电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

ABCA4 抗体

(ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. [provided by RefSeq, Jul 2008].
ABCA4 抗体  (AA 2250-2263) ABCA4 抗体  (AA 2250-2263) ABCA4 抗体 (AA 2250-2263) (ABIN343052)

Verified ABCA4 适用: 人, 小鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated

ABCA4 抗体  (AA 1398-1727) ABCA4 抗体  (AA 1398-1727) ABCA4 抗体 (AA 1398-1727) (ABIN7441073)

ABCA4 适用: 人 WB, ELISA, IHC (fro), ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

ABCA4 抗体 ABCA4 抗体 ABCA4 抗体 (ABIN7238477)

ABCA4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

ABCA4 抗体 by Grade

Find ABCA4 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

ABCA4 抗体 by 适用

Find ABCA4 抗体 for a variety of species such as anti-Human ABCA4, anti-Mouse ABCA4, anti-Rat ABCA4. The species listed below are among those available. Click on a link to go to the corresponding products.

ABCA4 抗体 by 应用范围

Find ABCA4 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

ABCA4 抗体 by 抗体来源

Find ABCA4 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

ABCA4 抗体 by 抗原表位

Find ABCA4 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

ABCA4 抗体 by 克隆形成能力

Find available monoclonal or polyclonal ABCA4 抗体. Click on a link to go to the corresponding products.

ABCA4 抗体 by 克隆

Find ABCA4 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

ABCA4 抗体 by 标记

Find ABCA4 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular ABCA4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, IF
Validations
  • (3)
  • (4)
Cat. No. ABIN343052
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (fro), ICC, IHC (p)
Validations
  • (2)
Cat. No. ABIN7441073
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7238477
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN559734
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN6259677
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow
Application WB, IHC
Validations
  • (1)
Cat. No. ABIN361347
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
Cat. No. ABIN6389221
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF
Validations
Cat. No. ABIN7111807
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN335106
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB
Validations
Cat. No. ABIN2613672
Quantity 100 μg
Datasheet Datasheet
Reactivity Bat, Guinea Pig, Mouse, Rabbit, Rat
Application WB
Validations
Cat. No. ABIN2613673
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN5518717
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN7300302
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN5647438
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow
Application WB, ELISA, IHC
Validations
Cat. No. ABIN6655047
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our ABCA4 抗体

McClements, Barnard, Issa, MacLaren: "Assessment of AAV Dual Vector Safety in theAbca4-/- Mouse Model of Stargardt Disease." in: Translational vision science & technology, Vol. 9, Issue 7, pp. 20, (2020) (PubMed).

Mäkeläinen, Gòdia, Hellsand, Viluma, Hahn, Makdoumi, Zeiss, Mellersh, Ricketts, Narfström, Hallböök, Ekesten, Andersson, Bergström: "An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease." in: PLoS genetics, Vol. 15, Issue 3, pp. e1007873, (2019) (PubMed).

McClements, Barnard, Singh, Charbel Issa, Jiang, Radu, MacLaren: "An AAV Dual Vector Strategy Ameliorates the Stargardt Phenotype in Adult Abca4-/- Mice." in: Human gene therapy, Vol. 30, Issue 5, pp. 590-600, (2019) (PubMed).

Lenis, Hu, Ng, Jiang, Sarfare, Lloyd, Esposito, Samuel, Jaworski, Bok, Finnemann, Radeke, Redmond, Travis, Radu: "Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 47, pp. E11120-E11127, (2019) (PubMed).

Allocca, Doria, Petrillo, Colella, Garcia-Hoyos, Gibbs, Kim, Maguire, Rex, Di Vicino, Cutillo, Sparrow, Williams, Bennett, Auricchio: "Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice." in: The Journal of clinical investigation, Vol. 118, Issue 5, pp. 1955-64, (2008) (PubMed).

Singh, Jalali, Hejtmancik, Kannabiran: "Homozygous null mutations in the ABCA4 gene in two families with autosomal recessive retinal dystrophy." in: American journal of ophthalmology, Vol. 141, Issue 5, pp. 906-13, (2006) (PubMed).

Wiszniewski, Zaremba, Yatsenko, Jamrich, Wensel, Lewis, Lupski: "ABCA4 mutations causing mislocalization are found frequently in patients with severe retinal dystrophies." in: Human molecular genetics, Vol. 14, Issue 19, pp. 2769-78, (2005) (PubMed).

Illing, Molday, Molday: "The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily." in: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10303-10, (1997) (PubMed).

Aliases for ABCA4 抗体

ATP binding cassette subfamily A member 4 (ABCA4) 抗体
ATP-binding cassette, sub-family A (ABC1), member 4 (Abca4) 抗体
ATP binding cassette subfamily A member 4 (Abca4) 抗体
ATP binding cassette subfamily A member 4 (abca4) 抗体
ATP binding cassette subfamily A member 4 L homeolog (abca4.L) 抗体
ATP-binding cassette, sub-family A (ABC1), member 4a (abca4a) 抗体
ABC10 抗体
Abc10 抗体
abc10 抗体
ABCR 抗体
Abcr 抗体
abcr 抗体
ARMD2 抗体
armd2 抗体
AW050280 抗体
CORD3 抗体
cord3 抗体
D430003I15Rik 抗体
FFM 抗体
ffm 抗体
RMP 抗体
RmP 抗体
rmp 抗体
RP19 抗体
rp19 抗体
STGD 抗体
stgd 抗体
STGD1 抗体
stgd1 抗体
zgc:91823 抗体
You are here:
客服