Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 蛋白 (BLOC1S1)

BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. 再加上,我们可以发BLOC1S1 抗体 (18)BLOC1S1 试剂盒 (13)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
BLOC1S1 2647 P78537
BLOC1S1 288785 D3ZKU7
BLOC1S1 14533 O55102
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Showing 10 out of 11 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$4,331.68
详细
大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$4,331.68
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大肠杆菌(E. Coli) GST tag Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) (AA 1-153), (full length) protein (GST tag) 50 μg Log in to see 13至16个工作日
$242.00
详细
酵母菌 Arabidopsis thaliana His tag   1 mg Log in to see 60至71个工作日
$2,337.50
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小麦胚 GST tag 2 μg Log in to see 11至12个工作日
$205.80
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$405.71
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10至12个工作日
$785.40
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酵母菌 Xenopus tropicalis His tag   1 mg Log in to see 60至71个工作日
$2,253.17
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酵母菌 Cow His tag   1 mg Log in to see 60至71个工作日
$2,253.17
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酵母菌 大鼠 His tag   1 mg Log in to see 60至71个工作日
$2,253.17
详细

BLOC1S1 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,
Rat (Rattus)

Mouse (Murine)

更多Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1)互动伙伴

Human Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) interaction partners

  1. The mitochondrial acetylation status controlled by Sirt3 (显示 SIRT3 蛋白) and its proposed opponent GCN5L1 is an important regulator of the metabolic adaptation of mitochondrial translation.

  2. Using cancer cell lines, the study shows that BLOC1S1 mRNA is specifically cleaved by IRE1 (显示 ERN1 蛋白) at guanine 444, but only under conditions of IRE1 (显示 ERN1 蛋白) hyperactivation.

  3. The Hermansky-Pudlak syndrome complex BLOC-1 and its cargo PI4KIIalpha interact with regulators of the actin cytoskeleton.

  4. BLOS1 interacts with KXD1.

  5. GCN5L1/BLOC1S1 regulates lysine acetylation in mitochondria.

  6. Quantitative proteomic studies expand the functional repertoire of the BLOC-1 complex and provide insight into putative molecular pathways of schizophrenia susceptibility.

  7. Together this study data provide evidence for the involvement of the BLOC-1 protein complex in SZ pathogenesis.

  8. Experimental investigation of five specific genes, AP3B1 (显示 AP3B1 蛋白), ATP6AP1 (显示 ATP6AP1 蛋白), BLOC1S1, LAMP2 (显示 LAMP2 蛋白), and RAB11A (显示 RAB11A 蛋白), has confirmed novel roles for these proteins in the proper initiation of macroautophagy in amino acid-starved fibroblasts.

  9. Biogenesis of Lysosome-related Organelles co (显示 SNAPIN 蛋白)mplex-1 (BLOC-1) subunit 1 (BLOS1).

Mouse (Murine) Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) interaction partners

  1. Acetylation of cardiac mitochondrial fatty acid oxidation enzymes by GCN5L1 significantly upregulates their activity in diet-induced obese mice.

  2. TDH, responsible for mitochondrial production of acetyl-CoA (显示 LPCAT1 蛋白) in mouse embryonic stem cells, and the acetyltransferase GCN5L1 cooperate to acetylate Lys501 in KBP, allowing its recognition by and degradation via Fbxo15 (显示 FBXO15 蛋白), an F-box protein (显示 FBXO30 蛋白) transcriptionally controlled by the pluripotency core factors and repressed following differentiation.

  3. BLOS1 interacts with sorting nexin 2 (显示 SNX2 蛋白) and the ESCRT-I (显示 VPS28 蛋白) component TSG101 (显示 TSG101 蛋白) to mediate the sorting of EGFR (显示 EGFR 蛋白) into endosomal compartments

  4. Here we show that genetic deletion of GCN5L1 has a direct positive effect on the expression and activity of Transcriptional Factor EB (TFEB (显示 TFEB 蛋白)), which acts as a master regulator of autophagy.

  5. Mutations in the human genes encoding Snapin (显示 SNAPIN 蛋白) and the BLOS proteins could underlie novel forms of Hermansky-Pudlak syndrome as seen in mouse models

  6. Defects in all the 5 known components of BLOC-1 (显示 PLDN 蛋白), including RP, cause severe Hermansky Pudlak syndrome in mice, suggesting that the subunits are nonredundant and that BLOC-1 (显示 PLDN 蛋白) plays a key role in organelle biogenesis.

  7. These results indicate that the BLOC-1 (显示 PLDN 蛋白) and AP-3 (显示 AP3B1 蛋白) protein complexes affect the targeting of SNARE (显示 VTI1B 蛋白) and non-SNARE (显示 VTI1B 蛋白) AP-3 (显示 AP3B1 蛋白) cargoes and suggest a function of the BLOC-1 (显示 PLDN 蛋白) complex in membrane protein sorting.

蛋白简介BLOC1S1

蛋白简介

BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004

Gene names and symbols associated with BLOC1S1

  • biogenesis of lysosomal organelles complex 1 subunit 1 (BLOC1S1)
  • biogenesis of lysosomal organelles complex-1, subunit 1 (Bloc1s1)
  • AI839753 蛋白
  • BLOS1 蛋白
  • Gcn5l1 蛋白
  • MICoA 蛋白
  • RT14 蛋白

Protein level used designations for BLOC1S1

BLOC subunit 1 , BLOC-1 subunit 1 , GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1 , GCN5 general control of amino-acid synthesis 5-like 1 , GCN5-like protein 1 , MTA1-interacting coactivator , biogenesis of lysosome-related organelles complex 1 subunit 1 , biogenesis of lysosome-related organelles complex-1, subunit 1 , GCN5 general control of amino acid synthesis-like 1 , general control of amino acid synthesis, yeast homolog-like 1 , general control of amino acid synthesis-like 1

GENE ID SPECIES
2647 Homo sapiens
615149 Bos taurus
288785 Rattus norvegicus
100190807 Pongo abelii
14533 Mus musculus
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