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Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. 再加上，我们可以发CCAR2 蛋白 (4)和数多这个蛋白质的别的产品。
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Human Polyclonal CCAR2 Primary Antibody for ELISA, WB - ABIN1533998
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
Data suggest that DBC1 (显示 DBC1 抗体) has a dual function in regulating beta-catenin (显示 CTNNB1 抗体)-PROX1 (显示 PROX1 抗体) signaling axis: as a coactivator for both beta-catenin (显示 CTNNB1 抗体) and PROX1 (显示 PROX1 抗体).
important role for CCAR2 in maintaining cell cycle progression and promoting squamous cell carcinoma (SCC (显示 CYP11A1 抗体)) tumorigenesis.
Data show that the interaction between cell cycle and apoptosis regulator 2 (CCAR2) and heat shock protein 60 (Hsp60 (显示 HSPD1 抗体)) increases in the presence of rotenone.
Results found transcriptional levels of DBC1 (显示 DBC1 抗体),a negative regulator of HDAC3 (显示 HDAC3 抗体) significantly reduced in type 2 diabetes mellitus patients.
DBC1 (显示 DBC1 抗体) protein could be a prognostic marker of shorter recurrence-free survival in hepatocellular carcinoma patients after hepatectomy and human hepatocarcinogenesis was a multistep process accompanied by a stepwise increase in high DBC1 (显示 DBC1 抗体) expression from low-grade dysplastic nodules, through high-grade dysplastic nodules, to hepatocellular carcinoma.
Results suggest that DBC1 (显示 DBC1 抗体) is integral to the maintenance of the circadian molecular clock.
loss of DBC1 (显示 DBC1 抗体) expression plays a role in tumorigenesis and tumor progression in gallbladder carcinoma.
Proteosome-mediated degradation and poly-ubiquitination of AR were increased with the knock-down of DBC1 (显示 DBC1 抗体).
The results suggest that the PP4 (显示 ANXA5 抗体)-mediated dephosphorylation of DBC1 (显示 DBC1 抗体) is necessary for efficient damage responses in cells.
These results indicate that the expression of DBC1 and BRCA1 are closely related with in the progression of ovarian carcinomas
Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.
DBIRD complex subunit KIAA1967
, deleted in breast cancer 1
, p30 DBC protein