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ACLY 蛋白

(ATP Citrate Lyase (ACLY))
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
ACLY Protein (AA 4-265) (His tag) ACLY Protein (AA 4-265) (His tag) ACLY Protein (AA 4-265) (His tag) (ABIN7121924)

ACLY 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

ACLY Protein (AA 1-1091) (His tag) ACLY Protein (AA 1-1091) (His tag) ACLY Protein (AA 1-1091) (His tag) (ABIN3136775)

Crystallography grade ACLY 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

ACLY Protein (AA 1-1101) (His tag) ACLY Protein (AA 1-1101) (His tag) ACLY Protein (AA 1-1101) (His tag) (ABIN3088222)

Crystallography grade ACLY 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

ACLY 蛋白 by Grade

Find ACLY 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

ACLY 蛋白 by Origin

Find ACLY 蛋白 for a variety of species such as anti-Human ACLY, anti-Mouse ACLY. The species listed below are among those available. Click on a link to go to the corresponding products.

ACLY 蛋白 by Source

Here you will find ACLY 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

ACLY 蛋白 by 蛋白类型

Here you can find ACLY 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

ACLY 蛋白 by 应用范围

Find ACLY 蛋白 validated for a specific application such as ELISA, WB, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular ACLY 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121924
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136775
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088222
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
Cat. No. ABIN7194322
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2715038
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our ACLY 蛋白

Chen, Qian, He, Zhao, Toral-Barza, Shi, Zhang, Wu, Yu: "mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer." in: Oncotarget, Vol. 7, Issue 18, pp. 25224-40, (2018) (PubMed).

Aliases for ACLY 蛋白

ATP citrate lyase (ACLY) 蛋白
ATP citrate lyase S homeolog (acly.S) 蛋白
ATP-citrate synthase (LOC587157) 蛋白
ATP citrate lyase (acly) 蛋白
ATP citrate lyase (ATPCL) 蛋白
ATP-citrate synthase (LOC5564509) 蛋白
citrate synthase, mitochondrial (CpipJ_CPIJ010291) 蛋白
ATP-citrate synthase (Bm1_26245) 蛋白
atp-citrate synthase (ACL) 蛋白
ATP citrate lyase (Acly) 蛋白
ATP citrate lyase a (aclya) 蛋白
A730098H14Rik 蛋白
ACL 蛋白
ACLY 蛋白
acly 蛋白
anon-WO0140519.179 蛋白
ATPCL 蛋白
AW538652 蛋白
BcDNA:LD21334 蛋白
cb722 蛋白
CG8322 蛋白
CLATP 蛋白
Clatp 蛋白
dATPCL 蛋白
DDBDRAFT_0205389 蛋白
DDBDRAFT_0235360 蛋白
DDB_0205389 蛋白
DDB_0235360 蛋白
DmATPCL 蛋白
Dmel\\CG8322 蛋白
l(2)01466 蛋白
l(2)k09217 蛋白
n(2)k09217 蛋白
zgc:92008 蛋白
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