anti-Cell Adhesion Molecule L1-Like (CHL1) 抗体

The protein encoded by CHL1 is a member of the L1 gene family of neural cell adhesion molecules.

列出全部抗体 基因 基因ID UniProt
CHL1 10752 O00533

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非结合性 IHC, IHC (p) Immunohistochemistry: CHL-1/L1CAM-2 Antibody [NBP1-86660] - Immunohistochemical staining of human prostate shows strong positivity in peripheral nerves. 0.1 mL Log in to see 28至35个工作日
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Alexa Fluor 594 IF (p)   100 μL Log in to see 14至17个工作日
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通过反应活性、应用领域、克隆类型和共轭标记 CHL1 抗体

特性 应用范围 宿主 克隆类型 标记
Human , ,


, , , , , , , , , , , , ,

更多抗CHL1的相互作用对抗体

Human Cell Adhesion Molecule L1-Like (CHL1) interaction partners

  1. Results indicate that close homolog of L1 protein (CHL1) is downregulated by hypermethylation and that this epigenetic alteration is an independent prognostic factor in breast cancer (BC).

  2. CHL1 expression patient-derived lymphoblasts correlated with clinical outcome in depressive disorder patients.

  3. our findings suggest that miR-590-5p acts as an oncogene by targeting the CHL1 gene and promotes cervical cancer proliferation

  4. There was no statistical association between polymorphisms of the CHL1 gene and idiopathic scoliosis in a Chinese population.

  5. Our data collectively indicate that miR (显示 MLXIP 抗体)-182 in PTC (显示 F9 抗体) promotes cell proliferation and invasion through direct suppression of CHL1 (显示 DDX11 抗体), supporting the potential utility of miR (显示 MLXIP 抗体)-182 inhibition as a novel therapeutic strategy against PTC (显示 F9 抗体).

  6. The rs2272522 polymorphism (in the CHL1 gene) was found to exhibit a highly significant association with schizophrenia in the Qatari population.

  7. In 1 of 113 Colombian children with refractory epilepsy, MLPA showed a subtelomeric duplication of exon 3 of CHL1, also present in 2 relatives.

  8. CHL1 has a role in human breast tumorigenesis and progression

  9. The miRNA miR (显示 MLXIP 抗体)-151-3p had 6.7-fold higher basal expression in paroxetine-sensitive LCLs. This corresponds with lower expression of CHL1 (显示 DDX11 抗体), a target of miR (显示 MLXIP 抗体)-151-3p

  10. BACE1(-/-) axon guidance defects are likely the result of abrogated BACE1 processing of CHL1 and BACE1 deficiency produces a CHL1 loss-of-function phenotype

CHL1 抗原简介

蛋白简介

The protein encoded by this gene is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways. The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome. This protein may also play a role in the growth of certain cancers. Alternate splicing results in both coding and non-coding variants.

Gene names and symbols associated with CHL1

  • cell adhesion molecule L1-like (CHL1) 抗体
  • CALL 抗体
  • L1CAM2 抗体

Protein level used designations for CHL1

L1 cell adhesion molecule 2 , cell adhesion molecule with homology to L1CAM (close homolog of L1) , cell adhesion molecule with homology to L1CAM (close homologue of L1) , close homolog of L1 , neural cell adhesion molecule L1-like protein

GENE ID SPECIES
10752 Homo sapiens
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