anti-Cell Death-Inducing DFFA-Like Effector A (CIDEA) 抗体

CIDEA encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. 再加上,我们可以发CIDEA 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CIDEA 1149 O60543
CIDEA 12683 O70302
CIDEA 291541  
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antibodies-online.cn销售最多的anti-CIDEA 抗体

Showing 10 out of 98 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB CIDEA Antibody (C-term) (ABIN657978) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the CIDEA antibody detected the CIDEA protein (arrow). 400 μL Log in to see 10至11个工作日
$324.50
详细
小鼠 非结合性 IHC (p), WB 0.1 mg Log in to see 3至4个工作日
$302.82
详细
非结合性 ELISA, ICC, IF, IHC, IHC (p), WB Western Blot: CIDEA Antibody [NBP1-76950] - Mouse heart tissue lysate with CIDE-A antibody at 1:500 dilution. Immunohistochemistry-Paraffin: CIDEA Antibody [NBP1-76950] - Mouse heart tissue with CIDE-A antibody at 5 ug/ml. 0.1 mg Log in to see 7至9个工作日
$447.56
详细
小鼠 非结合性 IHC, WB 100 μg Log in to see 7至9个工作日
$537.17
详细
小鼠 非结合性 IP, ELISA, WB Immunoprecipitation of CIDEA transfected lysate using anti-CIDEA monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with CIDEA MaxPab rabbit polyclonal antibody. Western Blot analysis of CIDEA expression in transfected 293T cell line by CIDEA monoclonal antibody (M01), clone 4B9.<br><br>Lane 1: CIDEA transfected lysate(28.3 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μg Log in to see 11至12个工作日
$430.00
详细
非结合性 IHC (p), WB 50 μg Log in to see 6至8个工作日
$500.50
详细
小鼠 非结合性 IHC, ELISA, WB 0.1 mg Log in to see 2至3个工作日
$340.00
详细
非结合性 IHC (p), WB Human Testis (formalin-fixed, paraffin-embedded) stained with CIDEA antibody ABIN214587 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7至9个工作日
$451.00
详细
小鼠 非结合性 WB   100 μg Log in to see 7至9个工作日
$859.83
详细
非结合性 IF, WB Immunofluorescence analysis of A549 cell using CIDEA antibody. Blue: DAPI for nuclear staining. Immunofluorescence analysis of A549 cell using CIDEA antibody. 100 μL Log in to see 16 Days
$323.13
详细

通过反应活性、应用领域、克隆类型和共轭标记 CIDEA 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-CIDEA 抗体

  1. Human Monoclonal CIDEA Primary Antibody for IP, ELISA - ABIN514417 : Puri, Ranjit, Konda, Nicoloro, Straubhaar, Chawla, Chouinard, Lin, Burkart, Corvera, Perugini, Czech: Cidea is associated with lipid droplets and insulin sensitivity in humans. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal CIDEA Primary Antibody for ELISA, ICC - ABIN4298761 : Rohm, Schäfer, Laurent, Üstünel, Niopek, Algire, Hautzinger, Sijmonsma, Zota, Medrikova, Pellegata, Ryden, Kulyte, Dahlman, Arner, Petrovic, Cannon, Amri, Kemp, Steinberg, Janovska, Kopecky, Wolfrum et al.: An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice. ... in Nature medicine 2016 (PubMed)

更多抗CIDEA的相互作用对抗体

Human Cell Death-Inducing DFFA-Like Effector A (CIDEA) interaction partners

  1. Cidea, unexpectedly, functions molecularly as an indirect inhibitor of thermogenesis via inhibition of UCP1 (显示 UCP1 抗体) activity.

  2. These data establish a functional role for Cidea and suggest that, in humans, the association between Cidea levels in white fat and metabolic health is not only correlative but also causative.

  3. Since Cide-A protein plays a role in the development of metabolic diseases such as obesity, metabolic syndrome, type 2 diabetes and their vascular complications, CIDE -A gene and protein are potential therapeutic targets for these diseases.

  4. The lowest mean relative of the gene expression for CIDE-A was observed in the group of obese patients with aortic aneurysm and lipid disorders

  5. the association of tag-single nucleotide polymorphisms and haplotype structures of the CIDEA gene with obesity in a Han Chinese population, was investigated.

  6. CIDE proteins expression correlate with tumor and survival characteristics in patients with renal cell carcinoma (显示 MOK 抗体).

  7. Insulin (显示 INS 抗体) regulates CIDEA and CIDEC (显示 CIDEC 抗体) expression via PI3K (显示 PIK3CA 抗体), and it regulates expression of each protein via Akt1 (显示 AKT1 抗体)/2-and JNK2 (显示 MAPK9 抗体)-dependent pathways, respectively, in human adipocytes.

  8. The proportion of subjects with CIDEA) gene V115F (G/T) polymorphism with phenotypes of metabolic syndrome in a Chinese population was significantly higher based on genotype, in the order: GG

  9. CIDEA binds to liver X receptors and regulates their activity in vitro.

  10. These data indicate that the carboxy-terminal domain of Cidea directs lipid droplet targeting, lipid droplet clustering, and triglyceride accumulation, whereas the amino terminal domain is required for Cidea-mediated development of enlarged lipid droplets

Mouse (Murine) Cell Death-Inducing DFFA-Like Effector A (CIDEA) interaction partners

  1. results suggest that FSP27beta negatively regulates CideA-promoted enlargement of lipid droplet size in brown adipocytes.

  2. The authors show demonstrate an essential role of an amphipathic helix in CIDEA, which facilitates embedding in the lipid droplet phospholipid monolayer and binds phosphatidic acid (PA).

  3. Data (including data from studies in knockout mice) suggest Cideb (显示 CIDEB 抗体) promotes lipid storage as droplets in hepatocytes under normal diet conditions; Cidea/Cidec (显示 CIDEC 抗体) promote fusion of lipid droplets leading to liver steatosis in fasting (16h) and obese mice.

  4. Cidea is highly associated with adiposity and insulin (显示 INS 抗体) resistance, whereas Cidec (显示 CIDEC 抗体) is related to insulin (显示 INS 抗体) sensitivity

  5. data reveal an important role of Cidea in controlling lipid droplet fusion, lipid storage in brown and white adipose tissue, and the development of obesity

  6. maternal diet modulates the age-associated changes in Cidea expression leading to the development of fatty liver

  7. Cidea is a crucial regulator of sebaceous gland lipid storage and sebum lipid secretion in mice.

  8. acts as transcriptional coactivator of C/EBPbeta (显示 CEBPB 抗体) in mammary glands to control lipid secretion

  9. Cidea is a critical regulator of free fatty acid-induced apoptosis as a novel downstream target for Foxo1 (显示 FOXO1 抗体) in pancreatic beta-cells

  10. These data indicate that the carboxy-terminal domain of Cidea directs lipid droplet targeting, lipid droplet clustering, and triglyceride accumulation, whereas the amino terminal domain is required for Cidea-mediated development of enlarged lipid droplets

Cow (Bovine) Cell Death-Inducing DFFA-Like Effector A (CIDEA) interaction partners

  1. These results suggest that CIDE-A and UCP1 (显示 UCP1 抗体) are regulated by insulin (显示 INS 抗体) and/or fatty acids in mammary epithelial cells and lactating mammary glands, and thereby play an important role in lipid and energy metabolism.

CIDEA 抗原简介

蛋白简介

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

Gene names and symbols associated with CIDEA

  • cell death-inducing DFFA-like effector a (CIDEA) 抗体
  • cell death-inducing DNA fragmentation factor, alpha subunit-like effector A (Cidea) 抗体
  • cell death-inducing DFFA-like effector a (Cidea) 抗体
  • cell death-inducing DFFA-like effector a (cidea) 抗体
  • cell death-inducing DFFA-like effector a L homeolog (cidea.L) 抗体
  • AW212747 抗体
  • cide-a 抗体
  • CIDEA 抗体
  • MGC89985 抗体

Protein level used designations for CIDEA

cell death activator CIDE-A , cell death-inducing DFFA-like effector A , cell death-inducing DFFA-like effector a , cell death-inducing DNA fragmentation factor, alpha subunit-like effector A

GENE ID SPECIES
1149 Homo sapiens
12683 Mus musculus
468605 Pan troglodytes
490559 Canis lupus familiaris
527051 Bos taurus
768659 Gallus gallus
291541 Rattus norvegicus
703318 Macaca mulatta
493350 Xenopus (Silurana) tropicalis
495322 Xenopus laevis
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