anti-Angiomotin Like 2 (AMOTL2) 抗体

AMOTL2 belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. 再加上,我们可以发Angiomotin Like 2 蛋白 (4)Angiomotin Like 2 试剂盒 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
AMOTL2 51421 Q9Y2J4
AMOTL2 65157  
AMOTL2 56332 Q8K371
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Showing 10 out of 19 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB Western blot analysis of AMOTL2 Antibody (Center) (ABIN652806) in A375 cell line lysates (35 µg/lane). AMOTL2 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of AMOTL2 Antibody (Center) (ABIN652806) in mouse liver tissue lysates (35 µg/lane). AMOTL2 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 ICC, IF Immunocytochemistry/Immunofluorescence: AMOTL2 Antibody  - Staining of human cell line CACO-2 shows localization to centrosome & cell junctions. 100 μL Log in to see 10至13个工作日
$439.69
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非结合性 WB Western blot analysis of AMOTL2 Antibody in A375 cell line lysates (35ug/lane) Western blot analysis of AMOTL2 Antibody in mouse liver tissue lysates (35ug/lane) 400 μL Log in to see 2至3个工作日
$515.63
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非结合性 IHC, ELISA, WB   100 μg Log in to see 7至9个工作日
$390.50
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非结合性 WB   200 μL Log in to see 11至16个工作日
$594.00
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APC ELISA, WB   200 μL Log in to see 16 Days
$743.29
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FITC ELISA, WB   200 μL Log in to see 16 Days
$743.29
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HRP ELISA, WB   200 μL Log in to see 16 Days
$743.29
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PE ELISA, WB   200 μL Log in to see 16 Days
$743.29
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非结合性 WB   50 μg Log in to see 2至3个工作日
$473.93
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通过反应活性、应用领域、克隆类型和共轭标记 AMOTL2 抗体

特性 应用范围 宿主 克隆类型 标记
Human , ,


, , , , ,
Rat (Rattus)


Mouse (Murine) ,


引用最多的anti-Angiomotin Like 2 抗体

  1. Human Polyclonal AMOTL2 Primary Antibody for WB - ABIN652806 : Bratt, Wilson, Troyanovsky, Aase, Kessler, Van Meir, Holmgren, Meir: Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains. in Gene 2002 (PubMed)
    Show all 2 Pubmed References

更多抗Angiomotin Like 2的相互作用对抗体

Zebrafish Angiomotin Like 2 (AMOTL2) interaction partners

  1. Amotl2a function in the control of lateral line primordium cell proliferation is mediated together by the Hippo pathway effector Yap1 (显示 YAP1 抗体) and the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) effector Lef1 (显示 LEF1 抗体).

  2. amotL2 associates to the VE-cadherin adhesion complex where it couples adherens junctions to contractile actin fibres.

  3. We demonstrate that amotl2 knockdown in zebrafish wild-type embryos results in embryonic dorsalization, and this effect can be antagonized by co-knockdown of the dorsal inducer beta-catenin2.

  4. Amotl2 plays a pivotal role in polarity, migration and proliferation of angiogenic endothelial cells

  5. Amotl2 interacts preferentially with and facilitates translocation of the phosphorylated c-Src (显示 SRC 抗体), which may in turn regulate the membrane architecture. These data provide the first evidence that amotl2 is essential for cell movements in vertebrate embryos.

Human Angiomotin Like 2 (AMOTL2) interaction partners

  1. these results provide novel insights into a dual tumor suppressive function of AMOTL2 by targeting both YAP (显示 YAP1 抗体) and AKT (显示 AKT1 抗体) in liver size control and cancer prevention

  2. study reports for the first time that USP9X (显示 USP9X 抗体) is a deubiquitinase of Angiomotin-like 2 (AMOTL2) and that AMOTL2 mono-ubiquitination is required for YAP (显示 YAP1 抗体) inhibition

  3. mTORC2 (显示 CRTC2 抗体)-mediated phosphorylation of AMOTL2 blocks its ability to inhibit YAP (显示 YAP1 抗体) signaling.

  4. AmotL2 expression correlates with loss of tissue architecture in tumors from human breast and colon cancer patients.

  5. Scaffold proteins angiomotin (Amot (显示 AMOT 抗体)) and angiomotin (显示 AMOT 抗体)-related AmotL1 (显示 AMOTL1 抗体) and AmotL2 were recently identified as negative regulators of YAP (显示 YAP1 抗体) and TAZ (显示 TAZ 抗体) by preventing their nuclear translocation.

  6. These results collectively suggest that the Hippo pathway negatively regulates the actin-binding activity of Amot (显示 AMOT 抗体) family members through direct phosphorylation.

  7. These results demonstrate a role for Amotl2 in synaptic maturation and support the involvement of podosomes in this process.

  8. AMOTL2 interacts with TAZ (显示 TAZ 抗体) and modulates transcriptional activity of TAZ (显示 TAZ 抗体).

  9. AMOTL2 is as a novel activator of LATS2 (显示 LATS2 抗体).

  10. Amotl2 plays a pivotal role in polarity, migration and proliferation of angiogenic endothelial cells

Mouse (Murine) Angiomotin Like 2 (AMOTL2) interaction partners

  1. mTORC2 (显示 CRTC2 抗体)-mediated phosphorylation of AMOTL2 blocks its ability to inhibit YAP (显示 YAP1 抗体) signaling.

  2. AmotL2 disrupts apical-basal cell polarity and promotes tumor invasion.

  3. Amot (显示 AMOT 抗体), Amotl1 (显示 AMOTL1 抗体), and Amotl2 are differentially expressed in uterine cells during the peri (显示 POSTN 抗体)-implantation period.

  4. Amotl2 plays a pivotal role in polarity, migration and proliferation of angiogenic endothelial cells

  5. Data show that MUPP1 (显示 MPDZ 抗体) interacts with angiomotin (Amot (显示 AMOT 抗体)), JEAP (显示 AMOTL1 抗体)/Amot (显示 AMOT 抗体)-like 1 and MASCOT/Amot (显示 AMOT 抗体)-like 2, and that all the Amot (显示 AMOT 抗体)/JEAP (显示 AMOTL1 抗体) family proteins also interacted with Patj (显示 INADL 抗体), a close relative of MUPP1 (显示 MPDZ 抗体).

Angiomotin Like 2 (AMOTL2) 抗原简介

蛋白简介

Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motins protein family.

Gene names and symbols associated with anti-Angiomotin Like 2 (AMOTL2) 抗体

  • angiomotin like 1 (AMOTL1) 抗体
  • angiomotin like 2a (amotl2a) 抗体
  • angiomotin like 1 (amotl1) 抗体
  • angiomotin like 1 L homeolog (amotl1.L) 抗体
  • angiomotin like 2 (AMOTL2) 抗体
  • angiomotin like 2 (amotl2) 抗体
  • angiomotin like 2 (Amotl2) 抗体
  • angiomotin-like 2 (Amotl2) 抗体
  • amotl2 抗体
  • AW549739 抗体
  • C79691 抗体
  • cb308 抗体
  • DKFZp468L222 抗体
  • jeap 抗体
  • Lccp 抗体
  • MASCOT 抗体
  • mKIAA0989 抗体
  • sb:cb308 抗体
  • wu:fc41b07 抗体
  • wu:fc64c06 抗体

Protein level used designations for anti-Angiomotin Like 2 (AMOTL2) 抗体

angiomotin like 1 , angiomotin-like protein 1 , angiomotin like 2 , angiomotin-like 2a , angiomotin-like protein 1-like , angiomotin-like protein 2-like , Leman coiled-coil protein , angiomotin-like protein 2

GENE ID SPECIES
428091 Gallus gallus
451491 Pan troglodytes
558920 Danio rerio
100145436 Xenopus (Silurana) tropicalis
100158429 Xenopus laevis
100172648 Pongo abelii
100348712 Oryctolagus cuniculus
100475663 Ailuropoda melanoleuca
718868 Macaca mulatta
100379727 Xenopus (Silurana) tropicalis
100523696 Sus scrofa
460712 Pan troglodytes
100540953 Meleagris gallopavo
51421 Homo sapiens
65157 Rattus norvegicus
56332 Mus musculus
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