anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) 抗体

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 试剂盒 (21)ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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antibodies-online.cn销售最多的anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 抗体

Showing 10 out of 280 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB <b>WB Suggested Anti-ABCB1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>NCI-H226 cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. 25 μL Log in to see 1至2个工作日
$139.00
详细
非结合性 IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Log in to see 4至6个工作日
$240.00
详细
非结合性 EIA, WB   0.1 mg Log in to see 12至15个工作日
$636.30
详细
小鼠 非结合性 ELISA, WB 100 μg Log in to see 2至3个工作日
$430.10
详细
小鼠 非结合性 IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 6至8个工作日
$313.50
详细
小鼠 非结合性 IHC (p), WB Human Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 7至9个工作日
$484.00
详细
非结合性 IHC (p) Anti-ABCB1 / MDR1 antibody  ABIN1048283 IHC staining of human kidney, proximal convoluted tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7至9个工作日
$484.00
详细
Hamster 非结合性 IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7至9个工作日
$727.83
详细
小鼠 非结合性 FACS, IHC (fro), IF, IHC (p), IP   0.1 mg Log in to see 6至8个工作日
$346.50
详细

通过反应活性、应用领域、克隆类型和共轭标记 ABCB1 抗体

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引用最多的anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 抗体

  1. Human Polyclonal ABCB1 Primary Antibody for IHC, IHC (p) - ABIN4333368 : Bernstein, Hölzl, Dobrowolny, Hildebrandt, Trübner, Krohn, Bogerts, Pahnke: Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. in Mechanisms of ageing and development 2015 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1724923 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. in Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1724927 : Rubi?, Ho?ysz, Barczak, Gryczka, ?aci?ski, Jagielski, Czernikiewicz, Pó?rolniczak, Wojewoda, Perz, Bia?ek, Morze, Kandu?a, Lisiak, Mrozikiewicz, Grodecka-Gazdecka, Rybczy?ska: Study of ABCB1 polymorphism frequency in breast cancer patients from Poland. in Pharmacological reports : PR 2013 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal ABCB1 Primary Antibody for IHC (fro), FACS - ABIN2479419 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN2479421 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... in Cancer research 1996 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN2479422 : Koziolek, Riess, Geiger, Thévenod, Hauser: Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients. in Kidney international 2001 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN2479424 : Park, Lomri, Simeoni, Fruehauf, Mechetner: Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay. in Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003 (PubMed)
    Show all 4 Pubmed References

  8. Human Polyclonal ABCB1 Primary Antibody for IHC (fro), IHC (p) - ABIN3043967 : Gao, Liu, Wang, Lin, Zhang: Effects of Lewis Y antigen on the gene expression of multiple drug resistance-associated proteins in human ovarian cancer RMG-I-H cells. in Medical oncology (Northwood, London, England) 2010 (PubMed)
    Show all 2 Pubmed References

  9. Human Monoclonal ABCB1 Primary Antibody for ICC, IHC (fro) - ABIN3043101 : Wang, Deng, Lu, Xu, Yan, Ye, Chen et al.: Gambogic acid as a non-competitive inhibitor of ATP-binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-binding cassette transporter B1 ... in Basic & clinical pharmacology & toxicology 2012 (PubMed)
    Show all 2 Pubmed References

  10. Hamster Monoclonal ABCB1 Primary Antibody for FACS, ICC - ABIN4333365 : Kurihara, Sato, Akimoto, Ogura, Ito: Identification and characterization of ABCB1-mediated and non-apoptotic sebum secretion in differentiated hamster sebocytes. in Biochimica et biophysica acta 2011 (PubMed)

更多抗ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1的相互作用对抗体

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (显示 ABCB4 抗体), Bcrp (显示 ABCG2 抗体) and Mrp1 (显示 ABCC1 抗体) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Results show that CD133 and MDR1 (显示 TBC1D9 抗体) expression increase in recurrent pediatric pilocytic astrocytomas (PAs (显示 PASK 抗体)) following chemotherapy, and in drug resistant tumor cells. CD133 regulates MDR1 (显示 TBC1D9 抗体) expression via the PI3K (显示 PIK3CA 抗体)/AKT (显示 AKT1 抗体)/NF-kappaB (显示 NFKB1 抗体) signaling. These results provide evidence that CD133 contributes to multidrug resistance by regulating MDR1 (显示 TBC1D9 抗体) levels via the PI3K (显示 PIK3CA 抗体)-Akt (显示 AKT1 抗体)-NF-kappaB (显示 NFKB1 抗体) signal pathway.

  2. PG accumulation assay is a new, unique tool for the parallel determination of the function of the ABCG2 (显示 ABCG2 抗体), ABCB1, and ABCC1 (显示 ABCC1 抗体) multidrug transporters

  3. Abcb1a/b(-/-);Abcg2 (显示 ABCG2 抗体)(-/-) mice revealed increased brain penetration of rapamycin (13-fold), AZD8055 (7.7-fold), and NVP-BEZ235 (4.5-fold), but not ZSTK474 relative to WT mice. Importantly, ABC (显示 ABCB6 抗体) transporters limited rapamycin brain penetration to subtherapeutic levels, while the reduction in NVP-BEZ235 brain penetration did not prevent target inhibition.

  4. ABCB1 genotype is not a significant determinant of interindividual variability in dabigatran and rivaroxaban pharmacokinetics

  5. High MDR1 (显示 TBC1D9 抗体) expression is associated with multidrug resistance in breast cancer.

  6. inhibition of autophagy led to the decrease in stemness, restoration of mitochondrial proteins and reduced expression of CD44 (显示 CD44 抗体), ABCB1 and ADAM17 (显示 ADAM17 抗体)

  7. The T-allele of ABCB1-C3435T gene polymorphism has demonstrated to be a good prognosis factor for resistance, progression free survival and overall survival in HER2 (显示 ERBB2 抗体)-positive Breast Cancer patients.

  8. we review the emerging role of molecular dynamics simulation techniques in our understanding of the membrane-embedded conformation of P-gp (显示 ABCB4 抗体)--{REVIEW}

  9. Studied ABCB1 protein expression immunohistochemically in twelve human post-mortem brain regions known to play a role in schizophrenia, in 13 patients with schizophrenia and nine controls; found a significantly reduced density of ABCB1-expressing neurons in the left habenula.

  10. Using an integrated pathway-based approach, we identified polymorphisms in ABCC6 (显示 ABCC6 抗体), ABCB1 and CYP2C8 (显示 CYP2C8 抗体) associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Molecular Dynamics simulations and docking of drugs performed for P-gp (P-gp (显示 ABCB4 抗体), multi-drug resistance protein, MDR1 (显示 ABCB4 抗体)).Drugs with ER < 1 (显示 MIER1 抗体) almost do not bind the main binding cavity (MBC (显示 CACNA1C 抗体)) of P-gp (显示 ABCB4 抗体).

  2. conclusion, MDR1 (显示 ABCB4 抗体) and BCRP (显示 ABCG2 抗体) are expressed on apical membranes of the rodent placental SynT (显示 STX1A 抗体)-II layer.

  3. Mdr1 (显示 ABCB4 抗体) enforces T Cell homeostasis in the presence of intestinal bile acids.

  4. Loss of ABCB1 expression is associated with neonatal hyperbilirubinemia.

  5. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (显示 ABCB4 抗体) ATPase (显示 DNAH8 抗体) activity

  6. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  7. Chrysosplenetin inhibited P-gp (显示 ABCB4 抗体) activity and reverse the up-regulated P-gp (显示 ABCB4 抗体) and MDR1 (显示 ABCB4 抗体) levels induced by artemisinin.

  8. Tamsulosin and tolterodine with P-gp (显示 ABCB4 抗体) gene expression and activity in an enantiomer-specific way.

  9. Pgp (显示 ABCB4 抗体)-coupled ATPase (显示 DNAH8 抗体) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  10. Data show that human transgenic mutant huntingtin (显示 HTT 抗体) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (显示 ABCB4 抗体)) which suggests that MDR1 (显示 ABCB4 抗体) might be a potential therapeutic target for Huntington's disease.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) 抗原简介

蛋白简介

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP binding cassette subfamily B member 1 (ABCB1) 抗体
  • ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) 抗体
  • ATP binding cassette subfamily B member 1A (Abcb1a) 抗体
  • ATP binding cassette subfamily B member 1 (Abcb1) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) 抗体
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) 抗体
  • malic enzyme complex, mitochondrial (Mod2) 抗体
  • ABC20 抗体
  • ABCB1 抗体
  • Cd243 抗体
  • CLCS 抗体
  • GP170 抗体
  • Mdr 抗体
  • Mdr-1 抗体
  • Mdr1 抗体
  • Mdr1a 抗体
  • Mdr1b 抗体
  • Mod-2 抗体
  • Mod-2r 抗体
  • Mod-2s 抗体
  • Mod2-r 抗体
  • Mod2-s 抗体
  • p-gp 抗体
  • PGP1 抗体
  • Pgy-1 抗体
  • Pgy1 抗体
  • xemdr 抗体

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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