anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) 抗体

The membrane-associated protein encoded by ABCB1B is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B 蛋白 (11)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ABCB1B 5243 P08183
ABCB1B 18669 P06795
ABCB1B 24646  

antibodies-online.cn销售最多的anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B 抗体

Showing 10 out of 31 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody (ABIN670161), Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody , Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 5至7个工作日
¥2,709.56
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非结合性 ICC, IF, IHC (p) Immunofluorescence analysis of mouse kidney tissue using anti-MDR1 (dilution of primary antibody - 1:1000) Immunohistochemical staining of paraffin embedded mouse kidney tissue using anti-MDR1 (primary antibody at 1:1000) 100 μg Log in to see 29至38个工作日
¥3,117.66
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小鼠 非结合性 IF, IP, WB   100 μL Log in to see 34至38个工作日
¥2,807.65
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小鼠 非结合性 FACS, IF, IHC, WB   500 μL Log in to see 33至42个工作日
¥6,067.47
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小鼠 非结合性 IC, IHC, WB   100 μg Log in to see 33至42个工作日
¥4,571.14
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Hamster 小鼠 非结合性 FACS, IF, IHC, WB   500 μL Log in to see 33至42个工作日
¥5,834.11
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非结合性 IHC   50 μg Log in to see 33至42个工作日
¥6,396.87
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小鼠 非结合性 FACS, IHC, WB   100 μL Log in to see 33至42个工作日
¥6,396.87
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小鼠 非结合性 IC, FACS, IHC, WB   250 μg Log in to see 33至42个工作日
¥7,124.46
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大鼠 非结合性 IC, FACS, IHC, WB   125 μg Log in to see 33至42个工作日
¥7,330.37
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通过反应活性、应用领域、克隆类型和共轭标记 ABCB1B 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B 抗体

  1. Human Polyclonal ABCB1B Primary Antibody for FACS, IF (p) - ABIN670161 : Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. in Journal of experimental & clinical cancer research : CR 2009 (PubMed)
    Show all 2 references for 670161

更多抗ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B的相互作用对抗体

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. A subset of virus-specific CD161 (显示 KLRB1 抗体)(+) T cells selectively express the multidrug transporter MDR1 (显示 TBC1D9 抗体) and are resistant to chemotherapy in acute myeloid leukemia (显示 BCL11A 抗体).

  2. Primary CD4 (显示 CD4 抗体)+P-gphigh T cells eliminate intracellular raltegravir more readily than P-gplow cells and HIV-1 viraemia correlates with P-gp (显示 ABCB4 抗体) overall activity; specific CD4 (显示 CD4 抗体)+P-gphigh T cell subsets could facilitate the persistence of viral replication in vivo and ultimately promote the appearance of drug resistance

  3. We observed an association between ABCB1 (显示 ABCB1 抗体) 3435 T/T and lower grade of toxicities (p=0.05) in patients receiving taxanes for breast cancer. No other associations were found for CYP (显示 PPIG 抗体) 3A4 *1B, 3A5*3 and ABCB1 (显示 ABCB1 抗体) C1236T.

  4. that residual SWI (显示 SMARCA1 抗体)/SNF (显示 SNRPA 抗体) complexes lacking SMARCB1 (显示 SMARCB1 抗体) are vital determinants of drug sensitivity, not just to TOP2A (显示 TOP2A 抗体)-targeted agents, but to the much broader range of cancer drugs effluxed by ABCB1 (显示 ABCB1 抗体).

  5. Patients with active rheumatoid arthritis have an increased function of ABCB1 (显示 ABCB1 抗体) and ABCG2 (显示 ABCG2 抗体), and disease activity is the main determinant of this phenomena.

  6. the induction of P-gp (显示 ABCB4 抗体) expression is causally associated with the expression of nestin (显示 NES 抗体) in leukemia cells

  7. High MDR1 (显示 TBC1D9 抗体) expression is associated with Cisplatin Resistance in Gastric Cancer.

  8. overexpression is a key Initiator of resistance to tyrosine kinase (显示 TXK 抗体) inhibitors in chronic myeloid leukemia (显示 BCL11A 抗体) cell lines

  9. The results indicate that human BCRP (显示 ABCG2 抗体) and not human P-gp (显示 ABCB4 抗体) is involved in benzylpenicillin transport.

  10. Study suggests thatSNPs of 1236C > T contributed to an individual variation in anesthetic effects that follow the pediatric tonsillectomy, and also it was figured out that the patients with the MDR1 1236C > T CC genotype displayed superior anesthetic effects compared to those patients who possessed the CT + TT genotype

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (显示 ABCB4 抗体) ATPase (显示 DNAH8 抗体) activity

  2. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  3. Chrysosplenetin inhibited P-gp (显示 ABCB4 抗体) activity and reverse the up-regulated P-gp (显示 ABCB4 抗体) and MDR1 (显示 ABCB4 抗体) levels induced by artemisinin.

  4. Tamsulosin and tolterodine with P-gp (显示 ABCB4 抗体) gene expression and activity in an enantiomer-specific way.

  5. Pgp (显示 ABCB4 抗体)-coupled ATPase (显示 DNAH8 抗体) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  6. Data show that human transgenic mutant huntingtin (显示 HTT 抗体) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (显示 ABCB4 抗体)) which suggests that MDR1 (显示 ABCB4 抗体) might be a potential therapeutic target for Huntington's disease.

  7. In vitro and in vivo downregulation of the ATP binding cassette transporter (显示 ABCC3 抗体) B1 by the HMG-CoA reductase (显示 HMGCR 抗体) inhibitor simvastatin

  8. Efficient chemoprotection of CDD (显示 CDA 抗体) and MDR1 (显示 ABCB4 抗体) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (显示 FOXC1 抗体)-C and anthracycline application

  9. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1 (显示 ABCB1 抗体)-1Delta mutant mice following exposure to various P-gp (显示 ABCB4 抗体) substrates.

  10. Data indicate that the brain penetration of ABT-888 in both Abcb1a (显示 ABCB4 抗体)/1b-/- and Abcb1a (显示 ABCB4 抗体)/1b-/-;Abcg2 (显示 ABCG2 抗体)-/- mice was significantly higher than in wild-type mice.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) 抗原简介

蛋白简介

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1B

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) 抗体
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) 抗体
  • ABC20 抗体
  • Abcb1 抗体
  • CD243 抗体
  • CLCS 抗体
  • GP170 抗体
  • mdr 抗体
  • Mdr1 抗体
  • Mdr1b 抗体
  • P-GP 抗体
  • Pgy-1 抗体
  • Pgy1 抗体

Protein level used designations for ABCB1B

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1

GENE ID SPECIES
5243 Homo sapiens
18669 Mus musculus
24646 Rattus norvegicus
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