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CD22 抗体

(CD22 Molecule (CD22))
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins\; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
CD22 抗体  (AA 621-725) CD22 抗体  (AA 621-725) CD22 抗体 (AA 621-725) (ABIN1724888)

CD22 适用: 人 FACS, WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 2H1C4 unconjugated

CD22 抗体  (AA 52-178) CD22 抗体  (AA 52-178) CD22 抗体 (AA 52-178) (ABIN6941120)

CD22 适用: 人 FACS, WB, ELISA, IHC, IF, Coat, StM 宿主: 小鼠 Monoclonal BLCAM-1795 unconjugated

CD22 抗体  (AA 621-725) CD22 抗体  (AA 621-725) CD22 抗体 (AA 621-725) (ABIN1724887)

CD22 适用: 人 FACS, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 1A3A11 unconjugated

CD22 抗体 by Grade

Find CD22 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CD22 抗体 by 适用

Find CD22 抗体 for a variety of species such as anti-Human CD22, anti-Mouse CD22, anti-Rat CD22. The species listed below are among those available. Click on a link to go to the corresponding products.

CD22 抗体 by 应用范围

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CD22 抗体 by 抗原表位

Find CD22 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

CD22 抗体 by 克隆形成能力

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CD22 抗体 by 克隆

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CD22 抗体 by 标记

Find CD22 抗体 with a specific conjugate such as PE, Biotin, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular CD22 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, WB, ELISA, IHC, ICC
Validations
  • (2)
  • (8)
Cat. No. ABIN1724888
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application FACS, WB, ELISA, IHC, IF, Coat, StM
Validations
  • (8)
Cat. No. ABIN6941120
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application FACS, WB, ELISA, ICC
Validations
  • (2)
  • (5)
Cat. No. ABIN1724887
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application FACS, WB, ELISA, IHC, IF, Coat
Validations
  • (5)
Cat. No. ABIN6941121
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Non-Human Primate
Application FACS, WB, IP
Validations
  • (3)
Cat. No. ABIN94034
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1497211
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Non-Human Primate
Application FACS
Validations
  • (3)
Cat. No. ABIN94037
Quantity 100 tests
Datasheet Datasheet
Reactivity Human
Application FACS
Validations
  • (3)
Cat. No. ABIN192422
Quantity 100 tests
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
  • (3)
Cat. No. ABIN7477403
Quantity 1 mL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN6138143
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, WB, IHC (p)
Validations
  • (2)
  • (3)
Cat. No. ABIN3043390
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application FACS
Validations
  • (2)
Cat. No. ABIN5067839
Quantity 100 tests
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7236519
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application FACS, WB, ELISA, IF, IP
Validations
  • (2)
Cat. No. ABIN6961048
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application FACS, IM
Validations
  • (2)
Cat. No. ABIN6941118
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD22 抗体

Lennon, Cao, Hall, Vickers, Barker: "The red blood cell as a novel regulator of human B-cell activation." in: Immunology, Vol. 163, Issue 4, pp. 436-447, (2021) (PubMed).

Kreimann, Jang, Rong, Greite, von Vietinghoff, Schmitt, Bräsen, Schiffer, Gerstenberg, Vijayan, Dittrich-Breiholz, Wang, Karsten, Gwinner, Haller, Immenschuh, Gueler: "Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation." in: Frontiers in immunology, Vol. 11, pp. 1204, (2020) (PubMed).

Ljungars, Svensson, Carlsson, Birgersson, Tornberg, Frendéus, Ohlin, Mattsson: "Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes." in: Frontiers in pharmacology, Vol. 10, pp. 847, (2019) (PubMed).

Jelicic, Cimbro, Nawaz, Huang, Zheng, Yang, Lempicki, Pascuccio, Van Ryk, Schwing, Hiatt, Okwara, Wei, Roby, David, Hwang, Kehrl, Arthos, Cicala, Fauci: "The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression." in: Nature immunology, Vol. 14, Issue 12, pp. 1256-65, (2013) (PubMed).

Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).

Tuscano, Kato, Pearson, Xiong, Newell, Ma, Gandara, ODonnell: "CD22 antigen is broadly expressed on lung cancer cells and is a target for antibody-based therapy." in: Cancer research, Vol. 72, Issue 21, pp. 5556-65, (2012) (PubMed).

Kawasaki, Rademacher, Paulson: "CD22 regulates adaptive and innate immune responses of B cells." in: Journal of innate immunity, Vol. 3, Issue 4, pp. 411-9, (2011) (PubMed).

Yu, Li, Li, Zang, Liu: "TRAIL and DR5 promote thyroid follicular cell apoptosis in iodine excess-induced experimental autoimmune thyroiditis in NOD mice." in: Biological trace element research, Vol. 143, Issue 2, pp. 1064-76, (2011) (PubMed).

Duong, Ota, Aït-Azzouzene, Aoki-Ota, Vela, Huber, Walsh, Gavin, Nemazee: "Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 8, pp. 4143-58, (2010) (PubMed).

Walker, Smith: "CD22: an inhibitory enigma." in: Immunology, Vol. 123, Issue 3, pp. 314-25, (2008) (PubMed).

Aliases for CD22 抗体

CD22 antigen (Cd22) 抗体
CD22 molecule (CD22) 抗体
CD22 molecule (Cd22) 抗体
A530093D23 抗体
Lyb-8 抗体
Lyb8 抗体
SIGLEC-2 抗体
siglec-2 抗体
SIGLEC2 抗体
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