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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) 抗体

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 试剂盒 (16)ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795

antibodies-online.cn销售最多的anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 抗体

Showing 10 out of 241 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 EIA, WB 0.1 mg Log in to see 29至35个工作日
¥3,632.23
详细
非结合性 ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. 25 μL Log in to see 23至28个工作日
¥3,357.01
详细
小鼠 非结合性 BP, ICC, IF, IHC, IHC (p), IP, Neut, WB Western Blot: MDR1/ABCB1 Antibody (C219) [ABIN153083] - Analysis of MDR1 in OSW canine lymphoma cell line using anti-MDR1 antibody. Image from verified customer review. Immunohistochemistry-Paraffin: MDR1/ABCB1 Antibody (C219) [ABIN153083] - Staining of formalin fixed paraffin embedded human liver tissue. 0.25 mL Log in to see 25至31个工作日
¥3,119.56
详细
小鼠 非结合性 IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 29至35个工作日
¥3,783.60
详细
小鼠 非结合性 ELISA, WB 0.1 mg Log in to see 24至29个工作日
¥10,808.99
详细
小鼠 非结合性 FACS, IHC (fro), IF, IHC (p), IP   0.1 mg Log in to see 29至35个工作日
¥3,279.08
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小鼠 PE FACS   100 Tests Log in to see 29至35个工作日
¥5,095.23
详细
非结合性 IHC, WB WB Suggested Anti-ABCB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: NCI-H226 cell lysate 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Log in to see 26至32个工作日
¥2,560.58
详细
非结合性 IHC, IHC (p) Immunohistochemistry: MDR1/ABCB1 Antibody [NBP1-90291] - Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
详细

通过反应活性、应用领域、克隆类型和共轭标记 ABCB1 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 抗体

  1. Dog (Canine) Monoclonal ABCB1 Primary Antibody for BP, ICC - ABIN153083 : van Den Elsen, Kuntz, Hoedemaeker, Rose: Antibody C219 recognizes an alpha-helical epitope on P-glycoprotein. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 11 references for ABIN153083

  2. Dog (Canine) Polyclonal ABCB1 Primary Antibody for EIA, WB - ABIN401371 : Baker, Johnstone, Zalcberg, El-Osta: Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs. in Oncogene 2005 (PubMed)
    Show all 6 references for ABIN401371

  3. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN317070 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... in Cancer research 1996 (PubMed)
    Show all 2 references for ABIN317070

  4. Human Polyclonal ABCB1 Primary Antibody for IHC, IHC (p) - ABIN4333368 : Bernstein, Hölzl, Dobrowolny, Hildebrandt, Trübner, Krohn, Bogerts, Pahnke: Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. in Mechanisms of ageing and development 2015 (PubMed)
    Show all 2 references for ABIN4333368

  5. Human Monoclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1724927 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. in Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 references for ABIN1724927

  6. Human Monoclonal ABCB1 Primary Antibody for IHC (fro), IF - ABIN1106124 : Callen, Baker, Simmers, Seshadri, Roninson: Localization of the human multiple drug resistance gene, MDR1, to 7q21.1. in Human genetics 1987 (PubMed)
    Show all 2 references for ABIN1106124

  7. Human Monoclonal ABCB1 Primary Antibody for FACS, IHC (fro) - ABIN317069 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)

  8. Human Polyclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1043891 : Al-Shawi, Omote: The remarkable transport mechanism of P-glycoprotein: a multidrug transporter. in Journal of bioenergetics and biomembranes 2006 (PubMed)

更多抗ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1的相互作用对抗体

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (显示 ABCB4 抗体), Bcrp (显示 ABCG2 抗体) and Mrp1 (显示 ABCC1 抗体) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Study investigated the effect of MDR1 (显示 TBC1D9 抗体), CYP2D6 (显示 CYP2D6 抗体) and CYP2C19 (显示 CYP2C19 抗体) gene polymorphisms on prophylactic therapy response in migraine patients, suggested that migraine patients who receive topiramate prophylactic treatment should be assessed for the presence of the MDR1 (显示 TBC1D9 抗体) C3435T polymorphism

  2. The GG and TT genotypes in CYP3A5 (显示 CYP3A5 抗体)*3 and ABCB1 C3435T, respectively, were linked with higher TPC (显示 CCDC6 抗体).

  3. The study revealed the correlation between ABCB1 DNA promoter methylation with rs1128503 and rs2032582 polymorphisms in malaria and was related to increased expression of ABCB1 protein levels in complicated malaria group when compared to uncomplicated malaria and control groups.

  4. findings suggest that Tetrandrine prevents paclitaxel-induced MDR by inhibiting Pgp (显示 PGPEP1 抗体) overexpression through a mechanism that may involve the inhibition of NF-kappaB (显示 NFKB1 抗体) signaling in osteosarcoma.

  5. Results find that ABCB1 is a target of miR (显示 MLXIP 抗体)-9 and reverses the effect of miR (显示 MLXIP 抗体)-9-mediated chemoresistance in K562 chronic myelogenous leukemia cells.

  6. findings suggest that osimertinib, a clinically-approved third-generation EGFR (显示 EGFR 抗体) TKI, can reverse ABCB1-mediated MDR, which supports the combination therapy with osimertinib and ABCB1 substrates may potentially be a novel therapeutic stategy in ABCB1-positive drug resistant cancers.

  7. Subcellular distribution of P-gp (显示 ABCB4 抗体) and subsequent downregulation by pristimerin contribute to overcoming ABCB1-mediated chemotherapeutic drug resistance. Our findings suggested inducing the decrease of P-gp (显示 ABCB4 抗体) membrane protein could be a new promising alternative therapeutic strategy in ABCB1-mediated Multidrug resistance.

  8. Rack1 (显示 GNB2L1 抗体) regulated P-Glycoprotein activity, which was necessary for adriamycin-induced P-Glycoprotein - mediated phosphorylation of Anxa2 (显示 ANXA2 抗体) and Erk1/2 (显示 MAPK1/3 抗体).

  9. we found that the C3435T MDR1 (显示 TBC1D9 抗体) polymorphism does not affect blood levels of cortisol or ACTH (显示 POMC 抗体) in healthy Japanese males. The effect size at alpha = 0.05 and at power 0.80 in the present sample size was 0.176 Thus, the present study suggests that the C3435T MDR1 (显示 TBC1D9 抗体) polymorphism does not have a great impact on blood levels of cortisol or ACTH (显示 POMC 抗体).

  10. ABCB1 1236C/T variants might play a role in the risk of Parkinson's disease, whereas ABCB1 3435C/T polymorphisms might not contribute to susceptibility to disease (Meta-Analysis)

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Chrysosplenetin inhibited P-gp (显示 ABCB4 抗体) activity and reverse the up-regulated P-gp (显示 ABCB4 抗体) and MDR1 (显示 ABCB4 抗体) levels induced by artemisinin.

  2. Tamsulosin and tolterodine with P-gp (显示 ABCB4 抗体) gene expression and activity in an enantiomer-specific way.

  3. Pgp (显示 ABCB4 抗体)-coupled ATPase (显示 DNAH8 抗体) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  4. Data show that human transgenic mutant huntingtin (显示 HTT 抗体) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (显示 ABCB4 抗体)) which suggests that MDR1 (显示 ABCB4 抗体) might be a potential therapeutic target for Huntington's disease.

  5. In vitro and in vivo downregulation of the ATP binding cassette transporter (显示 ABCC3 抗体) B1 by the HMG-CoA reductase (显示 HMGCR 抗体) inhibitor simvastatin

  6. Efficient chemoprotection of CDD (显示 CDA 抗体) and MDR1 (显示 ABCB4 抗体) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (显示 FOXC1 抗体)-C and anthracycline application

  7. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp (显示 ABCB4 抗体) substrates.

  8. Data indicate that the brain penetration of ABT-888 in both Abcb1a (显示 ABCB4 抗体)/1b-/- and Abcb1a (显示 ABCB4 抗体)/1b-/-;Abcg2 (显示 ABCG2 抗体)-/- mice was significantly higher than in wild-type mice.

  9. Expression of Abcb1 at the blood-brain and blood-spinal barriers is upregulated by Nrf2 (显示 NFE2L2 抗体).

  10. The improved structures of Pgp reveal important implications for polyspecific drug recognition in the form of a high concentration of aromatic residues in the drug translocation pathway that is most conserved among mammalian orthologs.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) 抗原简介

蛋白简介

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (abcb1) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) 抗体
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) 抗体
  • malic enzyme complex, mitochondrial (Mod2) 抗体
  • ABC20 抗体
  • ABCB1 抗体
  • Cd243 抗体
  • CLCS 抗体
  • GP170 抗体
  • Mdr 抗体
  • Mdr-1 抗体
  • Mdr1 抗体
  • Mdr1a 抗体
  • Mdr1b 抗体
  • Mod-2 抗体
  • Mod-2r 抗体
  • Mod-2s 抗体
  • Mod2-r 抗体
  • Mod2-s 抗体
  • p-gp 抗体
  • PGP1 抗体
  • Pgy-1 抗体
  • Pgy1 抗体
  • xemdr 抗体

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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