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AGTRAP encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. 再加上，我们可以发Angiotensin II Receptor-Associated Protein 蛋白 (4) 和 Angiotensin II Receptor-Associated Protein 试剂盒 (3)和数多这个蛋白质的别的产品。
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Human Monoclonal AGTRAP Primary Antibody for WB - ABIN395167
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
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A role for AT1 receptor-associated proteins in blood pressure regulation
ATRAP, a directly interacting and functionally inhibiting molecule of AT1R (显示 AGTR1 抗体), plays a protective role against the development of systemic insulin (显示 INS 抗体) resistance via regulatory effects on adipose tissue function.
The phosphatidylinositol transfer protein (显示 PITPNA 抗体) RdgBbeta (显示 PITPNC1 抗体) binds 14-3-3 (显示 YWHAQ 抗体) via its unstructured C-terminus, whereas its lipid-binding domain interacts with the integral membrane protein ATRAP (angiotensin II type I receptor-associated protein).
the GG genotype of the AGTRAP rs11121816 T/G single nucleotide polymorphism was associated with increased mortality in two cohorts of patients who had septic shock.
CSF (显示 CSF2 抗体) angiotensin II, ACE (显示 ACE 抗体), and ACE2 (显示 ACE2 抗体) levels are decreased in neuromyelitis optica/NMO spectrum disorder patients with anti-AQP4 (显示 AQP4 抗体) antibody, reflecting severe destruction of perivascular astrocytes
Small interfering RNA significantly attenuates angiotensin II type 1 receptor (显示 AGTR1 抗体)-stimulated inositol phosphate formation.
cloned a new human gene cDNA that codes for a homolog of the murine Agtrap protein
isolation of a novel protein, ARAP1 (显示 ARAP1 抗体), which promotes recycling of angiotensin(1A) to the plasma membrane in HEK (显示 EPHA3 抗体)-293 cells
CAML (显示 CAMLG 抗体) is an important signal transducer for the actions of Ang II (显示 AGT 抗体) in regulating the calcineurin (显示 PPP3CA 抗体)-NFAT (显示 NFATC1 抗体) pathway and the interaction of CAML (显示 CAMLG 抗体) with ATRAP may mediate the Ang II (显示 AGT 抗体) actions in vascular physiology
Identify Atrap as a novel regulatory protein (显示 TGFB1 抗体) of the cardiac Ca(2+)-ATPase SERCA2a (显示 CA-P60A 抗体). Suggest that Atrap enhances the activity of SERCA2a (显示 ATP2A2 抗体) and, consequently, facilitates ventricular relaxation.
These results suggest that increased formation of AT1R-P2Y6R (显示 P2RY6 抗体) heterodimers with age may increase the likelihood of hypertension induced by Ang II (显示 AGT 抗体).
although erythropoiesis and blood pressure are negatively controlled through the AT1 receptor inhibition in vivo, the pathways involved are complex and distinct
Distal tubule-dominant enhancement of ATRAP inhibits pathological renal sodium reabsorption and blood pressure elevation in response to high salt loading.
AT1R knockout mice were less vulnerable to controlled cortical impact-induced injury.
The inhibition of degradation of angiotensin II type 1 receptor (显示 AGTR1 抗体)-associated protein (显示 BCAP31 抗体) (ATRAP) and inactivation of AT1R-mediated p38 MAPK (显示 MAPK14 抗体) and STAT3 (显示 STAT3 抗体) signaling pathways, are involved cardiac hypertrophy.
Activation of aortic vascular ATRAP partially inhibits the Nox4 (显示 NOX4 抗体)/p22(phox (显示 CYBA 抗体))-ROS (显示 ROS1 抗体)-p38MAPK (显示 MAPK14 抗体)/JNK (显示 MAPK8 抗体) pathway and pathological aortic hypertrophy provoked by Ang II (显示 AGT 抗体)-mediated hypertension.
ATRAP, a directly interacting and functionally inhibiting molecule of AT1R, plays a protective role against the development of systemic insulin (显示 INS 抗体) resistance via regulatory effects on adipose tissue function.
AGTRAP expression is regulated by USF1 (显示 USF1 抗体) and USF2 (显示 USF2 抗体)
renal tubule-dominant ATRAP activation provokes no evident effects on blood pressure at baseline but exerts an inhibitory effect on the pathological elevation of blood pressure in response to angiotensin II stimulation
This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.
angiotensin II receptor-associated protein
, type-1 angiotensin II receptor-associated protein
, Type-1 angiotensin II receptor-associated protein
, AT1 receptor-associated protein
, ATI receptor-associated protein
, angiotensin II, type I receptor-associated protein
, AT1 receptor
, angiotensin II receptor, type I