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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) 抗体

The membrane-associated protein encoded by ABCB1B is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B 蛋白 (11)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ABCB1B 5243 P08183
ABCB1B 18669 P06795
ABCB1B 24646  

antibodies-online.cn销售最多的anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B 抗体

Showing 10 out of 31 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody (ABIN670161), Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody , Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 9至12个工作日
¥2,709.56
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非结合性 ICC, IF, IHC (p) Immunofluorescence analysis of mouse kidney tissue using anti-MDR1 (dilution of primary antibody - 1:1000) Immunohistochemical staining of paraffin embedded mouse kidney tissue using anti-MDR1 (primary antibody at 1:1000) 100 μg Log in to see 29至38个工作日
¥3,117.66
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小鼠 非结合性 IF, IP, WB   100 μL Log in to see 34至38个工作日
¥2,807.65
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小鼠 非结合性 FACS, IF, IHC, WB   500 μL Log in to see 33至42个工作日
¥6,067.47
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小鼠 非结合性 IC, IHC, WB   100 μg Log in to see 33至42个工作日
¥4,571.14
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Hamster 小鼠 非结合性 FACS, IF, IHC, WB   500 μL Log in to see 33至42个工作日
¥5,834.11
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非结合性 IHC   50 μg Log in to see 33至42个工作日
¥6,396.87
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小鼠 非结合性 FACS, IHC, WB   100 μL Log in to see 33至42个工作日
¥6,396.87
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小鼠 非结合性 IC, FACS, IHC, WB   250 μg Log in to see 33至42个工作日
¥7,124.46
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大鼠 非结合性 IC, FACS, IHC, WB   125 μg Log in to see 33至42个工作日
¥7,330.37
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通过反应活性、应用领域、克隆类型和共轭标记 ABCB1B 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B 抗体

  1. Human Polyclonal ABCB1B Primary Antibody for FACS, IF (p) - ABIN670161 : Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. in Journal of experimental & clinical cancer research : CR 2009 (PubMed)
    Show all 2 references for ABIN670161

更多抗ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B的相互作用对抗体

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. Results find that ABCB1 (显示 ABCB1 抗体) is a target of miR (显示 MLXIP 抗体)-9 and reverses the effect of miR (显示 MLXIP 抗体)-9-mediated chemoresistance in K562 chronic myelogenous leukemia cells.

  2. findings suggest that osimertinib, a clinically-approved third-generation EGFR (显示 EGFR 抗体) TKI, can reverse ABCB1 (显示 ABCB1 抗体)-mediated MDR, which supports the combination therapy with osimertinib and ABCB1 (显示 ABCB1 抗体) substrates may potentially be a novel therapeutic stategy in ABCB1 (显示 ABCB1 抗体)-positive drug resistant cancers.

  3. Subcellular distribution of P-gp (显示 ABCB4 抗体) and subsequent downregulation by pristimerin contribute to overcoming ABCB1 (显示 ABCB1 抗体)-mediated chemotherapeutic drug resistance. Our findings suggested inducing the decrease of P-gp (显示 ABCB4 抗体) membrane protein could be a new promising alternative therapeutic strategy in ABCB1 (显示 ABCB1 抗体)-mediated Multidrug resistance.

  4. Rack1 (显示 GNB2L1 抗体) regulated P-Glycoprotein activity, which was necessary for adriamycin-induced P-Glycoprotein - mediated phosphorylation of Anxa2 (显示 ANXA2 抗体) and Erk1/2 (显示 MAPK1/3 抗体).

  5. we found that the C3435T MDR1 (显示 TBC1D9 抗体) polymorphism does not affect blood levels of cortisol or ACTH (显示 POMC 抗体) in healthy Japanese males. The effect size at alpha = 0.05 and at power 0.80 in the present sample size was 0.176 Thus, the present study suggests that the C3435T MDR1 (显示 TBC1D9 抗体) polymorphism does not have a great impact on blood levels of cortisol or ACTH (显示 POMC 抗体).

  6. ABCB1 (显示 ABCB1 抗体) 1236C/T variants might play a role in the risk of Parkinson's disease, whereas ABCB1 (显示 ABCB1 抗体) 3435C/T polymorphisms might not contribute to susceptibility to disease (Meta-Analysis)

  7. ABCB1 (显示 ABCB1 抗体) might play a pivotal role in acquisition of taxane resistance.

  8. A pro-apoptotic effect of verapamil was observed in L3.6pl cells, but not in L3.6plGres cells, which was linked to their differential expression of P-gp (显示 ABCB4 抗体) and equilibrative nucleoside transporter-1 (ENT-1 (显示 SLC29A1 抗体)).

  9. Our findings suggest that multidrug resistant osteosarcoma cells are able to spread their ability to resist the effects of doxorubicin treatment on sensitive cells by transferring exosomes carrying MDR-1 (显示 TBC1D9 抗体) mRNA and its product P-glycoprotein.

  10. Methylation of Notch3 (显示 NOTCH3 抗体) modulates chemoresistance via P-glycoprotein

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. Chrysosplenetin inhibited P-gp (显示 ABCB4 抗体) activity and reverse the up-regulated P-gp (显示 ABCB4 抗体) and MDR1 (显示 ABCB4 抗体) levels induced by artemisinin.

  2. Tamsulosin and tolterodine with P-gp (显示 ABCB4 抗体) gene expression and activity in an enantiomer-specific way.

  3. Pgp (显示 ABCB4 抗体)-coupled ATPase (显示 DNAH8 抗体) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  4. Data show that human transgenic mutant huntingtin (显示 HTT 抗体) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (显示 ABCB4 抗体)) which suggests that MDR1 (显示 ABCB4 抗体) might be a potential therapeutic target for Huntington's disease.

  5. In vitro and in vivo downregulation of the ATP binding cassette transporter (显示 ABCC3 抗体) B1 by the HMG-CoA reductase (显示 HMGCR 抗体) inhibitor simvastatin

  6. Efficient chemoprotection of CDD (显示 CDA 抗体) and MDR1 (显示 ABCB4 抗体) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (显示 FOXC1 抗体)-C and anthracycline application

  7. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1 (显示 ABCB1 抗体)-1Delta mutant mice following exposure to various P-gp (显示 ABCB4 抗体) substrates.

  8. Data indicate that the brain penetration of ABT-888 in both Abcb1a (显示 ABCB4 抗体)/1b-/- and Abcb1a (显示 ABCB4 抗体)/1b-/-;Abcg2 (显示 ABCG2 抗体)-/- mice was significantly higher than in wild-type mice.

  9. Expression of Abcb1 (显示 ABCB1 抗体) at the blood-brain and blood-spinal barriers is upregulated by Nrf2 (显示 NFE2L2 抗体).

  10. The improved structures of Pgp reveal important implications for polyspecific drug recognition in the form of a high concentration of aromatic residues in the drug translocation pathway that is most conserved among mammalian orthologs.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) 抗原简介

蛋白简介

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1B

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) 抗体
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) 抗体
  • ABC20 抗体
  • Abcb1 抗体
  • CD243 抗体
  • CLCS 抗体
  • GP170 抗体
  • mdr 抗体
  • Mdr1 抗体
  • Mdr1b 抗体
  • P-GP 抗体
  • Pgy-1 抗体
  • Pgy1 抗体

Protein level used designations for ABCB1B

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1

GENE ID SPECIES
5243 Homo sapiens
18669 Mus musculus
24646 Rattus norvegicus
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