anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) 抗体

The protein encoded by ABCA7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发ABCA7 试剂盒 (14)ABCA7 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ABCA7 27403 Q91V24
ABCA7 10347 Q8IZY2
ABCA7 299609 Q7TNJ2
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antibodies-online.cn销售最多的anti-ABCA7 抗体

Showing 10 out of 77 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 EIA, IF, WB   0.1 mg Log in to see 12至15个工作日
$375.38
详细
小鼠 大鼠 非结合性 FACS, IHC (p), WB Flow Cytometry: ABCA7 Antibody (7A1-144) [ABIN438226] - Analysis using Azide/BSA FREE version of ABIN438226. Analysis of 6C (red) (negative control HeLa cells) and A7(blue) (ABCA7 expressing HeLa cells) using NB 400-166 at a dilution of 1:3,000. Western Blot: ABCA7 Antibody (7A1-144) [ABIN438226] - Detection of ABCA7 using NB 400-163 at various dilutions in ABCA7 transfected HeLa lysates. 0.1 mL Log in to see 7至9个工作日
$408.19
详细
非结合性 WB Western blot analysis of ABCA7 expression in HeLa (A), Raw264.7 (B), mouse liver (C), PC12 (D) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
小鼠 大鼠 非结合性 FACS   0.25 mg Log in to see 6至8个工作日
$346.50
详细
小鼠 大鼠 PE FACS   100 Tests Log in to see 7至9个工作日
$390.50
详细
非结合性 WB Abca7 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg Log in to see 6至8个工作日
$473.93
详细
小鼠 非结合性 WB Western Blot: ABCA7 Antibody [NBP1-69064] - Titration: 0.2-1 ug/ml, Positive Control: Mouse Liver. 100 μL Log in to see 7至9个工作日
$408.19
详细
非结合性 ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: ABCA7 Antibody [NBP2-14250] Staining of human cell line A-431 shows positivity in plasma membrane and golgi apparatus. Immunohistochemistry-Paraffin: ABCA7 Antibody [NBP2-14250] - Staining of human bone marrow shows strong cytoplasmic positivity in hematopoietic cells. 0.1 mL Log in to see 10至13个工作日
$439.69
详细
小鼠 大鼠 非结合性 FACS, WB   100 μL Log in to see 11至16个工作日
$592.43
详细

通过反应活性、应用领域、克隆类型和共轭标记 ABCA7 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine) , , ,
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Rat (Rattus) , , ,


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引用最多的anti-ABCA7 抗体

  1. Cow (Bovine) Polyclonal ABCA7 Primary Antibody for WB - ABIN2781526 : Bamji-Mirza, Li, Najem, Liu, Walker, Lue, Stupak, Chan, Li, Ghani, Yang, Rogaeva, Zhang: Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-β40 and Amyloid-β42 Peptides and ABCA7 Transcription in Cell Culture Models. in Journal of Alzheimer's disease : JAD 2016 (PubMed)

更多抗ABCA7的相互作用对抗体

Mouse (Murine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) interaction partners

  1. ABCA7 does not play a significant role in the regulation of cell proliferation or neurogenesis in the adult mouse.

  2. This study demonstrated that novel mechanism underlying how dysfunctions of ABCA7 contribute to the risk for alzheimer disease.

  3. ABCA7 has a role in Alzheimer amyloid processing

  4. Theresults of this study suggested that ABCA7 plays a role in the regulation of Abeta (显示 APP 抗体) homeostasis in the brain and that this may be related to altered phagocyte function.

  5. ABCA7 may play a role in T cell proliferation and erythropoeisis in spleen

  6. concluded that statins enhance macrophage phagocytosis through the SREBP-ABCA7 pathway.

  7. Data suggest that extracellular helical apolipoproteins augment ABCA7-associated phagocytosis by stabilizing ABCA7, and show direct enhancement of the host defense system by HDL (显示 HSD11B1 抗体) components.

  8. ABCA7 has the ability to bind apolipoproteins and promote efflux of cellular phospholipids without cholesterol, and has a possible role of ABCA7 in cellular phospholipid metabolism in peripheral tissues

  9. genetic knockdown of ABCA7 in mouse peritoneal macrophages did not affect phospholipid or cholesterol efflux to apoA-I (显示 APOA1 抗体)

  10. ABCA7 plays a novel role in lipid and fat metabolism

Human ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) interaction partners

  1. The major difference in the pattern of lipid peaks between ABCA7 and ABCA1 (显示 ABCA1 抗体) was the high lysoPC/PC ratio of ABCA7.

  2. Results confirm that ABCA7 loss of function variants are enriched in patients with Alzheimer disease and extend this finding to predicted damaging missense variants

  3. A detailed clinicopathologic description of patients carrying an ABCA7 loss of function mutation: a classical Alzheimer disease phenotype, though with a striking wide onset age range, suggesting the influence of unknown modifying factors

  4. Results suggested that ABCA7 genotypes contribute to the AD risk through involvement in amyloid-beta deposition on in vivo imaging, but not in tau pathology, brain atrophy, or decreased glucose metabolism

  5. Common variants in ABCA7 and MS4A6A (显示 MS4A6A 抗体) are associated with cortical and hippocampal atrophy.

  6. Studies indicate that ATP-binding cassette transporter (显示 ABCA4 抗体) A7 (ABCA7) single nucleotide polymorphisms (SNPs) that increase Alzheimer's disease (AD) risk.

  7. Study replicates the association of ABCA7 loss-of-function variants with Alzheimer's disease risk, and highlights the necessity of performing gene-based, rather than single-variant analyses to replicate the association in this type of studies

  8. ABCA7 has a role in Alzheimer amyloid processing

  9. The results are consistent with the view that assembly of HDL particles with extracellular apoA-I is primarily with the cellular phospholipid molecules being regulated in part by their physicochemical nature.

  10. Loss-of-function of ABCA7 could be a potential mechanism of Alzheimer's disease as shown in a Belgian cohort.

ABCA7 抗原简介

蛋白简介

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known\; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system.

Gene names and symbols associated with ABCA7

  • ATP binding cassette subfamily A member 7 (ABCA7) 抗体
  • ATP-binding cassette sub-family A member 7 (LOC468639) 抗体
  • ATP-binding cassette sub-family A member 7 (LOC100088822) 抗体
  • ATP-binding cassette, sub-family A (ABC1), member 7 (Abca7) 抗体
  • ATP binding cassette subfamily A member 7 (Abca7) 抗体
  • Abc51 抗体
  • ABCA-SSN 抗体
  • ABCA7 抗体
  • ABCX 抗体

Protein level used designations for ABCA7

ATP-binding cassette sub-family A member 7 , ATP-binding cassette, sub-family A, member 7 , ATP-binding cassette, sub-family A (ABC1), member 7 , autoantigen SS-N , macrophage ABC transporter

GENE ID SPECIES
511762 Bos taurus
455538 Pan troglodytes
468639 Pan troglodytes
485090 Canis lupus familiaris
704976 Macaca mulatta
100088822 Ornithorhynchus anatinus
100623892 Sus scrofa
27403 Mus musculus
10347 Homo sapiens
299609 Rattus norvegicus
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