anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) 抗体

ADAMTS4 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. 再加上,我们可以发ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 试剂盒 (42)ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 蛋白 (9)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ADAMTS4 240913 Q8BNJ2
ADAMTS4 9507 O75173
ADAMTS4 66015 Q9ESP7

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Showing 10 out of 166 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB WB Suggested Anti-ADAMTS4 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 EIA, WB Western blot analysis of anti-ADAMTS4 Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). ADAMTS4 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 29至35个工作日
¥4,086.26
详细
非结合性 WB Western blot analysis of anti-ADAMTS4 Antibody (C-term) (ABIN391642) in mouse cerebellum tissue lysates (35 µg/lane). ADAMTS4 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 5至8个工作日
¥2,325.14
详细
非结合性 WB Anti-ADAMTS4 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Mouse Brain Tissue Lysate 100 μg Log in to see 26至32个工作日
¥2,560.58
详细
Cow 非结合性 WB Host: RabbitTarget Name: Adamts4Antibody Dilution: 1.0ug/mlSample Tissue: Rat Kidney Host: Rabbit  Target Name: Adamts4  Antibody Dilution: 1.0 µg/mL  Sample Tissue: Rat Kidney 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-ADAMTS4 Polyclonal Antibody, Unconjugated (ABIN755173) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 5至7个工作日
¥2,610.23
详细
小鼠 非结合性 WB ADAMTS4 Polyclonal Antibody 0.1 mg Log in to see 29至35个工作日
¥3,783.60
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非结合性 ELISA, IHC (p), WB   100 μg Log in to see 26至32个工作日
¥2,919.96
详细
Alexa Fluor 350 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Alexa Fluor 488 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
详细

通过反应活性、应用领域、克隆类型和共轭标记 ADAMTS4 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 抗体

  1. Cow (Bovine) Polyclonal ADAMTS4 Primary Antibody for IHC, WB - ABIN2776877 : Lee, Hwang, Park, Lee, Park, Kang, Lee, Kim, Park, Park: Comparison of ADAMTS-1, -4 and -5 expression in culprit plaques between acute myocardial infarction and stable angina. in Journal of clinical pathology 2011 (PubMed)
    Show all 3 references for 2776877

  2. Human Polyclonal ADAMTS4 Primary Antibody for WB - ABIN391642 : Tortorella, Pratta, Liu, Abbaszade, Ross, Burn, Arner: The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 references for 391642

  3. Human Polyclonal ADAMTS4 Primary Antibody for EIA, WB - ABIN359602 : Tortorella, Burn, Pratta, Abbaszade, Hollis, Liu, Rosenfeld, Copeland, Decicco, Wynn, Rockwell, Yang, Duke, Solomon, George, Bruckner, Nagase, Itoh, Ellis, Ross, Wiswall, Murphy, Hillman, Hollis et al.: Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins. ... in Science (New York, N.Y.) 1999 (PubMed)
    Show all 2 references for 359602

更多抗ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4的相互作用对抗体

Rabbit ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. a single injection of ADAMTS5 (显示 ADAMTS5 抗体) siRNA induced the suppression of degradation in rabbit nucleus pulposus tissues

Horse (Equine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. Studies suggest that miR (显示 MYLIP 抗体)-140 is an important regulator of cartilage development and homeostasis in cord blood-derived mesenchymal stromal cells (eCB-MSCs) that may act, in part, through the regulation of CXCL12 (显示 CXCL12 抗体) and ADAMTS-5 (显示 ADAMTS5 抗体).

  2. ADAMTS5 (显示 ADAMTS5 抗体) is present in degenerative suspensory ligament desmitis as a high molecular weight complex

Cow (Bovine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. ADAMTS4 participates in the regulation of muscle development in cattle.

  2. aggrecanase activity (a) is responsible for early TNFalpha (显示 TNF 抗体)-dependent aggrecan (显示 ACAN 抗体) cleavage and GAG release in the meniscus and (b) might be involved in meniscal degeneration.

  3. ADAMTS4 and ADAMTS5 (显示 ADAMTS5 抗体) are inhibited by alpha2-macroglobulin (显示 A2M 抗体)

  4. identified multiple conserved amino acids within regions N- and C-terminal to the site of scission that may influence enzyme-substrate recognition, and may interact with exosites on ADAMTS-4 and ADAMTS-5 (显示 ADAMTS5 抗体)

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. the reduction of ADAMTS-4 activity during the progression of ALS pathology may be an adaptive change to mitigate its neurodegenerative impact in CNS tissues

  2. Results show that ADAMTS15 (显示 ADAMTS15 抗体) and ADAMTS4 not only exhibit unique cellular expression patterns in the brain but their developmental upregulation by these cell types coincides with critical aspects of neural development

  3. aggrecan (显示 ACAN 抗体) and brevican (显示 BCAN 抗体) proteolysis is compensated in Adamts4-/- or Adamts5 (显示 ADAMTS5 抗体)-/- mice by ADAMTS (显示 ADAMTS1 抗体) proteoglycanase (显示 MMP3 抗体) family members but a threshold of versican (显示 Vcan 抗体) proteolysis is sensitive to the loss of a single ADAMTS (显示 ADAMTS1 抗体) proteoglycanase (显示 MMP3 抗体) during spinal cord injury

  4. ADAMTS4 has roles in melanoma growth and angiogenesis in mice

  5. The serine protease (显示 F2 抗体) tissue plasminogen activator (tPA (显示 PLAT 抗体)) and two matrix metalloproteinases, ADAMTS-4 and ADAMTS-5 (显示 ADAMTS5 抗体), were identified as Reelin (显示 RELN 抗体) cleaving enzymes.

  6. ADAMTS-4 cleaves Reelin (显示 RELN 抗体) in an isoform-specific manner. Among ADAMTS-4 isoforms, p50 (显示 LSP1 抗体) cleaves the N-t site only, while p75 (显示 NGFR 抗体) cleaves both sites.

  7. Data demonstrate that Adamts1 (显示 ADAMTS1 抗体) and Adamts4 play redundant and essential roles in perinatal kidney development.

  8. Drastic down-regulation of Adamts4 observed at both E16 (显示 SLC7A5 抗体) and E18; RT-PCR revealed post-natal reduction in expression (Adamts4, 1/3). Results suggest down-regulation of gene is important factor in normal odontogenesis in dental papillae.

  9. proteolysis of hevin by ADAMTS4 in the mouse cerebellum is important for the normal development of this tissue

  10. ADAMTS1 (显示 ADAMTS1 抗体), ADAMTS4, and ADAMTS5 (显示 ADAMTS5 抗体) are expressed in patterns that relate to the expression pattern of versican (显示 Vcan 抗体) in granulosa cells of small follicles, expanded cumulus cell-oocyte complexes, and endothelial cells of the ovary.

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. Using in vitro approaches and cultured breast cancer cell lines authors demonstrate that Fibulin-2 (显示 FBLN2 抗体) is a better substrate for ADAMTS-5 (显示 ADAMTS5 抗体) than it is for ADAMTS-4. Fibulin-2 (显示 FBLN2 抗体) degradation is associated to an enhancement of the invasive potential of T47D, MCF-7 and SK-BR-3 cells.

  2. ADAMTS4 and ADAMTS15 (显示 ADAMTS15 抗体) were upregulated in symptomatic uterine leiomyomas.

  3. The SNP rs4233367 in the exon of ADAMTS-4 gene may be associated with lumbar disc degeneration.

  4. Single Nucleotide Variants of Candidate Genes in Aggrecan (显示 ACAN 抗体) Metabolic Pathway Are Associated with Lumbar Disc Degeneration and Modic Changes

  5. Results show that ADAMTS4 mRNA is the target of mir (显示 MLXIP 抗体)-1268a and its expression might be modified by MIR (显示 MLXIP 抗体)-1268a rs28599926 polymorphism in hepatocellular carcinoma.

  6. we investigated whether important polymorphisms in the ADAMTS4 and ADAMTS5 (显示 ADAMTS5 抗体) genes affect osteoarthritis (OA) susceptibility. ADAMTS4 and ADAMTS5 (显示 ADAMTS5 抗体) genotypes were determined using the ABI Prism StepOnePlus Real-Time system. Our findings suggest that the ADAMTS4 (rs4233367 and rs11807350) and ADAMTS5 (显示 ADAMTS5 抗体) (rs226794 and rs2830585) variants examined may not contribute to susceptibility to knee OA in the Turkish population.

  7. ADAMTS4 expression is significantly upregulated in human masticatory mucosa during wound healing

  8. ADAMTS4 may have a role in the pathogenesis by causing increased oxidative and inflammatory environment in preterm premature rupture of membranes .

  9. in degenerative intervertebral discs, IL1b (显示 IL1B 抗体) upregulates NFkB, MMP13 (显示 MMP13 抗体) and ADAMTS4

  10. progesterone acts via the progesterone receptor (显示 PGR 抗体) to modulate ADAMTS 1 (显示 ADAMTS1 抗体) and 4 levels in ovarian cancer cell lines.

ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) 抗原简介

蛋白简介

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues.

Gene names and symbols associated with ADAMTS4

  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 (Adamts4) 抗体
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4) 抗体
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13) 抗体
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5) 抗体
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) (ADAMTS5) 抗体
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4 (Adamts4) 抗体
  • ADAM metallopeptidase with thrombospondin type 1 motif, 19 (Adamts19) 抗体
  • ADAM metallopeptidase with thrombospondin type 1 motif, 19 (ADAMTS19) 抗体
  • ADAM metallopeptidase with thrombospondin type 1 motif, 3 (ADAMTS3) 抗体
  • aggrecanase-1 (ADAMTS-4) 抗体
  • ADAMTS-like 4 (ADAMTSL4) 抗体
  • 3830423K05 抗体
  • ADAM-TS4 抗体
  • ADAMTS-2 抗体
  • ADAMTS-4 抗体
  • ADAMTS-11 抗体
  • ADAMTS4 抗体
  • ADAMTS5 抗体
  • ADAMTS13 抗体
  • ADMP-1 抗体
  • DKFZp469J0817 抗体
  • mKIAA0688 抗体

Protein level used designations for ADAMTS4

A disintegrin and metalloproteinase with thrombospondin motifs 4 , ADAM-TS 4 , ADAMTS-4 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4 , aggrecanase-1 , ADAM-TS4 , ADAM metallopeptidase with thrombospondin type 1 motif, 13 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13 , ADAM metallopeptidase with thrombospondin type 1 motif, 5 , ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) , aggrecanase-2 , Aggrecanase , a disintegrin and metallopeptidase with thrombospondin motifs 4 , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 , ADMP-1 , ADAM metallopeptidase with thrombospondin type 1 motif, 4 , A disintegrin and metalloproteinase with thrombospondin motifs 4-like , A disintegrin and metalloproteinase with thrombospondin motifs 19 , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19 , ADAM metallopeptidase with thrombospondin type 1 motif, 19 , ADAM metallopeptidase with thrombospondin type 1 motif, 19-like , A disintegrin and metalloproteinase with thrombospondin motifs 3 , ADAM-TS 3 , ADAM-TS3 , ADAMTS-3 , PC II-NP , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3 , procollagen II N-proteinase , procollagen II amino propeptide-processing enzyme , zinc metalloendopeptidase , disintegrin and metalloproteinase with thrombospondin motifs 2

GENE ID SPECIES
240913 Mus musculus
9507 Homo sapiens
417152 Gallus gallus
473153 Pan troglodytes
487713 Canis lupus familiaris
427971 Gallus gallus
100066005 Equus caballus
100008799 Oryctolagus cuniculus
707672 Macaca mulatta
473935 Pan troglodytes
66015 Rattus norvegicus
286806 Bos taurus
457453 Pan troglodytes
488651 Canis lupus familiaris
719927 Macaca mulatta
100033914 Equus caballus
100171426 Pongo abelii
100409334 Callithrix jacchus
361332 Rattus norvegicus
415600 Gallus gallus
462039 Pan troglodytes
537961 Bos taurus
705362 Macaca mulatta
9508 Homo sapiens
100008765 Oryctolagus cuniculus
100482466 Ailuropoda melanoleuca
100606067 Nomascus leucogenys
100514576 Sus scrofa
100712995 Cavia porcellus
101106565 Ovis aries
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