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AGTRAP encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. 再加上，我们可以发Angiotensin II Receptor-Associated Protein 抗体 (48) 和 Angiotensin II Receptor-Associated Protein 蛋白 (4)和数多这个蛋白质的别的产品。
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A role for AT1 receptor-associated proteins in blood pressure regulation
ATRAP, a directly interacting and functionally inhibiting molecule of AT1R (显示 AGTR1 ELISA试剂盒), plays a protective role against the development of systemic insulin (显示 INS ELISA试剂盒) resistance via regulatory effects on adipose tissue function.
The phosphatidylinositol transfer protein (显示 PITPNA ELISA试剂盒) RdgBbeta (显示 PITPNC1 ELISA试剂盒) binds 14-3-3 (显示 YWHAQ ELISA试剂盒) via its unstructured C-terminus, whereas its lipid-binding domain interacts with the integral membrane protein ATRAP (angiotensin II type I receptor-associated protein).
the GG genotype of the AGTRAP rs11121816 T/G single nucleotide polymorphism was associated with increased mortality in two cohorts of patients who had septic shock.
CSF (显示 CSF2 ELISA试剂盒) angiotensin II, ACE (显示 ACE ELISA试剂盒), and ACE2 (显示 ACE2 ELISA试剂盒) levels are decreased in neuromyelitis optica/NMO spectrum disorder patients with anti-AQP4 (显示 AQP4 ELISA试剂盒) antibody, reflecting severe destruction of perivascular astrocytes
Small interfering RNA significantly attenuates angiotensin II type 1 receptor (显示 AGTR1 ELISA试剂盒)-stimulated inositol phosphate formation.
cloned a new human gene cDNA that codes for a homolog of the murine Agtrap protein
isolation of a novel protein, ARAP1 (显示 ARAP1 ELISA试剂盒), which promotes recycling of angiotensin(1A) to the plasma membrane in HEK (显示 EPHA3 ELISA试剂盒)-293 cells
CAML (显示 CAMLG ELISA试剂盒) is an important signal transducer for the actions of Ang II (显示 AGT ELISA试剂盒) in regulating the calcineurin-NFAT (显示 NFATC1 ELISA试剂盒) pathway and the interaction of CAML (显示 CAMLG ELISA试剂盒) with ATRAP may mediate the Ang II (显示 AGT ELISA试剂盒) actions in vascular physiology
Renal ATRAP downregulation is involved in the onset and progression of blood pressure elevation caused by renal mass reduction, and implicates ATRAP as a therapeutic target for hypertension in chronic kidney disease.
These results implied that AngII could effectively induce EpiCs to differentiate into vascular smooth muscle-like cells through the AT1 receptor.
ATRAP expression in brown adipose tissue does not influence the pathogenesis of dietary obesity or metabolic disorders.
Identify Atrap as a novel regulatory protein (显示 TGFB1 ELISA试剂盒) of the cardiac Ca(2+)-ATPase SERCA2a (显示 CA-P60A ELISA试剂盒). Suggest that Atrap enhances the activity of SERCA2a (显示 ATP2A2 ELISA试剂盒) and, consequently, facilitates ventricular relaxation.
These results suggest that increased formation of AT1R-P2Y6R (显示 P2RY6 ELISA试剂盒) heterodimers with age may increase the likelihood of hypertension induced by Ang II (显示 AGT ELISA试剂盒).
although erythropoiesis and blood pressure are negatively controlled through the AT1 receptor inhibition in vivo, the pathways involved are complex and distinct
Distal tubule-dominant enhancement of ATRAP inhibits pathological renal sodium reabsorption and blood pressure elevation in response to high salt loading.
AT1R knockout mice were less vulnerable to controlled cortical impact-induced injury.
The inhibition of degradation of angiotensin II type 1 receptor (显示 AGTR1 ELISA试剂盒)-associated protein (显示 BCAP31 ELISA试剂盒) (ATRAP) and inactivation of AT1R-mediated p38 MAPK (显示 MAPK14 ELISA试剂盒) and STAT3 (显示 STAT3 ELISA试剂盒) signaling pathways, are involved cardiac hypertrophy.
Activation of aortic vascular ATRAP partially inhibits the Nox4 (显示 NOX4 ELISA试剂盒)/p22(phox (显示 CYBA ELISA试剂盒))-ROS (显示 ROS1 ELISA试剂盒)-p38MAPK (显示 MAPK14 ELISA试剂盒)/JNK (显示 MAPK8 ELISA试剂盒) pathway and pathological aortic hypertrophy provoked by Ang II (显示 AGT ELISA试剂盒)-mediated hypertension.
This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.
angiotensin II receptor-associated protein
, type-1 angiotensin II receptor-associated protein
, Type-1 angiotensin II receptor-associated protein
, AT1 receptor-associated protein
, ATI receptor-associated protein
, angiotensin II, type I receptor-associated protein
, AT1 receptor
, angiotensin II receptor, type I