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Activates apoptosis.. 再加上，我们可以发CIDEB 蛋白 (6)和数多这个蛋白质的别的产品。
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ICAD (显示 DFFA 抗体) cDNA was 844-bp in length, containing a 522-bp open reading frame which encoded a protein of 174 amino acids.
this study shows that C5a signaling induces apoptosis in brain vascular endothelial cells in experimental lupus through activation of CIDEB
CIDEB downregulation may contribute to HCV-induced hepatic steatosis
CIDEB can act as an anti-HCV host factor and contribute to altered triglyceride homeostasis.
Authors found CIDEB to be an essential cofactor for hepatitis C virus entry into hepatocytes.
this work highlights CIDEB's role in lipid droplet (LD) fusion, and presents a new model system to study the PGC-1alpha (显示 PPARGC1A 抗体)/CIDEB pathway's role in LD dynamics and the VLDL pathway.
CIDE proteins expression correlate with tumor and survival characteristics in patients with renal cell carcinoma (显示 MOK 抗体).
PGC-1alpha (显示 PPARGC1A 抗体) plays an important role in partitioning cytoplasmic TG toward the VLDL secretory compartments and promoting VLDL secretion via transcriptional induction of CideB.
A novel mechanism for the cell-specific transcription of the human CIDE-B gene, which involves epigenetic and genetic control at separate respective promoters is reported.
Data (including data from studies in knockout mice) suggest Cideb promotes lipid storage as droplets in hepatocytes under normal diet conditions; Cidea (显示 CIDEA 抗体)/Cidec (显示 CIDEC 抗体) promote fusion of lipid droplets leading to liver steatosis in fasting (16h) and obese mice.
Cideb and perilipin 2 (显示 PLIN2 抗体) play opposing roles in controlling VLDL lipidation and hepatic lipid homeostasis
SREBP-1c (显示 SREBF1 抗体) mediates the effect of insulin (显示 INS 抗体) on the expression of Cidea (显示 CIDEA 抗体) in mouse hepatocytes.
Data suggest that Cideb is a novel regulator in controlling cholesterol homeostasis in the liver.
Cideb is a novel important regulator in lipid metabolism in the liver and may thus represent a new therapeutic target for the treatment of obesity, diabetes, and liver steatosis
Cideb protein promotes the formation of triacylglycerol-enriched VLDL particles and provides a molecular insight into VLDL lipidation and maturation in hepatocytes.
We therefore speculate that CIDEb may play a contrary role to the other CIDEs. The basic molecular information we provide here will be useful for further investigations of the physiological function of the gene, which will be helpful in better understanding the role of the CIDE family in lipid metabolism in pig models.
cell death-inducing DFFA-like effector b
, cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
, cell death activator CIDE-B
, cell death activator cide-b
, Cell death activator CIDE-B (Cell death-inducing DFFA-like effector B)
, DFFA-like B
, cell death-inducing DFFA-like effector B