anti-Bicaudal C Homolog 1 (Drosophila) (BICC1) 抗体

BICC1 encodes an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. 再加上,我们可以发BICC1 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
BICC1 80114 Q9H694
BICC1 83675 Q99MQ1
BICC1 361832  

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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IHC (p), WB Western blot analysis of BICC1 Antibody (N-term) (ABIN390954) in HL-60 cell line lysates (35 µg/lane). BICC1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with BICC1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 5至8个工作日
¥2,606.76
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非结合性 WB 400 μL Log in to see 5至8个工作日
¥2,606.76
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非结合性 EIA, WB   0.4 mL Log in to see 30至37个工作日
¥3,065.96
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非结合性 IHC, WB 100 μL Log in to see 24至29个工作日
¥3,240.37
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山羊 非结合性 ELISA   0.1 mg Log in to see 24至29个工作日
¥4,432.21
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Bat 山羊 非结合性 ELISA   100 μg Log in to see 29至35个工作日
¥5,127.12
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Bat 山羊 非结合性 ELISA   100 μg Log in to see 29至35个工作日
¥6,088.05
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山羊 非结合性 ELISA, WB   100 μg Log in to see 24至29个工作日
¥9,230.97
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山羊 非结合性 EIA, IP   0.1 mg Log in to see 30至37个工作日
¥3,065.96
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非结合性 ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: BICC1 Antibody [NBP1-94171] - Staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli. Immunohistochemistry: BICC1 Antibody [NBP1-94171] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules and cells in glomeruli. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
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通过反应活性、应用领域、克隆类型和共轭标记 BICC1 抗体

特性 应用范围 宿主 克隆类型 标记
Human , ,
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Mouse (Murine) ,


Rat (Rattus) , ,


引用最多的anti-BICC1 抗体

  1. Human Polyclonal BICC1 Primary Antibody for WB - ABIN1944768 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Show all 3 references for 1944768

  2. Human Polyclonal BICC1 Primary Antibody for IHC (p), WB - ABIN390954 : Grupe, Li, Rowland, Nowotny, Hinrichs, Smemo, Kauwe, Maxwell, Cherny, Doil, Tacey, van Luchene, Myers, Wavrant-De Vrièze, Kaleem, Hollingworth, Jehu, Foy, Archer, Hamilton, Holmans, Morris, Catanese et al.: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. ... in American journal of human genetics 2005 (PubMed)
    Show all 2 references for 390954

更多抗BICC1的相互作用对抗体

Zebrafish Bicaudal C Homolog 1 (Drosophila) (BICC1) interaction partners

  1. These results demonstrate that the function of Bicc1 in the kidney is evolutionarily conserved, thus supporting the use of zebrafish as an alternative in vivo model to study the role of mammalian Bicc1 in renal cyst formation.

Human Bicaudal C Homolog 1 (Drosophila) (BICC1) interaction partners

  1. Suggest allelic changes in the regulation of the BICC1 gene in amygdala neurones may contribute to mood disorders.

  2. Results provide some support for the involvement of BICC1 and PCLO (显示 PCLO 抗体) in late-life depressive disorders and preliminary evidence that these genetic variants may also influence brain structural volumes

  3. findings identify a role for increased levels of BICC1 in the pathophysiology of depressive behavior

  4. Polymorphisms in intron 2 of BICC1 are associated with its expression and bone (显示 BEST1 抗体) mineral density (BMD)

  5. The minor T-allele of BICC1 has a protective role against major depressive disorder and its known structural and functional brain changes.

  6. The nonsense mutation identified in BICC1 and associated with cystic renal dysplasia results in a complete loss of Wnt (显示 WNT2 抗体) inhibitory activity. The point mutation in the SAM (显示 TTN 抗体) domain results in a 22% loss of activity.

Mouse (Murine) Bicaudal C Homolog 1 (Drosophila) (BICC1) interaction partners

  1. Polymerization is a novel disease-relevant mechanism both to stabilize Bicc1 and to present associated mRNAs in specific silencing platforms.

  2. discovered that loss of the Pkd1 (显示 PKD1 抗体) gene product, polycystin-1 (PC1 (显示 PKD1 抗体)), whose mutation causes human autosomal dominant polycystic kidney disease (ADPKD), downregulates Bicc1 expression in vitro and in vivo

  3. Bicc1 is a novel regulator of osteoblastogenesis and bone mineral density (BMD (显示 BEST1 抗体))

  4. Bicc1 KH domains bind the 3' UTRs of AC6 (显示 ADCY6 抗体) and PKIa (显示 PKIA 抗体) mRNAs and cognate miRNA precursors, whereas the SAM (显示 TTN 抗体) domain loads a silencing complex with AGO2 (显示 EIF2C2 抗体). AC6 (显示 ADCY6 抗体) and PKIa (显示 PKIA 抗体) protein levels increase in cystic Bicc1-/- mouse kidneys.

  5. lack of Bicc1 leads to disruption of normal cell-cell junctions.

  6. Data suggest that Bicc1 functions by modulating the expression of polycystin 2 (Pkd2 (显示 PKD2 抗体) by antagonizing the repressive activity of the miR-17 microRNA family on the 3'UTR (显示 UTS2R 抗体) of Pkd2 (显示 PKD2 抗体) mRNA.

  7. Binds homoribopolymers in vitro; the third K homology domain is necessary and sufficient for in vitro Bicc1 RNA binding.

  8. Bicc1 and SamCystin (显示 ANKS6 抗体) interact at the protein level suggesting that they function in a common molecular pathway that when perturbed, is involved in cystogenesis.

  9. Data report that targeted inactivation of BicC randomizes left-right asymmetry by disrupting the planar alignment of motile cilia required for cilia-driven fluid flow, and that BicC can uncouple Dvl2 (显示 DVL2 抗体) signaling from the canonical Wnt (显示 WNT2 抗体) pathway.

BICC1 抗原简介

蛋白简介

This gene encodes an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. Mouse studies identified the corresponding protein to be under strict control during cell differentiation and to be a maternally provided gene product.

Gene names and symbols associated with BICC1

  • bicaudal C homolog 1 (Drosophila) (BICC1) 抗体
  • bicaudal C homolog 1b (Drosophila) (bicc1b) 抗体
  • bicaudal C homolog 1 (bicc1) 抗体
  • bicaudal C homolog 1 (Drosophila) (Bicc1) 抗体
  • Bic-C 抗体
  • Bicaudal-C 抗体
  • BICC 抗体
  • bicc1 抗体
  • bpk 抗体
  • CYSRD 抗体
  • jcpk 抗体
  • x-Bic-C 抗体
  • xBic-C 抗体

Protein level used designations for BICC1

bicaudal C homolog 1 (Drosophila) , bicaudal C homolog 1-like , bicaudal C homolog 1 , protein bicaudal C homolog 1-like , bic-C , protein bicaudal C homolog 1 , juvenile congenital polycystic kidney disease , polycystic kidney mutation of BALB/c origin

GENE ID SPECIES
423604 Gallus gallus
450473 Pan troglodytes
537799 Bos taurus
571411 Danio rerio
733856 Xenopus (Silurana) tropicalis
701228 Macaca mulatta
100013824 Monodelphis domestica
100072191 Equus caballus
100412529 Callithrix jacchus
100466363 Ailuropoda melanoleuca
100589900 Nomascus leucogenys
80114 Homo sapiens
608626 Canis lupus familiaris
83675 Mus musculus
361832 Rattus norvegicus
100154253 Sus scrofa
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