anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) 抗体

The protein encoded by ABCC3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发ABCC3 试剂盒 (20)ABCC3 蛋白 (9)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ABCC3 8714 O15438
ABCC3 76408 B2RX12
ABCC3 140668 O88563

antibodies-online.cn销售最多的anti-ABCC3 抗体

Showing 10 out of 80 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB WB Suggested Anti-ABCC3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 FACS, IHC (p), WB ABCC3 Antibody (Center) (ABIN654103) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 5至8个工作日
¥2,325.14
详细
非结合性 EIA, IHC (p), WB ABCC3 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. ABCC3 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCC3 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 29至35个工作日
¥4,086.26
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小鼠 非结合性 IHC (fro), IF, WB   1 mL Log in to see 29至35个工作日
¥4,590.71
详细
非结合性 ELISA, WB Western Blot (WB) analysis of specific cells using MRP3 Polyclonal Antibody. 100 μL Log in to see 34至38个工作日
¥4,371.67
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非结合性 IP, WB Western blot analysis of MRP3 expression in HepG2 (A), MCF7 (B), MDAMB435 (C) whole cell lysates. 200 μL Log in to see 7至8个工作日
¥3,941.44
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非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
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小鼠 非结合性 IHC (fro), IF, WB   500 μL Log in to see 33至42个工作日
¥5,067.16
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非结合性 ELISA, WB 50 μg Log in to see 24至29个工作日
¥4,312.06
详细
非结合性 WB Western blot analysis of extracts of various cells, using ABCC3 antibody. 100 μL Log in to see 34至38个工作日
¥2,882.69
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通过反应活性、应用领域、克隆类型和共轭标记 ABCC3 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-ABCC3 抗体

  1. Human Polyclonal ABCC3 Primary Antibody for EIA, IHC (p) - ABIN950200 : Hoffman, Urbatsch, Vogel: Nucleotide binding to the human multidrug resistance protein 3, MRP3. in The protein journal 2010 (PubMed)
    Show all 5 references for 950200

  2. Dog (Canine) Polyclonal ABCC3 Primary Antibody for WB - ABIN2781505 : Müller, Asher, Heled, Cohen, Risch, Rund: Polymorphisms in transporter and phase II metabolism genes as potential modifiers of the predisposition to and treatment outcome of de novo acute myeloid leukemia in Israeli ethnic groups. in Leukemia research 2008 (PubMed)
    Show all 2 references for 2781505

  3. Human Monoclonal ABCC3 Primary Antibody for IHC (fro), IF - ABIN1105171 : Kool, de Haas, Scheffer, Scheper, van Eijk, Juijn, Baas, Borst: Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. in Cancer research 1997 (PubMed)
    Show all 2 references for 1105171

  4. Human Polyclonal ABCC3 Primary Antibody for FACS, IHC (p) - ABIN654103 : Moyer, Sun, Batzler, Li, Schaid, Yang, Weinshilboum: Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010 (PubMed)

更多抗ABCC3的相互作用对抗体

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) interaction partners

  1. miR (显示 MLXIP 抗体)-148a-siRNA and rifampin inhibited estradiol upregulation of MRP3 expression. miR (显示 MLXIP 抗体)-148a may be involved in the estrogen induction in intrahepatic cholestasis of pregnancy via PXR (显示 NR1I2 抗体) signaling. MRP3 may be involved.

  2. ABCC3 genetic variants are associated with postoperative morphine-induced respiratory depression and morphine pharmacokinetics in children.

  3. PXR (显示 NR1I2 抗体) is a potential biomarker for predicting outcome and activates MRP3 transcription by directly binding to its promoter resulting in an increased L-OHP efflux capacity, and resistance to L-OHP or platinum drugs in CRC (显示 CALR 抗体).

  4. This study highlights the importance of ABCC3 transporters in drug resistance to chemotherapy in the context of breast cancer.

  5. Wnt (显示 WNT2 抗体) signaling regulates ABCC3 expression in colon cancer cells, with the ABCC3 locus being a target of the transcription factors TCF7L2 (显示 TCF7L2 抗体) and beta-catenin (显示 CTNNB1 抗体).

  6. ABCC3 is an important oncoprotein involved in glycolysis and drug resistance

  7. This report is the first to describe liver overexpression of Abcc3 during the cancer initiation, promotion, and progression periods in rat hepatocarcinogenesis model and in human hepatocellular carcinoma

  8. High MRP expression is associated with sorafenib resistance in hepatocellular carcinoma.

  9. ABCC3 rs4148416 polymorphism was significantly associated with poor osteosarcoma response.

  10. Data suggest that hepatic expression of MRP3 is up-regulated and canalicular localization of MRP2 (显示 ABCC2 抗体) is altered in pediatric patients with advanced nonalcoholic steatohepatitis; these alterations may be involved in changes observed in drug metabolism.

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) interaction partners

  1. data show that this transporter activity is involved in ABCC3-induced senescence, demonstrating that this protein has a complex role in cancer, since its loss of function may promote escape from OIS and tumor formation

  2. Transport of cefadroxil by ABCC3 and ABCC4 (显示 ABCC4 抗体) was saturable with K(m) values of 2.5 +/- 0.7 and 0.25 +/- 0.07 mM, respectively.

  3. role of the bile acid membrane transporter Mrp3 (Abcc3), which is expressed in the liver and gut (显示 GUSB 抗体), in the hepatic growth response elicited by bile acids and in liver regeneration after partial hepatectomy

  4. Both Abcc2 (显示 ABCC2 抗体) and Abcc3 significantly influenced the PK properties of MTX (显示 MTX1 抗体).

  5. InsP(3)R2-mediated Ca(2 (显示 CA2 抗体)+) signals enhance organic anion secretion into bile by targeting Mrp2 (显示 ABCC2 抗体) to the canalicular membrane.

  6. Data show that Abcc2 (显示 ABCC2 抗体), Abcc3, and Abcg2 (显示 ABCG2 抗体) together mediate the rapid elimination of MTX (显示 MTX1 抗体) and 7OH-MTX (显示 MTX1 抗体).

  7. These results suggest that Mrp3 plays major roles in the efflux transport of various glucuronide conjugates from the enterocytes to the portal blood in the small intestine together with unknown transporter(s)

  8. induction of Mrp3 plays a significant role in hepatocyte protection during obstructive cholestasis

  9. VDR (显示 CYP27B1 抗体) has a role in the protection of colon cells from bile acid toxicity through regulation of the Mrp3 expression

  10. Mrp3 does not have a major role in bile salt physiology, but is involved in the transport of glucuronidated compounds, which could include glucuronidated bile salts in humans

ABCC3 抗原简介

蛋白简介

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined\; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized.

Gene names and symbols associated with ABCC3

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (ABCC3) 抗体
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (Abcc3) 抗体
  • ATP-binding cassette, subfamily C (CFTR/MRP), member 3 (Abcc3) 抗体
  • 1700019L09Rik 抗体
  • ABC31 抗体
  • cMOAT2 抗体
  • EST90757 抗体
  • Mlp2 抗体
  • MOAT-D 抗体
  • Mrp3 抗体

Protein level used designations for ABCC3

ATP-binding cassette sub-family C member 3 , canalicular multispecific organic anion transporter 2 , canicular multispecific organic anion transporter , multi-specific organic anion transporter D , multidrug resistance associated protein , multidrug resistance-associated protein 3 , ATP-binding cassette protein C3 , ATP-binding cassette transporter , transporter , ATP-binding cassette, sub-family C (CFTR/MRP), member 3 , MLP-2 , MRP-like protein 2 , multidrug resistance protein 3 , organic anion transporter

GENE ID SPECIES
8714 Homo sapiens
76408 Mus musculus
140668 Rattus norvegicus
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