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anti-Cathepsin C (CTSC) 抗体

The protein encoded by CTSC, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. 再加上,我们可以发Cathepsin C 试剂盒 (31)Cathepsin C 蛋白 (19)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CTSC 1075 P53634
CTSC 13032 P97821
CTSC 25423 P80067

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Showing 10 out of 84 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 ELISA, WB Western blot analysis of extracts from Jurkat cells, treated with etoposide 25uM 1h, using Dipeptidyl-peptidase 1 (heavy chain,Cleaved-Arg394) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
非结合性 WB 100 μL Log in to see 24至29个工作日
¥3,074.65
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非结合性 WB 100 μL Log in to see 24至29个工作日
¥3,074.65
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非结合性 ELISA, WB 100 μL Log in to see 34至38个工作日
¥4,371.67
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Cow 非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
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Cow Biotin DB, EIA, ID, IF, IP, RIA, WB   1 mL Log in to see 29至35个工作日
¥3,884.46
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山羊 非结合性 IHC (p), ELISA Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 29至35个工作日
¥4,324.07
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非结合性 ELISA, WB 100 μL Log in to see 29至35个工作日
¥4,852.60
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非结合性 WB Western blot analysis of extracts of various cells, using CTSC antibody. Immunohistochemistry of paraffin-embedded human stomach using CTSC antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 34至38个工作日
¥2,882.69
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小鼠 非结合性 IHC (p), ELISA, WB Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 29至35个工作日
¥5,950.75
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通过反应活性、应用领域、克隆类型和共轭标记 CTSC 抗体

特性 应用范围 宿主 克隆类型 标记
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更多抗Cathepsin C的相互作用对抗体

Human Cathepsin C (CTSC) interaction partners

  1. analysis of fluorescent substrates provides a detailed S' specificity study of cathepsin C

  2. Mutation screening of the CTSC gene from the two patients revealed the presence of the same homozygous nonsense mutation in Papillon-Lefevre syndrome and Haim-Munk syndromes. Phenotypic variants of the same rare disease caused by mutations of the cathepsin C (CTSC) gene.

  3. Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.

  4. CTSC was associated with albuminuria in type 2 diabetes patients.

  5. Homozygous mutation 901G>A in exon 7 of CTSC gene is associated with Papillon-Lefevre syndrome.

  6. Results identify a missense mutation in CTSC gene that segregate within a family with Papillon-Lefevre syndrome.

  7. Papillon-Lefevre syndrome cause by homozygous nonsense mutation of cathepsin C gene.

  8. CatC has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.

  9. cathepsin C in GCF (显示 GUCY2F 抗体) does not seem to have an effect on the pathogenesis of periodontal diseases.

  10. The present account of the 148.621 kb homozygous deletion on chromosome 11 is the first report of a mutational mechanism encompassing the whole CTSC gene.

Mouse (Murine) Cathepsin C (CTSC) interaction partners

  1. During the active remyelinating phase, both CysF knockdown (CysFKD) and microglial-selective CatC overexpression (CatCOE) showed a worsening of the demyelination in Plp (显示 C3 抗体)(4e/-) transgenic mice. Conversely, during the chronic demyelinating phase, CatC knockdown (CatCKD) ameliorated the demyelination. Our results suggest that the balance between CatC and CysF expression controls the demyelination and remyelination process.

  2. Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.

  3. Double immunofluorescence analysis showed that CTLA-2alpha was co-localized with cathepsin L (显示 CTSL1 抗体), cathepsin C, and TINAGL1 (显示 TINAGL1 抗体) in placenta.

  4. CatC has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.

  5. Data indicate that all-trans retinoic acid (ATRA), which induces miR (显示 MLXIP 抗体)-23a expression, decreases cathepsin C (CTSC) expression and granzyme B (显示 Gzmb 抗体) activity leading to impaired NK cell cytotoxicity.

  6. These results establish that DPPI is a major determinant of survival following Klebsiella pneumoniae lung infection and suggest that the survival disadvantage in DPPI(+/+) mice is in part due to processing of surfactant protein D (显示 SFTPD 抗体) by DPPI.

  7. found no significant role for CtsC during mammary carcinogenesis but revealed squamous carcinogenesis to be functionally dependent on CtsC

  8. Late stage cathepsin C, CXCL13 (显示 CXCL13 抗体) and Ki-67 (显示 MKI67 抗体) overexpression correlate with regional neuropathology in a bovine spongiform encephalopathy transgenic murine model.

  9. Proinflammatory cytokines induce expression and release of cathepsin C in microglial cells during neuroinflammatory progression.

  10. The production of IL-1beta (显示 IL1B 抗体) by macrophages, neutrophils, and mast cells in vitro is dependent on caspase-1 (显示 CASP1 抗体) but not on cathepsin C.

Cathepsin C (CTSC) 抗原简介

蛋白简介

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Cathepsin C (CTSC) 抗体

  • cathepsin C (ctsc) 抗体
  • cathepsin C (CTSC) 抗体
  • cathepsin C (TP03_0357) 抗体
  • cathepsin C (CMU_003360) 抗体
  • cathepsin C (TGME49_089620) 抗体
  • cathepsin C (NAEGRDRAFT_80477) 抗体
  • cathepsin C (NAEGRDRAFT_37577) 抗体
  • cathepsin C (Ctsc) 抗体
  • cathepsin C (LOC100101594) 抗体
  • cathepsin C (Smp_183330) 抗体
  • cathepsin J (Ctsj) 抗体
  • AI047818 抗体
  • CATC 抗体
  • CATP 抗体
  • CatRLP 抗体
  • CPPI 抗体
  • Ctsp 抗体
  • DPP-I 抗体
  • DPP1 抗体
  • DPPI 抗体
  • HMS 抗体
  • JP 抗体
  • JPD 抗体
  • MGC69126 抗体
  • MGC107782 抗体
  • PALS 抗体
  • PDON1 抗体
  • PLS 抗体

Protein level used designations for anti-Cathepsin C (CTSC) 抗体

cathepsin C , dipeptidyl peptidase 1 , dipeptidyl peptidase 1 isoform a preproprotein , DPPI , DPP-I , cathepsin J , Dipeptidyl-peptidase 1 , dipeptidyl peptidase I , dipeptidyl transferase , dipeptidyl-peptidase I , dipeptidyl-peptidase 1 , dipeptidylpeptidase 1 , Cat P , cathepsin L-related protein , cathepsin P , catlrp-p , gene/Cathepsin L-related protein

GENE ID SPECIES
380203 Xenopus laevis
407938 Xenopus (Silurana) tropicalis
451469 Pan troglodytes
705320 Macaca mulatta
3500364 Theileria parva strain Muguga
6997925 Cryptosporidium muris RN66
7899372 Toxoplasma gondii ME49
8851692 Naegleria gruberi strain NEG-M
8855504 Naegleria gruberi strain NEG-M
100172530 Pongo abelii
352958 Bos taurus
1075 Homo sapiens
13032 Mus musculus
25423 Rattus norvegicus
100101594 Oryctolagus cuniculus
100714387 Cavia porcellus
403458 Canis lupus familiaris
419014 Gallus gallus
101112686 Ovis aries
8346758 Schistosoma mansoni
26898 Mus musculus
29174 Rattus norvegicus
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