Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) ELISA试剂盒

The protein encoded by APPL2 is one of two effectors of the small GTPase RAB5A/Rab5, which are involved in a signal transduction pathway. 再加上,我们可以发Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 抗体 (33)Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 蛋白 (5)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
大鼠 APPL2 APPL2 362860  
 APPL2 APPL2 55198 Q8NEU8
小鼠 APPL2 APPL2 216190 Q8K3G9

适于 Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 相互作用对的更多 ELISA 试剂盒

Human Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) interaction partners

  1. Results show the suppressive effect of OCC-1 RNA on transcription level of the APPL2 (显示 APLP2 ELISA试剂盒) gene provides a putative colorectal neoplasm progression index.

  2. Data show that signal transducing adaptor proteins APPL1 and APPL2 are required for TGFbeta-induced nuclear translocation of TGFbeta type I receptor (TbetaRI)-ICD and for cancer cell invasiveness of prostate and breast cancer cell lines.

  3. ATM (显示 ATM ELISA试剂盒) is the central modulator of APPL (显示 APPL1 ELISA试剂盒)-mediated effects on radiosensitivity and DNA repair.

  4. It concludes that APPL2 (显示 APLP2 ELISA试剂盒)(PH) binding to BAR domain and Reptin (显示 RUVBL2 ELISA试剂盒) is mutually exclusive which regulates the nucleocytoplasmic shuttling of Reptin (显示 RUVBL2 ELISA试剂盒).

  5. C-APPL1 (显示 APPL1 ELISA试剂盒)/A-APPL2 (显示 APLP2 ELISA试剂盒) allele combination is associated with non-alcoholic fatty liver disease occurrence, with a more severe hepatic steatosis grade and with a reduced adiponectin (显示 ADIPOQ ELISA试剂盒) cytoprotective effect on liver.

  6. Data indicate that a high level of APPL2 (显示 APLP2 ELISA试剂盒) protein might enhance glioblastoma growth by maintaining low expression level of genes responsible for cell death induction.

  7. analysis of APPL1 (显示 APPL1 ELISA试剂盒) and APPL2 (显示 APLP2 ELISA试剂盒) proteins and their interaction with Rab (显示 HRB ELISA试剂盒)

  8. Genetic variation(s) in APPL1 (显示 APPL1 ELISA试剂盒)/2 may be associated with CAD (显示 CAD ELISA试剂盒) risk in T2DM in Chinese population.

  9. Data suggest that although annexin A2 (显示 ANXA2 ELISA试剂盒) is not an exclusive marker of APPL1 (显示 APPL1 ELISA试剂盒)/2 endosomes, it has an important function in membrane recruitment of APPL (显示 APPL1 ELISA试剂盒) proteins, acting in parallel to Rab5 (显示 RAB5A ELISA试剂盒).

  10. significant fluorescence resonance energy transfer between APPL (显示 APPL1 ELISA试剂盒) minimal BAR domain FRET pairs

Mouse (Murine) Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) interaction partners

  1. Appl1 (显示 APPL1 ELISA试剂盒)/2-null mouse embryonic fibroblasts exhibited defects in HGF (显示 HGF ELISA试剂盒)-induced Akt (显示 AKT1 ELISA试剂盒) activation, migration, and invasion.

  2. Rab31 (显示 RAB31 ELISA试剂盒), with APPL2 as its effector, play a role in FcgammaR-mediated phagocytosis through PI3K/Akt (显示 AKT1 ELISA试剂盒) signaling in macrophages.

Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) 抗原简介

Antigen Summary

The protein encoded by this gene is one of two effectors of the small GTPase RAB5A/Rab5, which are involved in a signal transduction pathway. Both effectors contain an N-terminal Bin/Amphiphysin/Rvs (BAR) domain, a central pleckstrin homology (PH) domain, and a C-terminal phosphotyrosine binding (PTB) domain, and they bind the Rab5 through the BAR domain. They are associated with endosomal membranes and can be translocated to the nucleus in response to the EGF stimulus. They interact with the NuRD/MeCP1 complex (nucleosome remodeling and deacetylase /methyl-CpG-binding protein 1 complex) and are required for efficient cell proliferation. A chromosomal aberration t(12\;22)(q24.1\;q13.3) involving this gene and the PSAP2 gene results in 22q13.3 deletion syndrome, also known as Phelan-McDermid syndrome.

Gene names and symbols associated with APPL2

  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (Appl2) 抗体
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (APPL2) 抗体
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (appl2) 抗体
  • amyloid beta (A4) precursor-like protein 2 (APLP2) 抗体
  • APPL2 抗体
  • Dip3b 抗体
  • DIP13B 抗体
  • MGC84621 抗体
  • RGD1563028 抗体

Protein level used designations for APPL2

DCC-interacting protein 13-beta , adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 , amyloid beta (A4) precursor-like protein 2 , DIP13 beta , adapter protein containing PH domain, PTB domain and leucine zipper motif 2 , Dip3 beta , dip13-beta

GENE ID SPECIES
362860 Rattus norvegicus
418075 Gallus gallus
447596 Xenopus laevis
515605 Bos taurus
100000135 Danio rerio
100127202 Xenopus (Silurana) tropicalis
100545199 Meleagris gallopavo
100563730 Anolis carolinensis
100604575 Nomascus leucogenys
55198 Homo sapiens
216190 Mus musculus
您还需要查找其他产品吗?