anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 12 (ABCA12) 抗体

The membrane-associated protein encoded by ABCA12 is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发ABCA12 试剂盒 (1)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ABCA12 26154 Q86UK0
ABCA12 74591  
ABCA12 301482  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • 在线下订单
  • orders@antibodies-online.cn

antibodies-online.cn销售最多的anti-ABCA12 抗体

Showing 10 out of 37 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
$289.00
详细
山羊 非结合性 ICC, IF, IP, ELISA   0.1 mg Log in to see 7至9个工作日
$317.63
详细
非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 IF (p), IHC (p) Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-ABCA12 Polyclonal Antibody, Unconjugated (ABIN1386605) at 1:200 followed by conjugation to the secondary antibody and DAB staining Paraformaldehyde-fixed, paraffin embedded rat testis, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with ABCA12 Polyclonal Antibody, Unconjugated  at 1:600 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining 100 μL Log in to see 3至7个工作日
$295.90
详细
Alexa Fluor 594 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细
Cy5.5 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细
Cy7 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细
HRP IHC (p)   100 μL Log in to see 14至21个工作日
$405.90
详细
Cy5 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细
Alexa Fluor 350 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细

通过反应活性、应用领域、克隆类型和共轭标记 ABCA12 抗体

特性 应用范围 宿主 克隆类型 标记
Human , , ,
,

, , , , , , , , , , , , , , , ,
Mouse (Murine) , , ,
,

, , , , , , , , , , , , ,
Rat (Rattus) , ,


, , , , , , , , , , , , ,

引用最多的anti-ABCA12 抗体

  1. Human Polyclonal ABCA12 Primary Antibody for ICC, IF - ABIN408721 : Sakai, Akiyama, Sugiyama-Nakagiri, McMillan, Sawamura, Shimizu: Localization of ABCA12 from Golgi apparatus to lamellar granules in human upper epidermal keratinocytes. in Experimental dermatology 2007 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal ABCA12 Primary Antibody for WB - ABIN2781522 : Hlavá?, Brynychová, Václavíková, Ehrlichová, Vrána, Pecha, Koževnikovová, Trnková, Gat?k, Kopperová, Gut, Sou?ek: The expression profile of ATP-binding cassette transporter genes in breast carcinoma. in Pharmacogenomics 2013 (PubMed)

更多抗ABCA12的相互作用对抗体

Zebrafish ATP-Binding Cassette, Sub-Family A (ABC1), Member 12 (ABCA12) interaction partners

  1. The morphological findings are akin to epidermal changes in harlequin ichthyosis (显示 CST6 抗体) and CEDNIK (显示 SNAP29 抗体) syndrome, autosomal recessive keratinization disorders due to mutations in the ABCA12 and SNAP29 (显示 SNAP29 抗体) genes, respectively.

Human ATP-Binding Cassette, Sub-Family A (ABC1), Member 12 (ABCA12) interaction partners

  1. we identified three novel mutations and one reported mutation in the TGM1 (显示 TGM1 抗体) and ABCA12 genes, respectively, in affected siblings of five Saudi unrelated families

  2. Genes ABCC7 (显示 CFTR 抗体), A3, A8, A12 (显示 UGT1A9 抗体), and C8 prevailed among the most upregulated or downregulated ones. In conclusion, the results supported our theory about general adenosine triphosphate-binding cassette gene expression profiles and their importance for cancer on clinical as well as research levels.

  3. Autosomal recessive inheritance of mutations in the ATP-binding cassette, subfamily A (显示 CYP 抗体), member 12 (ABCA12, OMIM*607800, chromosome 2q35) gene was found to be responsible for the disease.

  4. Identification of the key promoter element of ABCA12 in this study may provide relevant information for genetic diagnosis of recessive congenital ichthyosis (显示 LBR 抗体).

  5. Ssnger sequencing of the parents of neonates deceased patients with Harlequin ichthyosis (显示 CST6 抗体) identified novel mutations in ABCA12 gene.

  6. ABCA12 mutations result in defective lipid transport via lamellar granules in the keratinocytes, leading to ichthyosis (显示 LBR 抗体) phenotypes from malformation of the stratum corneum lipid barrier.

  7. Report a consanguineous family of Arab Muslim origin with several members displaying a severe form of congenital ichthyosiform erythroderma. Identified a region of homozygosity shared by all patients on 2q34, in a region harbouring the ABCA12 gene.

  8. We show that homozygosity for a novel c.4676G>T transition in the ABCA12 gene, resulting in a p.G1559V substitution, causes non-bullous congenital ichthyosiform erythroderms in 5 members of an extended family.

  9. The authors report on a 2282del4 mutation that may be associated with ichthyosis (显示 LBR 抗体) vulgaris in a Pakistani population.

  10. The researchers report on another fatal case of Harlequin ichthyosis (显示 CST6 抗体) that may be associated with mutations of the ABCA12 gene

Mouse (Murine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 12 (ABCA12) interaction partners

  1. these findings suggest an essential role for ABCA12 in transferring not only lipids, which are required for the formation of multilamellar structures in the stratum corneum, but also proteolytic enzymes that are required for normal desquamation.

  2. Data indicate that ABC transporter A family member 12 knockout (Abca12(-/-)) epidermis had 5-fold more beta-glucocerebrosidase (GCase (显示 GBA 抗体)) protein, and a 5-fold increase in GCase (显示 GBA 抗体) activity.

  3. ABCA12 mutations result in defective lipid transport via lamellar granules in the keratinocytes, leading to ichthyosis (显示 LBR 抗体) phenotypes from malformation of the stratum corneum lipid barrier.

  4. ABCA12 regulates the cellular cholesterol metabolism via an LXRbeta (显示 NR1H2 抗体)-dependent posttranscriptional mechanism.

  5. Results indicate that disrupted keratinocyte differentiation during the fetal development is involved in the pathomechanism of HI and, during maturation, Abca12(-/-) epidermal keratinocytes regain normal differentiation processes.

  6. ABCA12 plays pivotal roles in lung and skin barrier functions in Harlequin ichthyosis (显示 CST6 抗体) disease midel.

  7. Abca12 is a regulator of lipid transport and homeostasis.

  8. ABCA12 activity is required for the generation of long-chain ceramide esters that are essential for the development of normal skin structure and function

ABCA12 抗原简介

蛋白简介

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with ABCA12

  • ATP binding cassette subfamily A member 12 (ABCA12) 抗体
  • ATP-binding cassette, sub-family A (ABC1), member 12 (abca12) 抗体
  • ATP-binding cassette, sub-family A (ABC1), member 12 (Abca12) 抗体
  • ATP binding cassette subfamily A member 12 (Abca12) 抗体
  • 4832428G11Rik 抗体
  • 4833417A11Rik 抗体
  • ARCI4A 抗体
  • ARCI4B 抗体
  • cb352 抗体
  • ICR2B 抗体
  • LI2 抗体
  • sb:cb352 抗体

Protein level used designations for ABCA12

ATP-binding cassette, sub-family A (ABC1), member 12 , ATP-binding cassette, sub-family A, member 12 , ATP-binding cassette sub-family A member 12 , ATP-binding cassette sub-family A member 12-like , ATP-binding cassette transporter 12

GENE ID SPECIES
424011 Gallus gallus
459924 Pan troglodytes
523479 Bos taurus
558335 Danio rerio
694427 Macaca mulatta
100341171 Oryctolagus cuniculus
100464882 Ailuropoda melanoleuca
26154 Homo sapiens
478900 Canis lupus familiaris
100512445 Sus scrofa
74591 Mus musculus
301482 Rattus norvegicus
anti-ABCA12 (ABCA12) 抗体 精选生产商
您还需要查找其他产品吗?