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CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. 再加上，我们可以发CDC20 蛋白 (6) 和 CDC20 试剂盒 (1)和数多这个蛋白质的别的产品。
Showing 10 out of 212 products:
Human Polyclonal CDC20 Primary Antibody for EIA, IP - ABIN117946
Jentsch, Pyrowolakis: Ubiquitin and its kin: how close are the family ties? in Trends in cell biology 2000
Show all 8 references for ABIN117946
Human Polyclonal CDC20 Primary Antibody for ICC, IF - ABIN252981
Di Fiore, Pines: How cyclin A destruction escapes the spindle assembly checkpoint. in The Journal of cell biology 2010
Show all 3 references for ABIN252981
Human Polyclonal CDC20 Primary Antibody for ICC, IF - ABIN252980
Ahlskog, Björk, Elsing, Aspelin, Kallio, Roos-Mattjus, Sistonen: Anaphase-promoting complex/cyclosome participates in the acute response to protein-damaging stress. in Molecular and cellular biology 2010
Show all 2 references for ABIN252980
Human Polyclonal CDC20 Primary Antibody for IP, WB - ABIN233786
Yamamuro, Kano, Naito: Functions of FZR1 and CDC20, activators of the anaphase-promoting complex, during meiotic maturation of swine oocytes. in Biology of reproduction 2008
Human Polyclonal CDC20 Primary Antibody for IHC, IHC (p) - ABIN4296835
Onul, Colvard, Paradise, Elseth, Vesper, Gouvas, Deliu, Garcia, Pestle, Radosevich: Application of immunohistochemical staining to detect antigen destruction as a measure of tissue damage. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2012
Cow (Bovine) Polyclonal CDC20 Primary Antibody for IHC, WB - ABIN2774602
Wolthuis, Clay-Farrace, van Zon, Yekezare, Koop, Ogink, Medema, Pines: Cdc20 and Cks direct the spindle checkpoint-independent destruction of cyclin A. in Molecular cell 2008
Human Polyclonal CDC20 Primary Antibody for ELISA, WB - ABIN1534317
Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006
These results provide novel insight into the mechanisms underlying the aberrant capability of NUP98 (显示 NUP98 抗体) oncoproteins to interact with APC (显示 APC 抗体)/C(Cdc20) and to interfere with its function.
In lung adenocarcinoma patients, overexpression of cell division cycle 20 was significantly associated with bigger primary tumor size, higher MKI67 (显示 MKI67 抗体) level, higher DNA ploidy level, and poor prognosis.
CDC20 may have a role in carcinoma of the breast, colon, endometrium, and prostate
Overexpression of Cdc20 may serve as an independent predictor for biochemical recurrence in patients of clinically localized prostate cancer undergoing laparoscopic radical prostatectomy without neoadjuvant therapy.
Results show that CYP1B1 (显示 CYP1B1 抗体) may promote renal cell carcinoma (显示 MOK 抗体) development by inducing CDC20 expression and inhibiting apoptosis through the down-regulation of DAPK1 (显示 DAPK1 抗体).
Study describes a positive feedback loop centred on cyclin A2 (显示 CCNA2 抗体)-Cdk2 (显示 CDK2 抗体) inhibition of interphase APC (显示 APC 抗体)/C-Cdc20 to allow further cyclin A2 (显示 CCNA2 抗体) accumulation and mitotic entry.
Bub1 (显示 BUB1 抗体)-Plk1 (显示 PLK1 抗体)-mediated phosphorylation of Cdc20 constitutes an anaphase-promoting complex or cyclosome-inhibitory mechanism that is parallel, but not redundant, to mitotic checkpoint (显示 BUB3 抗体) complex formation.
The presence of this segment correlates with SAC (显示 ADCY10 抗体) activity and efficient binding of CDC20 but not of MAD1 (显示 MXD1 抗体) to kinetochores.
These results suggest CDC20 is a critical regulator of TIC (显示 ARNTL 抗体) proliferation and survival, linking two key TIC (显示 ARNTL 抗体) nodes-FOXM1 (显示 FOXM1 抗体) and p21CIP1/WAF1 (显示 CDKN1A 抗体)-elucidating a potential point for therapeutic intervention.
CDC20 is essential for the in vivo tumorigenicity of glioblastoma stem-like cells. CDC20 is prognostic of overall survival in Proneural subtype glioblastoma patients.
Cdc20 auto-ubiquitylation does not play a major role in terminating Cdc20 activation.
Dephosphorylation of Cdc20 is required for its loading and activation of the APC/C ubiquitin ligase.
A role for the fizzy/cdc20 family of proteins in activation of the APC (显示 APC 抗体)/C distinct from substrate recruitment is reported.
Cdc20 hypomorphism causes chromatin bridging and chromosome misalignment, revealing a requirement for Cdc20 in efficient sister chromosome separation and chromosome-microtubule attachment.
The physiologically effective threshold level of Cdc20 is high for female meiosis I.
Results indicate that Cdc20 also contributes to post-anaphase activation of the APC (显示 APC 抗体)/C.
The seven tandem WD motifs of Cdc20 they are required for speriolin binding and for localization of Cdc20 to the centrosomes and nucleus, suggesting that speriolin might regulate or stabilize the folding of Cdc20 during meiosis in spermatogenic cells
Data suggest that Mad2 (显示 MXI1 抗体) and BubR1 (显示 BUB1B 抗体) must cooperate to inhibit Cdc20 activity.
Cdc20 is degraded through two independent degradation signals (degrons), the KEN (显示 PCNT 抗体) box and a newly described CRY (显示 CRY2 抗体) box.
Cdc20 and securin (显示 PTTG1 抗体) double mutant embryos could not maintain the metaphase arrest, suggesting a role of securin (显示 PTTG1 抗体) in preventing mitotic exit
Expression of the cdc20 gene is down-regulated by zif268 (显示 EGR1 抗体) in neuronal cells; altered expression of proteasome-regulatory genes following zif268 (显示 EGR1 抗体) induction may be a key component of long-lasting CNS plasticity.
Cdc20 is required for the anaphase onset of the first meiosis but not the second meiosis in mouse oocytes
findings suggest a novel function of HSF1 (显示 HSF1 抗体) frequently overexpressed in cancer cells, to inhibit APC (显示 APC 抗体)/C activity by interacting with Cdc20, and to result in aneuploidy development and genomic instability
porcine FZR1 (显示 FZR1 抗体) and CDC20 work on the maintenance of meiotic arrest at the first meiotic prophase and on the exit from M1
CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.
cell division cycle 20 homolog
, CDC20 cell division cycle 20 homolog
, cell division cycle protein 20 homolog
, cell cycle protein p55CDC