anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) 抗体

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 试剂盒 (20)ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795

antibodies-online.cn销售最多的anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 抗体

Showing 10 out of 279 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB <b>WB Suggested Anti-ABCB1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>NCI-H226 cell lysate 100 μL Log in to see 5至7个工作日
¥20,898.73
详细
非结合性 ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. 25 μL Log in to see 23至28个工作日
¥3,357.01
详细
非结合性 IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Log in to see 26至32个工作日
¥2,560.58
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非结合性 EIA, WB   0.1 mg Log in to see 30至37个工作日
¥3,358.40
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小鼠 非结合性 IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 29至35个工作日
¥3,783.60
详细
小鼠 非结合性 ELISA, WB 0.1 mg Log in to see 24至29个工作日
¥10,808.99
详细
小鼠 非结合性 IHC (p), WB Human Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 29至35个工作日
¥4,324.07
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非结合性 IHC (p) Anti-ABCB1 / MDR1 antibody  ABIN1048283 IHC staining of human kidney, proximal convoluted tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 29至35个工作日
¥4,324.07
详细
Hamster 非结合性 IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 29至35个工作日
¥6,705.77
详细
小鼠 非结合性 FACS, IHC (fro), IF, IHC (p), IP   0.1 mg Log in to see 29至35个工作日
¥3,279.08
详细

通过反应活性、应用领域、克隆类型和共轭标记 ABCB1 抗体

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引用最多的anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 抗体

  1. Human Monoclonal ABCB1 Primary Antibody for ICC, IHC (fro) - ABIN3043101 : Gao, Liu, Wang, Lin, Zhang: Effects of Lewis Y antigen on the gene expression of multiple drug resistance-associated proteins in human ovarian cancer RMG-I-H cells. in Medical oncology (Northwood, London, England) 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal ABCB1 Primary Antibody for IHC (fro), FACS - ABIN2479419 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN2479421 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... in Cancer research 1996 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN2479422 : Koziolek, Riess, Geiger, Thévenod, Hauser: Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients. in Kidney international 2001 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN2479424 : Park, Lomri, Simeoni, Fruehauf, Mechetner: Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay. in Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1724927 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. in Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1724923 : Rubi?, Ho?ysz, Barczak, Gryczka, ?aci?ski, Jagielski, Czernikiewicz, Pó?rolniczak, Wojewoda, Perz, Bia?ek, Morze, Kandu?a, Lisiak, Mrozikiewicz, Grodecka-Gazdecka, Rybczy?ska: Study of ABCB1 polymorphism frequency in breast cancer patients from Poland. in Pharmacological reports : PR 2013 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal ABCB1 Primary Antibody for IHC, IHC (p) - ABIN4333368 : Bernstein, Hölzl, Dobrowolny, Hildebrandt, Trübner, Krohn, Bogerts, Pahnke: Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. in Mechanisms of ageing and development 2015 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal ABCB1 Primary Antibody for IHC (fro), IHC (p) - ABIN3043967 : Wang, Deng, Lu, Xu, Yan, Ye, Chen et al.: Gambogic acid as a non-competitive inhibitor of ATP-binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-binding cassette transporter B1 ... in Basic & clinical pharmacology & toxicology 2012 (PubMed)
    Show all 2 Pubmed References

  10. Human Polyclonal ABCB1 Primary Antibody for IHC (p) - ABIN2479425 : Marzolini, Paus, Buclin, Kim: Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance. in Clinical pharmacology and therapeutics 2004 (PubMed)

更多抗ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1的相互作用对抗体

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (显示 ABCB4 抗体), Bcrp (显示 ABCG2 抗体) and Mrp1 (显示 ABCC1 抗体) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. our findings demonstrated that MDR1 (显示 TBC1D9 抗体) expression is regulated by CDX2 (显示 CDX2 抗体) and is related to drug resistance in ovarian mucinous adenocarcinoma.

  2. Compared with the sensitive group, both mdr1 (显示 TBC1D9 抗体) mRNA and P-gp (显示 ABCB4 抗体) expressions increased in the resistant group

  3. an SNP in ABCB1 (rs2032582: 2677G > T/A) was significantly associated with atorvastatin-induced liver injury (AILI) indicating that the G allele might be a risk factor for AILI in Japanese population

  4. impact of CYP4F2 (显示 CYP4F2 抗体), ABCB1, and GGCX (显示 GGCX 抗体) polymorphisms on bleeding episodes associated with acenocoumarol in Russian patients with atrial fibrillation

  5. Collectively, the data establish a hitherto unknown liaison among MDR1 (显示 TBC1D9 抗体), BMI1 (显示 BMI1 抗体) and TIP60 (显示 KAT5 抗体) and provide mechanistic insights into cisplatin-induced MDR1 (显示 TBC1D9 抗体) expression resulting in acquired cross-resistance against paclitaxel, doxorubicin and likely other anticancer drugs.

  6. High ABCB1 expression is associated with hepatocellular carcinoma.

  7. Our data suggest that the C1236T and G2677A/T SNPs in the MDR1 (显示 TBC1D9 抗体) gene are associated with Crohn's disease and the C1236T risk allele with a more severe course of disease in Algerian pediatric patients.

  8. ATPase (显示 DNAH8 抗体) measurements imply that DCV and Ho are similarly handled by ABCB1, whereas ABCG2 (显示 ABCG2 抗体) seems to transport DVC more effectively. In addition, we have developed an image-based high content microscopy screening method for simultaneous in situ measurement of the cellular activity and expression of the ABCG2 (显示 ABCG2 抗体) multidrug transporter

  9. These results show that multidrug resistant leukemia cell microparticle regulation of ABCC1 (显示 ABCC1 抗体) in recipient cells is governed by the transfer of both miR (显示 MLXIP 抗体)-326 and ABCB1 from donor cells

  10. he modulatory effect of acacetin-doxorubicin combination on doxorubicin influx and efflux was mediated through downregulation of MDR1 (显示 TBC1D9 抗体) treansporter in non-small-cell lung carcinoma (NSCLC) cells.

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Loss of ABCB1 expression is associated with neonatal hyperbilirubinemia.

  2. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (显示 ABCB4 抗体) ATPase (显示 DNAH8 抗体) activity

  3. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  4. Chrysosplenetin inhibited P-gp (显示 ABCB4 抗体) activity and reverse the up-regulated P-gp (显示 ABCB4 抗体) and MDR1 (显示 ABCB4 抗体) levels induced by artemisinin.

  5. Tamsulosin and tolterodine with P-gp (显示 ABCB4 抗体) gene expression and activity in an enantiomer-specific way.

  6. Pgp (显示 ABCB4 抗体)-coupled ATPase (显示 DNAH8 抗体) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  7. Data show that human transgenic mutant huntingtin (显示 HTT 抗体) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (显示 ABCB4 抗体)) which suggests that MDR1 (显示 ABCB4 抗体) might be a potential therapeutic target for Huntington's disease.

  8. In vitro and in vivo downregulation of the ATP binding cassette transporter (显示 ABCC3 抗体) B1 by the HMG-CoA reductase (显示 HMGCR 抗体) inhibitor simvastatin

  9. Efficient chemoprotection of CDD (显示 CDA 抗体) and MDR1 (显示 ABCB4 抗体) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (显示 FOXC1 抗体)-C and anthracycline application

  10. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp (显示 ABCB4 抗体) substrates.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) 抗原简介

蛋白简介

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (abcb1) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) 抗体
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) 抗体
  • malic enzyme complex, mitochondrial (Mod2) 抗体
  • ABC20 抗体
  • ABCB1 抗体
  • Cd243 抗体
  • CLCS 抗体
  • GP170 抗体
  • Mdr 抗体
  • Mdr-1 抗体
  • Mdr1 抗体
  • Mdr1a 抗体
  • Mdr1b 抗体
  • Mod-2 抗体
  • Mod-2r 抗体
  • Mod-2s 抗体
  • Mod2-r 抗体
  • Mod2-s 抗体
  • p-gp 抗体
  • PGP1 抗体
  • Pgy-1 抗体
  • Pgy1 抗体
  • xemdr 抗体

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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