anti-Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) 抗体

BCAM encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. 再加上,我们可以发BCAM 试剂盒 (18)BCAM 蛋白 (14)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
BCAM 57278 Q9R069
BCAM 4059 P50895
BCAM 78958 Q9ESS6
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Showing 10 out of 99 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-BCAM Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate WB Suggested Anti-BCAM <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: HepG2 cell lysate <br /> BCAM is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-BCAM Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: HepG2 cell lysate BCAM is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells 100 μL Log in to see 2至3个工作日
$289.00
详细
小鼠 非结合性 CyTOF, ELISA (Capture), FACS, WB Detection of BCAM in Huh-7 Human Cell Line by Flow Cytometry. Huh-7 human hepatoma cell line was stained with Mouse Anti-Human BCAM Monoclonal Antibody. Detection of BCAM in Huh-7 Human Cell Line by Flow Cytometry. Huh-7 human hepatoma cell line was stained with Mouse Anti-Human BCAM Monoclonal Antibody. 500 μg Log in to see 8至9个工作日
$346.50
详细
非结合性 ELISA, WB 100 μL Log in to see 16 Days
$175.80
详细
Cow 非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
小鼠 非结合性 FACS, WB   0.2 mg Log in to see 6至8个工作日
$500.50
详细
非结合性 IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded mouse spleen labeled with Rabbit Anti CD239 Polyclonal Antibody, Unconjugated (ABIN873081) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3至7个工作日
$295.90
详细
小鼠 PE FACS Detection of BCAM in Huh-7 Human Cell Line by Flow Cytometry. Huh-7 human hepatoma cell line was stained with Mouse Anti-Human BCAM PE-conjugated Mono-clonal Antibody. 100 Tests Log in to see 8至9个工作日
$309.75
详细
小鼠 Allophycocyanin FACS Detection of BCAM in Huh-7 Human Cell Line by Flow Cytometry. Huh-7 human hepatoma cell line was stained with Mouse Anti-Human BCAM APC-conjugated Monoclonal Antibody. Detection of BCAM in Huh-7 Human Cell Line by Flow Cytometry. Huh-7 human hepatoma cell line was stained with Mouse Anti-Human BCAM APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8至9个工作日
$357.00
详细
Alexa Fluor 594 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细

通过反应活性、应用领域、克隆类型和共轭标记 BCAM 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine) ,


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引用最多的anti-BCAM 抗体

  1. Human Monoclonal BCAM Primary Antibody for IHC (fro), FACS - ABIN2479400 : Muto: Fulminant hepatitis--is the survival improving? in Gastroenterologia Japonica 1992 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal BCAM Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900214 : Kikkawa, Miwa, Tohara, Hamakubo, Nomizu: An antibody to the lutheran glycoprotein (Lu) recognizing the LU4 blood type variant inhibits cell adhesion to laminin α5. in PLoS ONE 2011 (PubMed)

更多抗BCAM的相互作用对抗体

Mouse (Murine) Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) interaction partners

  1. Lu/BCAM may have a critical role in facilitating the accumulation of monocytes and macrophages, thereby exacerbating renal injury in crescentic glomerulonephritis.

  2. Lutheran (Lu), also known as basal cell adhesion molecule (B-CAM), competes with integrins for binding to laminin alpha5, a subunit of LM-511, a major component of basement membranes.

  3. Lu/BCAM, as a laminin receptor, is involved in vivo in the maintenance of normal basement membrane organization in the kidney and intestine.

Human Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) interaction partners

  1. Cytometry analysis evidenced a specific expression profile on reticulocytes of SCA infants, with notably an increased expression of the adhesion molecules Lu/BCAM, ICAM-4 (显示 ICAM4 抗体) and LFA-3, both in percentage of positive cells and in surface density.

  2. Through molecular genotyping we also identified polymorphisms in RhCE (显示 RHCE 抗体), Kell, Duffy, Colton, Lutheran and Scianna loci in donors and patients.

  3. The variable levels of expression of mutated JAK2 (显示 JAK2 抗体) and BCAM (显示 BCAT2 抗体) proteins determine different adhesion patterns of erythrocytes from polycythemia vera (显示 IGF2BP3 抗体) patients.

  4. These studies revealed amino acids 720 to 1014 of CNF1 as the binding site for Lu/BCAM.

  5. High BCAM (显示 BCAT2 抗体) expression is associated with hepatocellular carcinoma.

  6. Adhesion of sickle reticulocytes to HC-treated endothelial cells was decreased despite the HC-derived increase of Lu/BCAM expression.

  7. tumor cell migration on LM-511 requires that Lu/B-CAM competitively modulates cell attachment through integrins.

  8. DARC (显示 DARC 抗体) and BCAM (显示 BCAT2 抗体) expression was associated with pathogenesis of thyroid carcinoma and correlated with clinical-pathological features.

  9. Glu425 in the Lu glycoprotein is required for expression of Lu7, and Ala425 is associated with the LU:-7 phenotype. This completes the molecular basis associated with all antigens known to be in the Lutheran blood group system.

  10. Increases in adhesion frequency provide significant evidence of the role of epinephrine in BCAM/Lu-laminin and ICAM-4 (显示 ICAM4 抗体)-alpha(v)beta(3) bonding, and suggest mechanisms of vaso-occlusion during physical exertion in sickle cell trait.

BCAM 抗原简介

蛋白简介

This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with BCAM

  • basal cell adhesion molecule (Lutheran blood group) (bcam) 抗体
  • basal cell adhesion molecule (Lutheran blood group) L homeolog (bcam.L) 抗体
  • basal cell adhesion molecule (Lutheran blood group) (BCAM) 抗体
  • basal cell adhesion molecule (BCAM) 抗体
  • basal cell adhesion molecule (Bcam) 抗体
  • basal cell adhesion molecule (Lutheran blood group) (Bcam) 抗体
  • 1200005K12Rik 抗体
  • AU 抗体
  • B-CAM 抗体
  • CD239 抗体
  • Gplu 抗体
  • Lu 抗体
  • MGC81012 抗体
  • MSK19 抗体
  • prr2 抗体
  • zgc:154034 抗体

Protein level used designations for BCAM

basal cell adhesion molecule (Lutheran blood group) , Auberger b antigen , Lutheran blood group , basal cell adhesion molecule (Lu and Au blood groups) , basal cell adhesion molecule , LU , basal cell adhesion molecule-like , B-CAM cell surface glycoprotein , lutheran antigen , lutheran glycoprotein , B-cell adhesion molecule , F8/G253 antigen , antigen identified by monoclonal antibody F8 , glycoprotein 95kDa , Lutheran blood group (Auberger b antigen included)

GENE ID SPECIES
100036718 Xenopus (Silurana) tropicalis
444320 Xenopus laevis
484456 Canis lupus familiaris
714568 Macaca mulatta
744276 Pan troglodytes
767689 Danio rerio
100070622 Equus caballus
100446557 Pongo abelii
100477918 Ailuropoda melanoleuca
57278 Mus musculus
4059 Homo sapiens
78958 Rattus norvegicus
282862 Bos taurus
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