anti-Cdk5 and Abl Enzyme Substrate 1 (CABLES1) 抗体

CABLES1 encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. 再加上,我们可以发Cdk5 and Abl Enzyme Substrate 1 蛋白 (4)Cdk5 and Abl Enzyme Substrate 1 试剂盒 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CABLES1 91768 Q8TDN4
CABLES1 63955 Q9ESJ1
CABLES1 307585  

antibodies-online.cn销售最多的anti-Cdk5 and Abl Enzyme Substrate 1 抗体

Showing 10 out of 26 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 ELISA, WB Western blot analysis of extracts from LOVO cells, using Ik3-1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
Cow 非结合性 WB WB Suggested Anti-CABLES1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 IF, IHC (p), WB 0.1 mg Log in to see 29至35个工作日
¥3,884.46
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Cow 非结合性 WB 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 IC, IF, IHC, WB Immunofluorescent analysis of CABLES1 staining in SHSY5Y cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of CABLES1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 7至8个工作日
¥3,941.44
详细
非结合性 ELISA, IF, IHC, WB 100 μL Log in to see 34至38个工作日
¥4,371.67
详细
非结合性 WB Western blot analysis of extract of various cells, using CABLES1 antibody. 100 μL Log in to see 34至38个工作日
¥2,882.69
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非结合性 ICC, IF, IHC (p), IHC, WB Western Blot: CABLES1 Antibody [ABIN4083003] - Western blot (WB) analysis of CABLES1 (K588) antibody in extracts from LOVO cells. 0.1 mL Log in to see 25至31个工作日
¥3,655.56
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非结合性 ELISA, WB 100 μL Log in to see 29至35个工作日
¥4,852.60
详细
非结合性 ICC, IF, WB Western Blot: CABLES1 Antibody  - Western blot analysis in human cell line RT-4 and human cell line U-251 MG. Immunocytochemistry/Immunofluorescence: CABLES1 Antibody  - Staining of human cell line U-2 OS shows localization to nuclear speckles. 100 μL Log in to see 28至35个工作日
¥3,591.24
详细

通过反应活性、应用领域、克隆类型和共轭标记 CABLES1 抗体

特性 应用范围 宿主 克隆类型
Human ,
,

Mouse (Murine) ,


Rat (Rattus) ,


引用最多的anti-Cdk5 and Abl Enzyme Substrate 1 抗体

  1. Human Polyclonal CABLES1 Primary Antibody for ELISA, WB - ABIN1534279 : Nusbaum, Zody, Borowsky, Kamal, Kodira, Taylor, Whittaker, Chang, Cuomo, Dewar, FitzGerald, Yang, Abouelleil, Allen, Anderson, Bloom, Bugalter, Butler, Cook, DeCaprio, Engels, Garber, Gnirke, Hafez et al.: DNA sequence and analysis of human chromosome 18. ... in Nature 2005 (PubMed)

更多抗Cdk5 and Abl Enzyme Substrate 1的相互作用对抗体

Zebrafish Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. cables1 is important for neural differentiation during embryogenesis, in a mechanism that likely involves interactions with the Cdk5 (显示 CDK5 抗体)/p35 (显示 CDK5R1 抗体) kinase pathway.

Human Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. Cables1/p21 (显示 CDKN1A 抗体) pathway has a strong effect on the induction of cell senescence and inhibition of cell growth, and acts as a novel regulatory mechanism in which p21 (显示 CDKN1A 抗体) is probably one of several downstream effector molecules to mediate Cables1.

  2. CABLES1 is a critical regulator of corticotrope proliferation that defines a pathway often inactivated in Cushing disease

  3. the results suggest Cables1 as a novel p21 (显示 CDKN1A 抗体) regulator through maintaining p21 (显示 CDKN1A 抗体) stability and support the model that the tumor-suppressive function of Cables1 occurs at least in part through enhancing the tumor-suppressive activity of p21 (显示 CDKN1A 抗体).

  4. Results illuminated a dynamic regulatory system through which activated Akt (显示 AKT1 抗体) and 14-3-3 (显示 YWHAQ 抗体) work directly together to neutralize a potent tumor suppressor function of Cables1.

  5. The results did not detect a significant association. It indicated that common genetic variations in CDK5 (显示 CDK5 抗体) genes might not play a role in the genetic predisposition to autism.

  6. Analysis of the RT-PCR prducts of the CABLES1 gene showed eight intragenic deletions in its mRNA transcripts; 5/8 are the result of RNA splicing.

  7. Mechanisms of CABLES1 gene inactivation in ovarian cancer development are reported.

Mouse (Murine) Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. Loss of Cables1 enhances tumor progression in the Apc (显示 APC 抗体)(Min/+) mouse model and activates the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling pathway. Cables1 is a tumor suppressor gene on chromosome 18q in this in vivo mouse model.

  2. Agenesis of the corpus callosum frequency in Cables1(+/TAS (显示 MAP3K4 抗体)) mice was significantly lower than that in Cables1(-/TAS (显示 MAP3K4 抗体)) mice, indicating that wild-type Cables1 interfered with the dominant negative effect of Cables1(TAS (显示 MAP3K4 抗体)).

  3. Data show that oocytes lacking Cables1 exhibit lower basal levels of TAp63alpha and reduced accumulation of phosphorylated TAp63alpha in response to genotoxic stress.

  4. Cables1 null mice exhibit a significant expansion of oocyte numbers at the expense of oocyte quality throughout adulthood.

Cdk5 and Abl Enzyme Substrate 1 (CABLES1) 抗原简介

蛋白简介

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CABLES1

  • Cdk5 and Abl enzyme substrate 1 (CABLES1) 抗体
  • Cdk5 and Abl enzyme substrate 1 (cables1) 抗体
  • Cdk5 and Abl enzyme substrate 1 (CpipJ_CPIJ019832) 抗体
  • CDK5 and Abl enzyme substrate 1 (Cables1) 抗体
  • Cdk5 and Abl enzyme substrate 1 (Cables1) 抗体
  • CABL1 抗体
  • Cables 抗体
  • CABLES1 抗体
  • HsT2563 抗体
  • ik3-1 抗体
  • si:dkey-2p18.3 抗体

Protein level used designations for CABLES1

Cdk5 and Abl enzyme substrate 1 , CDK5 and ABL1 enzyme substrate 1 , CDK5 and ABL1 enzyme substrate 1-like , interactor with CDK3 1 , cdk3-binding protein ik3-1 , interactor-1 with cdk3

GENE ID SPECIES
455335 Pan troglodytes
100059359 Equus caballus
100126070 Danio rerio
100345850 Oryctolagus cuniculus
100479459 Ailuropoda melanoleuca
6054063 Culex quinquefasciatus
100562423 Anolis carolinensis
100603520 Nomascus leucogenys
91768 Homo sapiens
63955 Mus musculus
768914 Gallus gallus
100682687 Canis lupus familiaris
100526114 Sus scrofa
100138286 Bos taurus
307585 Rattus norvegicus
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