ATF6 抗体
(Activating Transcription Factor 6 (ATF6))
This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011].
recommended
recommended
recommended
Verified ATF6 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
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Popular ATF6 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
- (9)
Cat. No.
ABIN1512605
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7440587
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, FACS
Validations
- (5)
Cat. No.
ABIN1590087
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Validations
- (2)
- (3)
Cat. No.
ABIN732293
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (1)
- (4)
Cat. No.
ABIN652625
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN3028449
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7440068
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (3)
Cat. No.
ABIN524861
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ICC
Validations
- (1)
- (2)
Cat. No.
ABIN541510
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (5)
- (3)
Cat. No.
ABIN2451924
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IP
Validations
- (3)
- (3)
Cat. No.
ABIN2451923
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN4996973
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7148805
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6746985
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN524859
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ATF6 抗体
: "Ebola Virus Activates IRE1α-Dependent XBP1u Splicing." in: Viruses, Vol. 15, Issue 1, (2023) (PubMed).: "Counteracting Cisplatin-Induced Testicular Damages by Natural Polyphenol Constituent Honokiol." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).
: "Loss of Calreticulin Uncovers a Critical Role for Calcium in Regulating Cellular Lipid Homeostasis." in: Scientific reports, Vol. 7, Issue 1, pp. 5941, (2019) (PubMed).
: "EMC3 coordinates surfactant protein and lipid homeostasis required for respiration." in: The Journal of clinical investigation, Vol. 127, Issue 12, pp. 4314-4325, (2019) (PubMed).
: "Expressions of ATF6, XBP1, and GRP78 in normal tissue, atypical adenomatous hyperplasia, and adenocarcinoma of the lung." in: Human pathology, Vol. 83, pp. 22-28, (2019) (PubMed).
: "IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages." in: Immunology and cell biology, Vol. 97, Issue 2, pp. 203-217, (2019) (PubMed).
: "Imatinib‑induced apoptosis of gastric cancer cells is mediated by endoplasmic reticulum stress." in: Oncology reports, Vol. 41, Issue 3, pp. 1616-1626, (2019) (PubMed).
: "The effect of Tmem135 overexpression on the mouse heart." in: PLoS ONE, Vol. 13, Issue 8, pp. e0201986, (2019) (PubMed).
: "Tauroursodeoxycholic acid attenuates cyclosporine-induced renal fibrogenesis in the mouse model." in: Biochimica et biophysica acta. General subjects, Vol. 1863, Issue 7, pp. 1210-1216, (2019) (PubMed).
: "C/EBPβ mediates palmitate-induced musclin expression via the regulation of PERK/ATF4 pathways in myotubes." in: American journal of physiology. Endocrinology and metabolism, Vol. 316, Issue 6, pp. E1081-E1092, (2019) (PubMed).
Aliases for ATF6 抗体
activating transcription factor 6 (ATF6) 抗体uncharacterized LOC412432 (LOC412432) 抗体
activating transcription factor 6 S homeolog (atf6.S) 抗体
cyclic AMP-dependent transcription factor ATF-6 alpha (LOC100122162) 抗体
activating transcription factor 6 (Atf6) 抗体
9130025P16Rik 抗体
9630036G24 抗体
AA789574 抗体
ATF-6-like 抗体
ATF6 抗体
Atf6 抗体
ATF6A 抗体
Atf6alpha 抗体
ESTM49 抗体
GB16435 抗体
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