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The protein encoded by BAAT is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. 再加上，我们可以发Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) 蛋白 (4)和数多这个蛋白质的别的产品。
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Cow (Bovine) Polyclonal BAAT Primary Antibody for WB - ABIN2782317
Tougou, Fukuda, Ito, Yamazaki, Fujio, Azuma: Genetic polymorphism of bile acid CoA: amino acid N-acyltransferase in Japanese individuals. in Drug metabolism and pharmacokinetics 2007
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These results indicate that even small changes in the carboxy terminus of BAAT can have significant effects on activity and substrate specificity
Case Report: mmunostaining may facilitate diagnosis in bile-acid amidation defects in bile acid-CoA: amino acid N-acyltransferase deficiency.
there is an essential catalytic triad within hBAT consisting of Cys (显示 DNAJC5 抗体)-235, His-362, and Asp (显示 ASIP 抗体)-328 with Cys (显示 DNAJC5 抗体)-235 serving as the probable nucleophile and thus the site of covalent attachment of the bile acid molecule
Familial hypercholanemia in Amish individuals is associated with mutations in tight junction protein 2 (显示 TJP2 抗体) (encoded by TJP2 (显示 TJP2 抗体), also known as ZO-2 (显示 TJP2 抗体)) and bile acid Coenzyme A: amino acid N-acyltransferase (encoded by BAAT).
cytosolic BACAT enzyme may play important roles in protection against toxicity by accumulation of unconjugated bile acids and non-esterified very long-chain fatty acids
identification of 3 novel SNPs, 147C>T in exon 2 (silent), 602G>C in exon 3 (Arg201Pro) & 1134C>T in exon 4 (silent), in the BAAT gene by resequencing the entire coding region and the exon-intron junctions of 100 Japanese individuals
Data show that dose-response inactivation by 4HNE (4-hydroxynonenal) of hBAT (human bile acid CoA:amino acid N-acyltransferase) and CKBB (显示 CKB 抗体) (cytosolic brain isoform of creatine kinase) is associated with site-specific modifications.
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)
, Bile acid-CoA:amino acid N-acyltransferase
, bile acid-CoA:amino acid N-acyltransferase
, long-chain fatty-acyl-CoA hydrolase
, bile acid-Coenzyme A dehydrogenase: amino acid n-acyltransferase
, bile acid-Coenzyme A: amino acid N-acyltransferase
, glycine N-choloyltransferase
, taurine N-acyltransferase