Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) ELISA试剂盒

AP3B1 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. 再加上,我们可以发AP3B1 抗体 (38)AP3B1 蛋白 (3)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
AP3B1 8546 O00203
小鼠 AP3B1 AP3B1 11774 Q9Z1T1
大鼠 AP3B1 AP3B1 309969  

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Human Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) interaction partners

  1. Synergistic defects of UNC13D (显示 UNC13D ELISA试剂盒) and AP3B1 leading to adult hemophagocytic lymphohistiocytosis.

  2. Using a co-affinity purification strategy, authors have identified the beta subunit (显示 POLG ELISA试剂盒) of the AP-3 adapter protein (显示 TOLLIP ELISA试剂盒) complex, AP3B1, as a binding partner for the M proteins of the zoonotic paramyxoviruses Nipah virus and Hendra virus.

  3. Data indicate that RUN and FYVE domain protein Rabip4'(RUFY1 (显示 RUFY1 ELISA试剂盒)) interacts specifically and directly with adaptor protein complex AP-3.

  4. The study provides a description of two unrelated individuals with Hermansky Pudlak syndrome type 2 associated with novel mutations in AP3B1.

  5. diphosphoinositol pentakisphosphate-mediated pyrophosphorylation of AP3B1 modulates the interaction with Kif3A (显示 KIF3A ELISA试剂盒) and, as a consequence, affects the release of HIV-1 virus-like particles.

  6. Two nonsense mutations in ADTB3A, C1578T (R-->X) and G2028T (E-->X), result in lack of ADTB3A mRNA and beta3A (显示 BHLHE22 ELISA试剂盒) protein production and a severe, G-CSF (显示 CSF3 ELISA试剂盒)-responsive neutropenia in addition to oculocutaneous albinism and platelet storage pool deficiency.

  7. Description of mutations in HPS (显示 HPS1 ELISA试剂盒) genes that cause Hermansky-Pudlak syndrome (review)

  8. We defined a homozygous genomic deletion in AP3B1, the gene encoding the beta chain of the adaptor protein-3 (AP-3) complex. The mutation leads to in-frame skipping of exon 15 and thus perturbs proper assembly of the heterotetrameric AP-3 complex.

  9. A novel homozygous mutation in AP3B1 was detected in a 2-year-old patient with oculocutaneous albinism and immunodeficiency with Hermansky-Pudlak syndrome type II and eventual acute fatal hemophagocytic lymphohistiocytosis.

  10. Mutations in AP3B1 is not associated with familial hemophagocytic lymphohistiocytosis

Mouse (Murine) Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) interaction partners

  1. HIV-2 particle release was dependent on the adaptor protein complex AP-3 and the newly identified AP-5 (显示 AP5B1 ELISA试剂盒) complex, but much less so on AP-1 (显示 JUN ELISA试剂盒).

  2. Data show that cytokine activation as a result of toll-like receptor 2 (TLR2 (显示 TLR2 ELISA试剂盒)) stimulation occurs at different intracellular locations and is mediated by the phagosomal trafficking molecule adaptor protein-3 (显示 HSPB3 ELISA试剂盒) (AP-3).

  3. Our study indicates that Ap3b1 gene play distinct roles in melanin production and tyrosinase (显示 TYR ELISA试剂盒) distribution compared with Hps1 gene.

  4. we show that loss of the related adaptor protein AP-1 has a similar effect on regulated secretion but exacerbates the effect of AP-3 RNAi, suggesting distinct roles for the two adaptors in the regulated secretory pathway.

  5. Data suggest functional links between OCA2 and the BLOC-1, BLOC-2, and AP-3 protein complexes involved in melanosome biogenesis.

  6. The identification of the feeble mutation led to our subsequent observations that AP-3, as well as the BLOC-1 (显示 PLDN ELISA试剂盒) and BLOC-2 (显示 HPS6 ELISA试剂盒) are essential for plasmacytoid dendritic cells signaling through TLR7 (显示 TLR7 ELISA试剂盒) and TLR9 (显示 TLR9 ELISA试剂盒).

  7. TLR9 (显示 TLR9 ELISA试剂盒) signals leading to activation of IFN I, require TLR9 (显示 TLR9 ELISA试剂盒) trafficking from endosomes to lysosome-related organelle; adapter protein (显示 GRB10 ELISA试剂盒)-3 (显示 HSPB3 ELISA试剂盒) identified as protein complex responsible for trafficking of TLR9 (显示 TLR9 ELISA试剂盒) to this subcellular compartment

  8. AP-3 mediates the intracellular trafficking of CD1d (显示 CD1D ELISA试剂盒) to lysosomes for sampling of lipid antigens (Ags (显示 GLA ELISA试剂盒)) involved in self-Ag presentation and thymocyte-positive selection.

  9. AP-3 requirement is a particular attribute of the CD1d (显示 CD1D ELISA试剂盒) pathway in mice and that, although MHC class II molecules and CD1d (显示 CD1D ELISA试剂盒) are both found in late endosomes or lysosomes, different pathways mediate their intracellular trafficking

  10. AP-3B (显示 AP3M2 ELISA试剂盒) plays a critical role in the normal formation and function of a subset of synaptic vesicles

AP3B1 抗原简介

Antigen Summary

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with AP3B1

  • adaptor-related protein complex 3, beta 1 subunit (ap3b1) 抗体
  • adaptor-related protein complex 3, beta 1 subunit (AP3B1) 抗体
  • adaptor-related protein complex 3, beta 1 subunit (LOC100350054) 抗体
  • adaptor-related protein complex 3, beta 1 subunit (Ap3b1) 抗体
  • ADTB3 抗体
  • ADTB3A 抗体
  • AP-3 抗体
  • AP3B1 抗体
  • AU015684 抗体
  • beta3A 抗体
  • C78395 抗体
  • cb964 抗体
  • HPS 抗体
  • Hps2 抗体
  • pe 抗体
  • pearl 抗体
  • rim2 抗体

Protein level used designations for AP3B1

adaptor-related protein complex 3, beta 1 subunit , AP-3 complex subunit beta-1 , adaptor-related protein complex 3, beta-1 subunit , AP-3 complex subunit beta-1-like , AP-3 complex beta-3A subunit , adaptor protein complex AP-3 subunit beta-1 , beta-3A-adaptin , clathrin assembly protein complex 3 beta-1 large chain , adapter-related protein complex 3 subunit beta-1 , adaptor protein complex AP-3 beta-1 subunit , adaptor-related protein complex AP-3, beta 1 subunit , beta3A-adaptin , recombination induced mutation 2 , adaptor-related protein complex AP3 beta 1 subunit

GENE ID SPECIES
443724 Xenopus laevis
386770 Danio rerio
427646 Gallus gallus
461789 Pan troglodytes
100019944 Monodelphis domestica
100049670 Sus scrofa
100065436 Equus caballus
100226392 Taeniopygia guttata
100350054 Oryctolagus cuniculus
100397094 Callithrix jacchus
100584809 Nomascus leucogenys
708754 Macaca mulatta
8546 Homo sapiens
11774 Mus musculus
309969 Rattus norvegicus
767602 Bos taurus
403459 Canis lupus familiaris
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