anti-Calsequestrin 1 (CASQ1) 抗体

The protein encoded by CASQ1 is a mitochondrial calcium-binding protein located in the luminal space of the terminal cisternae of the sarcoplasmic reticulum. 再加上,我们可以发Calsequestrin 蛋白 (13)Calsequestrin 试剂盒 (11)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CASQ1 12372 O09165
CASQ1 844 P31415
CASQ1 686019 P19633

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Showing 10 out of 27 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 5至7个工作日
¥20,898.73
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小鼠 小鼠 非结合性 IF, WB Western blot analysis of Calsequestrin on a rat muscle lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-Calsequestrin antibody. 50 μg Log in to see 24至30个工作日
¥1,258.37
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小鸡 小鼠 非结合性 ICC, IF, IHC (p), IP, IHC, WB Figure 1 shows a Western blot of calsequestrin in canine skeletal muscle extract using ABIN266947. Immunohistochemistry-Paraffin: Calsequestrin 1 Antibody (VIIID12) [ABIN266947] - Both normal and cancer biopsies of deparaffinized Human skeletal muscle tissues. 0.1 mL Log in to see 25至31个工作日
¥3,333.96
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非结合性 ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: Calsequestrin 1 Antibody [ABIN267179] - Analysis showing positive staining in the cytoplasm of Human heart tissue (right) compared with a negative control in the absence of primary antibody (left). Immunohistochemistry-Paraffin: Calsequestrin 1 Antibody [ABIN267179] - Analysis showing positive staining in the cytoplasm of Human skeletal muscle (right) compared with a negative control in the absence of primary antibody (left). 0.1 mL Log in to see 25至31个工作日
¥3,333.96
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非结合性 IHC, IHC (p), WB Western Blot: Calsequestrin 1 Antibody [NBP1-88181] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY420059) Immunohistochemistry-Paraffin: Calsequestrin 1 Antibody [NBP1-88181] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
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非结合性 WB 100 μL Log in to see 29至35个工作日
¥5,127.12
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非结合性 WB Western Blot: Calsequestrin 1 Antibody [NBP2-15682] - Sample (50 ug of whole cell lysate) A: Mouse Heart, 10% SDS PAGE gel, diluted at 1:1000. Western Blot: Calsequestrin 1 Antibody [NBP2-15682] - Sample (30 ug of whole cell lysate) A: HepG2 10% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 26至33个工作日
¥3,655.56
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小鼠 非结合性 IHC, ELISA, WB 0.05 mg Log in to see 24至29个工作日
¥5,933.60
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非结合性 IF (p), IHC (p), WB   100 μL Log in to see 5至7个工作日
¥2,610.23
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小鼠 非结合性 WB   100 μL Log in to see 29至35个工作日
¥7,803.92
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通过反应活性、应用领域、克隆类型和共轭标记 CASQ1 抗体

特性 应用范围 宿主 克隆类型
Mouse (Murine) ,
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Human , ,
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Rat (Rattus) ,
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引用最多的anti-Calsequestrin 抗体

  1. Chicken Monoclonal Calsequestrin Primary Antibody for ICC, IF - ABIN266947 : Leatherbury, Yu, Chatterjee, Walker, Yu, Tian, Lo: A novel mouse model of X-linked cardiac hypertrophy. in American journal of physiology. Heart and circulatory physiology 2008 (PubMed)
    Show all 8 Pubmed References

  2. Mouse (Murine) Monoclonal Calsequestrin Primary Antibody for IF, WB - ABIN968625 : Kobayashi, Alseikhan, Jones: Localization and characterization of the calsequestrin-binding domain of triadin 1. Evidence for a charged beta-strand in mediating the protein-protein interaction. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 Pubmed References

  3. Dog (Canine) Polyclonal Calsequestrin Primary Antibody for ICC, IF - ABIN267179 : Shankar, Messenberg, Chan, Underhill, Foster, Nabi: Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells. in Cancer research 2010 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal Calsequestrin Primary Antibody for IHC, IHC (p) - ABIN4287523 : Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model. in Proteome science 2011 (PubMed)

更多抗Calsequestrin的相互作用对抗体

Mouse (Murine) Calsequestrin 1 (CASQ1) interaction partners

  1. Calcium entry activated by ablation of both JP45 (显示 JSRP1 抗体)-CASQ1 and JP45 (显示 JSRP1 抗体)-CASQ2 (显示 CASQ2 抗体) complexes supports tetanic force development in slow twitch soleus muscles.

  2. Transient knockdown of annexin A6 (显示 ANXA6 抗体) and calsequestrin 1 protein of high-active mice with vivo-morpholinos resulted in decreased physical activity levels (P = 0.001).

  3. Ca(2 (显示 CA2 抗体)+) transients evoked by tetanic stimulation are the result of massive Ca(2 (显示 CA2 抗体)+) influx due to enhanced Ca(v)1.1 (显示 CACNA1S 抗体) channel activity, which restores muscle strength in JP45 (显示 JSRP1 抗体)/CASQ1 double knockout mice.

  4. Protein levels of CSQ1, SERCA1 (显示 ATP2A1 抗体), and SERCA2 (显示 ATP2A2 抗体) are re-adjusted in skeletal muscles depending on the demands of diverse exercise training programs.

  5. results support the view that in skeletal muscles, CASQ1 plays a key role in both Ca(2 (显示 CA2 抗体)+) homeostasis and terminal cisternae structure

  6. The results presented in this paper unmask a differential effect of CASQ1&2 ablation in fast versus slow fibers

  7. Calsequestrin not only stores Ca(2 (显示 CA2 抗体)+), but also varies its affinity in ways that progressively increase the ability of the store to deliver Ca(2 (显示 CA2 抗体)+) as it becomes depleted, a novel feedback mechanism of potentially valuable functional implications.

  8. effect of nockdown of CSQ1 in adult mouse skeletal muscle on Store-operated Ca(2 (显示 CA2 抗体)+) entry

  9. knocking down CSQ2, but not CSQ1, leads to reduced Ca2 (显示 CA2 抗体)+ storage and release in C2C12 myotubes

  10. CSQ1 is essential for the normal development of the sarcoplasmic reticulum (SR) and its calcium release units and for the storage and release of appropriate amounts of SR Ca(2 (显示 CA2 抗体)+).

Rabbit Calsequestrin 1 (CASQ1) interaction partners

  1. a mechanism for the observed in vitro and in vivo dynamic high-capacity and low-affinity Ca(2 (显示 CA2 抗体)+)-binding activity of calsequestrin

  2. Purified skeletal ryanodine receptors are similarly activated by purified triadin (显示 TRDN 抗体) or purified junctin (显示 ASPH 抗体) added to their luminal side, although a lack of competition indicated that the proteins act at independent sites.

Human Calsequestrin 1 (CASQ1) interaction partners

  1. the p.D244G variant in CASQ1 is associated with a skeletal muscle disease and alters sarcoplasmic calcium release

  2. Calsequestrin-1 monomers suppress Store-Operated Ca2 (显示 CA2 抗体)+ Entry by interacting with STIM1 (显示 STIM1 抗体) and attenuating STIM1 (显示 STIM1 抗体) aggregation via its C-terminal amino acid 362-396.

  3. the protein aggregate myopathy with benign evolution and muscle inclusions composed of excess CASQ1 due to the D244G heterozygous missense mutation in the CASQ1 gene

  4. Equilibrium dialysis and turbidity measurements showed that D244G and, to a lesser extent, M87T partially lose Ca(2 (显示 CA2 抗体)+) binding exhibited by wild type calsequestrin 1 at high Ca(2 (显示 CA2 抗体)+) concentrations.

  5. Missense mutation in CASQ1 gene causes the formation of abnormal sarcoplasmic reticulum (SR) vacuoles containing aggregates of CASQ1 results in altered Ca2 (显示 CA2 抗体)+ release, and vacuolar myopathy patients phenotype.

  6. The sarcoplasmic reticulum calcium content in human type II fibres is primarily determined by the CSQ1 abundance, and in type I fibres, by the combined amounts of both CSQ1 and CSQ2.

  7. a direct interaction of dysferlin (显示 DYSF 抗体) with Trim72/MG53 (显示 TRIM72 抗体), AHNAK (显示 AHNAK 抗体), cytoplasmic dynein (显示 DYNC1H1 抗体), myomesin-2 (显示 MYOM2 抗体) and calsequestrin-1, but not with caveolin-3 (显示 CAV3 抗体) or dystrophin (显示 DMD 抗体), is reported.

  8. CASQ1 is not a major malignant hyperthermia susceptibility locus in the North American population

  9. Downregulation of CSQ-1 in diabetic platelets and impairment of CSQ-1 in normal cells leads to disturbed Ca(2 (显示 CA2 抗体)+) release, demonstrating a potential role for CSQ-1 in the regulation of the platelet Ca(2 (显示 CA2 抗体)+) release process

  10. a mechanism for the observed in vitro and in vivo dynamic high-capacity and low-affinity Ca(2 (显示 CA2 抗体)+)-binding activity of calsequestrin

Calsequestrin (CASQ1) 抗原简介

蛋白简介

The protein encoded by this gene is a mitochondrial calcium-binding protein located in the luminal space of the terminal cisternae of the sarcoplasmic reticulum. The protein binds and putatively stores calcium ions. The protein is absent in patients with Duchenne and Becker types of muscular dystrophy.

Gene names and symbols associated with anti-Calsequestrin 1 (CASQ1) 抗体

  • calsequestrin 1 (fast-twitch, skeletal muscle) (CASQ1) 抗体
  • calsequestrin 1b (casq1b) 抗体
  • Calsequestrin-1 (casq1) 抗体
  • calsequestrin 1 (Casq1) 抗体
  • calsequestrin 1 (fast-twitch, skeletal muscle) (Casq1) 抗体
  • calsequestrin 2 (cardiac muscle) (CASQ2) 抗体
  • CASQ 抗体
  • CASQ1 抗体
  • CSQ 抗体
  • CSQ-1 抗体
  • CSQ1 抗体
  • PDIB1 抗体
  • sCSQ 抗体
  • zgc:154027 抗体

Protein level used designations for anti-Calsequestrin 1 (CASQ1) 抗体

calsequestrin-1 , Calsequestrin-1 , calsequestrin, skeletal muscle isoform , aspartactin , laminin-binding protein , skeletal muscle calsequestrin 1 , calmitin , calmitine , Aspartactin , Laminin-binding protein , calsquestrin 1 , calsequestrin homologue , calsequestrin-2

GENE ID SPECIES
508394 Bos taurus
767757 Danio rerio
100195131 Salmo salar
12372 Mus musculus
100009095 Oryctolagus cuniculus
844 Homo sapiens
101118652 Ovis aries
686019 Rattus norvegicus
100156448 Sus scrofa
395198 Gallus gallus
608401 Canis lupus familiaris
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