BAG3 抗体
(BCL2-Associated Athanogene 3 (BAG3))
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008].
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Latest Publications for our BAG3 抗体
: "Bcl-2-associated athanogene 3(BAG3) is associated with tumor cell proliferation, migration, invasion and chemoresistance in colorectal cancer." in: BMC cancer, Vol. 18, Issue 1, pp. 793, (2019) (PubMed).: "Familial Dilated Cardiomyopathy Caused by a Novel Frameshift in the BAG3 Gene." in: PLoS ONE, Vol. 11, Issue 7, pp. e0158730, (2016) (PubMed).
: "Modulation of BAG3 Expression and Proteasomal Activity by sAPPα Does Not Require Membrane-Tethered Holo-APP." in: Molecular neurobiology, (2015) (PubMed).
: "Expression and clinical role of chemoresponse-associated genes in ovarian serous carcinoma." in: Gynecologic oncology, Vol. 139, Issue 1, pp. 30-9, (2015) (PubMed).
: "Expression of Bcl-2 and the antiapoptotic BAG family proteins in ovarian cancer." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 21, Issue 6, pp. 518-24, (2013) (PubMed).
: "Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 300, Issue 2, pp. G292-302, (2011) (PubMed).
: "Bag3 promotes resistance to apoptosis through Bcl-2 family members in non-small cell lung cancer." in: Oncology reports, Vol. 27, Issue 1, pp. 109-13, (2011) (PubMed).
: "Chaperone-assisted selective autophagy is essential for muscle maintenance." in: Current biology : CB, Vol. 20, Issue 2, pp. 143-8, (2010) (PubMed).
: "Bis deficiency results in early lethality with metabolic deterioration and involution of spleen and thymus." in: American journal of physiology. Endocrinology and metabolism, Vol. 295, Issue 6, pp. E1349-57, (2008) (PubMed).
: "The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines." in: FEBS letters, Vol. 503, Issue 2-3, pp. 151-7, (2001) (PubMed).
Aliases for BAG3 抗体
BCL2 associated athanogene 3 L homeolog (bag3.L) 抗体BCL2-associated athanogene 3 (bag3) 抗体
BCL2 associated athanogene 3 (BAG3) 抗体
BCL2 associated athanogene 3 (bag3) 抗体
BCL-2-associated athanogene 3 (BAG3) 抗体
BCL2-associated athanogene 3 (Bag3) 抗体
Bcl2-associated athanogene 3 (Bag3) 抗体
AA407278 抗体
ATBAG3 抗体
BAG-3 抗体
BAG3 抗体
bag3-A 抗体
BCL-2-associated athanogene 3 抗体
BIS 抗体
Bis 抗体
CAIR-1 抗体
MFM6 抗体
mg638 抗体
MGC53113 抗体
T28J14.160 抗体
T28J14_160 抗体
zgc:100859 抗体
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