC37 cochaperone complex.

  9. Correlation between PDZK1 (显示 PDZK1 抗体), Cdc37, Akt (显示 AKT1 抗体) and breast cancer malignancy: the role of PDZK1 (显示 PDZK1 抗体) in cell growth through Akt (显示 AKT1 抗体) stabilization by increasing and interacting with Cdc37

  10. The N-terminal tail serves as an intramolecular chaperone ensuring that CDC37 assumes one of two interconvertible states in a manner impacting the interaction of the client binding N-domain and the MC-domains, involved in dimerization and HSP90 (显示 HSP90 抗体) binding.

Mouse (Murine) Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) interaction partners

  1. Niclosamide ethanolamine disrupted the interaction between cell division cycle 37 and heat shock protein 90 (显示 HSP90 抗体) in hepatocellular carcinoma, reducing tumor growth.

  2. A series of tyrosine phosphorylation events, involving both p50(Cdc37) and Hsp90 (显示 HSP90 抗体), are minimally sufficient to provide directionality to the chaperone cycle.

  3. Hsp90 (显示 HSP90 抗体)-Cdc37 complex acta (显示 ACTC1 抗体) as an endogenous regulator of noncanonical p38alpha (显示 MAPK14 抗体) activity.

  4. CDC37 binds to Akt (显示 AKT1 抗体) and HSP90 (显示 HSP90 抗体) in the signal transduction pathway in human tumor cells

  5. The interaction between mouse Pem and Cdc37 homolog was then confirmed by glutathione S-transferase (显示 GSTa2 抗体) pull-down assay, and the possible interaction model was suggested.

  6. JAK1 (显示 JAK1 抗体)/2 are client proteins of Hsp90 alpha (显示 HSP90AA1 抗体) and beta; Hsp90 (显示 HSP90 抗体) and CDC37 play a critical role in types I and II interferon (显示 IFNA 抗体) pathways

  7. This growth inhibition is partially rescued by expression of ectopic Gli1 (显示 GLI1 抗体), suggesting that Fu may contribute to enhance Hh signaling activity in cancer cells.

Cow (Bovine) Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) interaction partners

  1. Cdc37 has a direct regulatory interaction with endothelial nitric oxide synthase (eNOS (显示 NOS3 抗体)) and may play an important role in mediating the eNOS (显示 NOS3 抗体) protein complex formation.

CDC37 抗原简介

蛋白简介

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

Gene names and symbols associated with CDC37

  • CG12019 gene product from transcript CG12019-RA (Cdc37) 抗体
  • cell division cycle 37 homolog (Cdc37) 抗体
  • Hsp90 co-chaperone Cdc37 (cdc37) 抗体
  • Hsp90 co-chaperone Cdc37 (AFUA_4G10010) 抗体
  • Cell cycle protein necessary for passage of START (CDC37) 抗体
  • cell division cycle 37 (CDC37) 抗体
  • cell division cycle 37 (Cdc37) 抗体
  • cell division cycle 37 homolog (S. cerevisiae) (CDC37) 抗体
  • Afu4g10010 抗体
  • cdc37 抗体
  • CG12019 抗体
  • CPDR-1 抗体
  • CPDR-2 抗体
  • Dmel\\CG12019 抗体
  • DROCPDR 抗体
  • E(sev)3B 抗体
  • p50 抗体
  • p50Cdc37 抗体

Protein level used designations for CDC37

CG12019-PA , Cdc37-PA , cdc37 protein , hsp90 co-chaperone Cdc37 , Hsp90 co-chaperone Cdc37 , hypothetical protein , CDC37 (cell division cycle 37, S. cerevisiae, homolog) , CDC37 cell division cycle 37 homolog , cell division cycle 37 homolog , hsp90 chaperone protein kinase-targeting subunit , CDC37 (cell division cycle 37 S. cerevisiae homolog) , p50Cdc37 , CDC37 cell division cycle 37 protein , CDC37 homolog , cell division cycle 37 protein , cell division cycle control protein 37

GENE ID SPECIES
38232 Drosophila melanogaster
724675 Apis mellifera
2541293 Schizosaccharomyces pombe 972h-
3509722 Aspergillus fumigatus Af293
3639210 Candida albicans SC5314
11140 Homo sapiens
12539 Mus musculus
114562 Rattus norvegicus
484955 Canis lupus familiaris
100141402 Sus scrofa
520883 Bos taurus
395430 Gallus gallus
anti-CDC37 (CDC37) 抗体 精选生产商
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