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Activates p53/TP53 by CDKN2A-dependent and CDKN2A- independent pathways (By similarity).. 再加上，我们可以发CDKN2A Interacting Protein 抗体 (61) 和 CDKN2A Interacting Protein 蛋白 (7)和数多这个蛋白质的别的产品。
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CARF promotes carcinogenesis in p53 (显示 TP53 ELISA试剂盒)-deficient cells by repressing p21WAF1 and promoting cell cycle progression.
The results suggest that CARF regulates early steps of pre-rRNA processing during ribosome biogenesis by controlling spatial distribution of XRN2 (显示 XRN2 ELISA试剂盒) between the nucleoplasm and nucleolus.
CARF regulates proliferative fate of human cells by dose-dependent regulation of DNA damage signaling.
Analysis of indel variations in the human disease-associated genes CDKN2AIP, WDR66, USP20 (显示 USP20 ELISA试剂盒) and OR7C2 (显示 OR7C2 ELISA试剂盒) in a Korean population.
CARF knockdown elicited DNA damage response as evidenced by increased levels of phosphorylated ATM (显示 ATM ELISA试剂盒) and gammaH2AX (显示 H2AFX ELISA试剂盒), leading to induction of mitotic arrest and eventual apoptosis.
CARF may act as a novel key regulator of the p53 (显示 TP53 ELISA试剂盒) pathway at multiple checkpoints
cooperates with human p14ARF in activating p53 (显示 TP53 ELISA试剂盒)
CARF may exert a vital control on p53 (显示 TP53 ELISA试剂盒)-HDM2-p21(WAF1 (显示 CDKN1A ELISA试剂盒)) pathway that is central to the cell cycle control, senescence, and DNA damage response of human cells
CARF exerts a vital control on the p53 (显示 TP53 ELISA试剂盒)-HDM2-p21WAF1 pathway that is frequently altered in cancer cells.
CARF plays a dual role in regulating p53 (显示 TP53 ELISA试剂盒)-mediated senescence and apoptosis, the two major tumor suppressor mechanisms.
Activates p53/TP53 by CDKN2A-dependent and CDKN2A- independent pathways (By similarity).
, collaborates/cooperates with ARF (alternate reading frame) protein
, collaborator of ARF
, CDKN2A interacting protein
, protein CDKN2AIP homolog A