anti-Amyloid beta (Abeta) 抗体

Abeta encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. 再加上,我们可以发beta Amyloid 试剂盒 (12)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
Abeta 351 P05067
Abeta 54226 P08592
Abeta 11820 P12023
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antibodies-online.cn销售最多的anti-beta Amyloid 抗体

Showing 10 out of 277 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IHC, ELISA, WB 25 μL Log in to see 1至2个工作日
$135.00
详细
小鼠 非结合性 IHC, ELISA Abeta oligomer-specific antibody was adsorbed to Nunc-Immuno MaxiSorp plates (Nunc, Roskilde, Denmark) at 2 ug/ml in PBS. 1 ml of a 10 uM Aβ(1-42) sample containing a small fraction of Aβ-oligomers was separated using a superdex G75 (10/30) column. Aβ-fractions collected from the SEC were allowed to bind to OMAB plates for 20 minutes at 0°C. All fractions were analyzed and bound Aβ was detected using a polyclonal rabbit anti-Aβ antibody (ABIN249343) at a 1:1000 dilution followed by an anti-rabbit HRP-conjugated secondary antibody at a 1:5000 dilution (GE healthcare). ECBlue (Medicago, Uppsala, Sweden) was used as a substrate for HRP and the signal was detected by measuring the absorbance at 450 nm. Blocking solution and antibody-dilutions were made with 5% Non-fat dry milk in PBST and all washes were performed with PBS containing 0.1% Tween-20 (PBST). 10 µm of coronal sections from fresh-frozen transgenic mouse brain mutant (A) and wild type (B). Post-fixation in 4% formaldehyde solution, 5 min. OMAB antibody diluted 1:500, incubation at 4ºC ON. Mouse on mouse HRP-Polymer kit according to company instructions. Biocare Medical: BC-MM510 (Histolab) DAB substrate kit for peroxidase. Vector Laboratories: SK-4100 (ImmunKemi) Counterstained with Mayers HTX. 50 μg Log in to see 6至8个工作日
$683.76
详细
小鸡 非结合性 IHC, WB Immunohistochemical analysis of Beta Amyloid (pT743) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Beta Amyloid (pT743) expression in MCF7 colchicine-treated (A), mouse liver (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$575.00
详细
小鼠 非结合性 ELISA, ICC, IF, IHC, IHC (ff), IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - Immunofluorescent detection of beta Amyloid with MOAB-2 in the subiculim of 1-, 2- and 4- month old 5xFAD mice. Scale bar 20 um (from PMID: 22423893). Immunohistochemistry: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - IHC analysis of beta Amyloid on normal mouse brain (left) and 5xFAD mouse brain (right) using DAB with hematoxylin counterstain. The MOAB-2 antibody was used at 1:20 on normal mouse brain and at 1:400 on 5xFAD mouse brain. 0.1 mL Log in to see 7至9个工作日
$473.81
详细
小鼠 山羊 非结合性 ELISA, WB Western Blot: beta Amyloid Antibody [NBP1-97755] - (0.03ug/ml) Analysis of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$408.19
详细
非结合性 ELISA, IHC, IHC (p), WB Immunohistochemistry: beta Amyloid Antibody [NBP2-25093] - Analysis of APP in human brain tissue with APP antibody at 2.5 ug/ml. Immunohistochemistry-Paraffin: beta Amyloid Antibody [NBP2-25093] - Human brain (Alzheimer's disease) tissue with APP antibody at 10 ug/mL. 0.1 mg Log in to see 8至11个工作日
$447.56
详细
Cow 非结合性 ELISA, ICC, IF, IHC, Act (ligand), WB Western Blot: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Lane 1-10: beta Amyloid pyro E3 peptide. Load: 1 ug per lane 1-2, 0.2 ug per lane 3-4, 0.05 ug per lane 5-6, 0.01 ug per lane 7-8, 0.005 ug per lane 9-10. Primary antibody: Beta Amyloid pyro E3 antibody at 0.5 ug/mL for overnight at 4C. Secondary antibody: IRDye800 rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4C. Predicted/Observed size: 86.9 kDa for beta Amyloid pyro E3 peptide. Cross reactivity with Beta Amyloid 3 peptide is >1000 fold below pyrE3 reactivity and contains no reactivity towards the Beta Amyloid 42 A beta peptide (data not shown). Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE3Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44048 antibody. 0.05 mg Log in to see 7至9个工作日
$500.06
详细
Fruit Fly 非结合性 ELISA, ICC, IF, IHC, Act (ligand), WB Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - beta-amyloid (pyroglu11) NBP1-44070 in red (left) co-labeled with 6E10 in green (middle) and merge (right). Image from verified customer review. Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE11Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44070 antibody. 0.05 mg Log in to see 7至9个工作日
$538.13
详细
非结合性 EIA, IF, IHC (p), WB 0.1 mg Log in to see 6至8个工作日
$419.10
详细
非结合性 ELISA, IF, IHC, WB 100 μL Log in to see 16 Days
$175.80
详细

通过反应活性、应用领域、克隆类型和共轭标记 Abeta 抗体

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引用最多的anti-beta Amyloid 抗体

  1. Human Monoclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284085 : Youmans, Tai, Kanekiyo, Stine, Michon, Nwabuisi-Heath, Manelli, Fu, Riordan, Eimer, Binder, Bu, Yu, Hartley, LaDu: Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. in Molecular neurodegeneration 2012 (PubMed)
    Show all 8 Pubmed References

  2. Cow (Bovine) Polyclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284076 : He, Barrow: The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta. in Biochemistry 1999 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal beta Amyloid Primary Antibody for ELISA, IF - ABIN5508784 : Markoutsa, Papadia, Clemente, Flores, Antimisiaris: Anti-Aβ-MAb and dually decorated nanoliposomes: effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012 (PubMed)
    Show all 4 Pubmed References

  4. Human beta Amyloid Primary Antibody for ELISA (Capture), IF - ABIN1110165 : Levites, Jansen, Smithson, Dakin, Holloway, Das, Golde et al.: Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor ... in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 3 Pubmed References

  5. Fruit Fly (Drosophila melanogaster) Polyclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284077 : Youssef, Florent-Béchard, Malaplate-Armand, Koziel, Bihain, Olivier, Leininger-Muller, Kriem, Oster, Pillot: N-truncated amyloid-beta oligomers induce learning impairment and neuronal apoptosis. in Neurobiology of aging 2008 (PubMed)
    Show all 3 Pubmed References

  6. Human beta Amyloid Primary Antibody for IF, IP - ABIN1110164 : Levites, Smithson, Price, Dakin, Yuan, Sierks, Kim, McGowan, Reed, Rosenberry, Das, Golde: Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 (PubMed)
    Show all 2 Pubmed References

  7. Human beta Amyloid Primary Antibody for ELISA (Capture), ELISA (Detection) - ABIN1110166 : Levites, Das, Price, Rochette, Kostura, McGowan, Murphy, Golde: Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model. in The Journal of clinical investigation 2006 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal beta Amyloid Primary Antibody for IHC (fro), IHC (p) - ABIN2477631 : Romaguera, Grimalt, Vilaplana: Eczematous and purpuric allergic contact dermatitis from boots. in Contact dermatitis 1990 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal beta Amyloid Primary Antibody for ELISA, WB - ABIN1573928 : Jia, Liu, Song, Pan, Chen, Cui, Wang: Berberine suppresses amyloid-beta-induced inflammatory response in microglia by inhibiting nuclear factor-kappaB and mitogen-activated protein kinase signalling pathways. in The Journal of pharmacy and pharmacology 2012 (PubMed)

更多抗beta Amyloid的相互作用对抗体

Human Amyloid beta (Abeta) interaction partners

  1. a 99-aa C-terminal fragment of APP (显示 APP 抗体),C99, in addition to its localization in endosomes, can also be found in mitochondria-associated endoplasmic reticulum (ER) membranes, where it is normally processed rapidly by gamma-secretase.

  2. Photoinduced electrons of g-C3 N4 generate reactive oxygen resulting in photooxidation of amyloid peptides that blocks Abeta (显示 APP 抗体) aggregation.

  3. Studies indicate that amyloid precursor-like protein 2 (APLP2 (显示 APLP2 抗体)) and amyloid precursor protein (APP (显示 APP 抗体)) are linked to increased tumor cell proliferation, migration, and invasion.

  4. the precise and complex regulation of APP (显示 APP 抗体) phosphorylation, abundance, and cleavage impacts the generation of nuclear spheres, which are under discussion of being of relevance in neurodegeneration and dementia.

  5. Decreased lipoprotein endocytosis and transcytosis of APP (显示 APP 抗体) to the axon suggest that a neuron-specific impairment in endocytic axonal delivery of lipoproteins and other key materials might compromise synaptic maintenance in familial Alzheimer's disease.

  6. Our results suggested that hAPP was more likely an important factor inhibiting adult neurogenesis, and Abeta (显示 APP 抗体) was not the major factor affecting neurogenesis in the adult hippocampus of hAPP mice.

  7. the AOEP2 peptide binds to Abeta (显示 APP 抗体) monomers and inhibits the formation of Abeta (显示 APP 抗体) oligomers and beta-sheet structure, reduces Abeta42-induced neurotoxicity, and decreases the release of proinflammatory cytokines.

  8. BECN1 (显示 BECN1 抗体)-APP (显示 APP 抗体) association and BECN1 (显示 BECN1 抗体)-dependent APP (显示 APP 抗体) endocytosis and degradative trafficking were negatively regulated by active AKT (显示 AKT1 抗体).

  9. The authors demonstrate that pathological PS1 (显示 PSEN1 抗体) loss-of-function impinges on neurite formation through a selective APP (显示 APP 抗体) gain-of-function that could impact on axodendritic connectivity and contribute to aberrant axonal sprouting observed in Alzheimer's disease patients.

  10. These findings thus provide new insights into Abeta (显示 APP 抗体)-induced mitochondrial defects that may contribute to neuronal dysfunction and Alzheimer's disease pathogenesis.

Mouse (Murine) Amyloid beta (Abeta) interaction partners

  1. a 99-aa C-terminal fragment of APP (显示 APP 抗体),C99, in addition to its localization in endosomes, can also be found in mitochondria-associated endoplasmic reticulum (ER) membranes, where it is normally processed rapidly by gamma-secretase.

  2. The authors concluded that the FcgammaRIIb-SHIP2 (显示 INPPL1 抗体) axis links Abeta (显示 APP 抗体) neurotoxicity to tau pathology by dysregulating phosphoinositide metabolism, providing insight into therapeutic potential against Alzheimer's disease.

  3. results suggest that PrP(C (显示 PRNP 抗体)) recognizes structural features common to both Abeta (显示 APP 抗体) oligomers and fibril ends and that this interaction could contribute to the neurotoxic effect of Abeta (显示 APP 抗体) aggregates.

  4. Transmembrane APP (显示 APP 抗体) expressed by tumor cells binds to endothelial DR6 (显示 TNFRSF21 抗体) to trigger necroptosis, and targeting DR6 (显示 TNFRSF21 抗体)-mediated endothelial cell necroptosis may be a potential therapeutic strategy

  5. Our study provides the first direct evidence that Abeta, an AD-linked factor, is associated to the pathogenesis of ALS and provides molecular clues to understand common aggregation mechanisms in the pathogenesis of neurodegenerative diseases.

  6. Although hyperactivity and hypersynchronicity were respectively detected in mice expressing the PS2 (显示 PDCD6 抗体)-N141I or the APP (显示 APP 抗体) Swedish mutant alone, the increase in cross-frequency coupling specifically characterized the 6-month-old PS2APP mice, just before the surge of the cognitive decline

  7. these results uncover a novel role for mDia1 in Abeta (显示 APP 抗体)-mediated synaptotoxicity and demonstrate that inhibition of MT dynamics and accumulation of PTMs (显示 PTMS 抗体) are driving factors for the induction of tau-mediated neuronal damage.

  8. APP (显示 APP 抗体) and its metabolites are capable of influencing the basic physiology of the pancreas.

  9. treatment of APP/E4/Abca1+/- mice with liver X receptor (LXR) agonist T0 ameliorates APOE4-induced Alzheimer's disease (AD)-like pathology and therefore targeting the LXR-ABCA1-APOE regulatory axis could be effective as a potential therapeutic approach in AD patients, carriers of APOEepsilon4

  10. These results provide evidence supporting a key role for the p38 MAPK (显示 MAPK14 抗体) signaling pathway which is involved in the regulation of Abeta1-42 internalization in the parietal cortex and hippocampus of mouse through LRP1 (显示 LRP1 抗体) in vivo.

beta Amyloid (Abeta) 抗原简介

蛋白简介

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Gene names and symbols associated with anti-Amyloid beta (Abeta) 抗体

  • amyloid beta precursor protein (APP) 抗体
  • amyloid beta precursor protein (app) 抗体
  • amyloid beta precursor protein (App) 抗体
  • amyloid beta (A4) precursor protein (App) 抗体
  • aaa 抗体
  • Abeta 抗体
  • Abpp 抗体
  • ad1 抗体
  • Adap 抗体
  • Ag 抗体
  • appi 抗体
  • betaApp 抗体
  • ctfgamma 抗体
  • Cvap 抗体
  • E030013M08Rik 抗体
  • PN-II 抗体
  • pn2 抗体

Protein level used designations for anti-Amyloid beta (Abeta) 抗体

alzheimer disease amyloid protein , amyloid beta A4 protein , beta-amyloid peptide , cerebral vascular amyloid peptide , peptidase nexin-II , preA4 , protease nexin-II , amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease) , amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) , beta-amyloid precursor protein , alzheimer disease amyloid A4 protein homolog , amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) , ABPP , AG , amyloid A4 , amyloidogenic glycoprotein , appican , protease nexin II

GENE ID SPECIES
351 Homo sapiens
448208 Xenopus (Silurana) tropicalis
100427716 Macaca mulatta
54226 Rattus norvegicus
11820 Mus musculus
anti-beta Amyloid (Abeta) 抗体 精选生产商
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