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anti-ADAM Metallopeptidase Domain 15 (ADAM15) 抗体

The protein encoded by ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. 再加上,我们可以发ADAM15 试剂盒 (16)ADAM15 蛋白 (13)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ADAM15 11490 O88839
ADAM15 8751 Q13444
ADAM15 57025 Q9QYV0

antibodies-online.cn销售最多的anti-ADAM15 抗体

Showing 10 out of 94 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB WB Suggested Anti-ADAM15 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human brain 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
小鼠 非结合性 FACS, ICC, IHC, IP, WB ADAM15 in MCF-7 Human Cell Line. ADAM15 was detected in immersion fixed MCF-7 human breast cancer cell line using Human ADAM15 Ectodomain Monoclonal Antibody. ADAM15 in Human Prostate Cancer Tissue. ADAM15 was detected in immersion fixed paraffin-embedded sections of human prostate cancer tissue using 25 ug/mL Human ADAM15 Ectodomain Monoclonal Antibody. 100 μg Log in to see 26至31个工作日
¥2,401.31
详细
小鼠 PE FACS Profile of anti-ADAM15 reactivity on MCF-7 cells analyzed by flow cytometry. ADAM15 Antibody (APC), Mouse MAb, Flow cytometric analysis 50 Tests Log in to see 14至15个工作日
¥1,929.62
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PE FACS Profile of anti-ADAM15 reactivity on MCF-7 cells analyzed by flow cytometry. ADAM15 Antibody (APC), Rabbit MAb, Flow cytometric analysis 50 Tests Log in to see 14至15个工作日
¥1,929.62
详细
Cow 非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
详细
小鼠 非结合性 FACS, ELISA 100 μg Log in to see 14至15个工作日
¥2,144.03
详细
小鼠 PE FACS Detection of ADAM15 in MCF-7 Human Cell Line by Flow Cytometry. MCF-7 human breast cancer cell line was stained with Mouse Anti-Human ADAM15 Ectodomain PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 26至31个工作日
¥2,615.71
详细
小鼠 APC FACS 50 Tests Log in to see 14至15个工作日
¥1,929.62
详细
APC FACS 50 Tests Log in to see 14至15个工作日
¥1,929.62
详细
小鼠 FITC FACS 50 Tests Log in to see 14至15个工作日
¥1,929.62
详细

通过反应活性、应用领域、克隆类型和共轭标记 ADAM15 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine) ,
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Human , , , ,
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Rat (Rattus) ,


引用最多的anti-ADAM15 抗体

  1. Human Monoclonal ADAM15 Primary Antibody for FACS, ICC - ABIN4900519 : Ungerer, Doberstein, Bürger, Hardt, Boehncke, Böhm, Pfeilschifter, Dummer, Mihic-Probst, Gutwein: ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 3 references for ABIN4900519

  2. Cow (Bovine) Polyclonal ADAM15 Primary Antibody for IHC, WB - ABIN2782601 : Zhong, Poghosyan, Pennington, Scott, Handsley, Warn, Gavrilovic, Honert, Krüger, Span, Sweep, Edwards: Distinct functions of natural ADAM-15 cytoplasmic domain variants in human mammary carcinoma. in Molecular cancer research : MCR 2008 (PubMed)

更多抗ADAM15的相互作用对抗体

Rabbit ADAM Metallopeptidase Domain 15 (ADAM15) interaction partners

  1. ADAM15 attenuates the progression of atherosclerosis; in contrast, a mutated form of ADAM15, created by ablation of the protease function, has no significant effect on atherosclerosis.

Mouse (Murine) ADAM Metallopeptidase Domain 15 (ADAM15) interaction partners

  1. findings indicated that silencing ADAM15 had antiinflammatory effects in FLSs and efficiently inhibited the development of CIA (显示 NCOA5 抗体).

  2. the catalytic activity of ADAM15 is not crucial for its function in promoting pathological neovascularization in the mouse OIR model, most likely because of the very limited substrate repertoire of ADAM15.

  3. ADAM15 upregulation contributes to inflammatory lung injury by promoting endothelial hyperpermeability and neutrophil transmigration.

  4. A disintegrin and metalloproteinase 15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src (显示 SRC 抗体) family kinase activity.

  5. Adult Adam15(-/-) mice displayed an increase in bone volume and thickness with an increase in the number and activity of osteoblasts, whereas osteoclasts were apparently unaffected.

  6. ADAM15 has a role in pathological neovascularization in mice

  7. cytoplasmic domain of ADAM15v2 strongly interacts with Lck (显示 LCK 抗体) and plays an important role in T lymphocytes

  8. The accelerated development of murine osteoarthritis in ADAM15 deficiency and the proadhesive and cell survival-promoting in vitro effect of ADAM15 overexpression suggest a homeostatic role of ADAM15 in cartilage remodeling.

  9. observations suggest that a disintegrin and metalloproteinase (ADAM)-8 (显示 ADAM8 抗体),-9,-10,-12,-15,and -17 play an important role in mouse uterine tissue remodelling during the oestrous cycle

  10. found modest expression of ADAM15 in pericytes in normal retina and strong up-regulation of ADAM15 in retinal vascular endothelial cells in ischemic retina

Human ADAM Metallopeptidase Domain 15 (ADAM15) interaction partners

  1. Data show that ADAM9 (显示 ADAM9 抗体) silencing affected MMP2 (显示 MMP2 抗体) and ADAM15 expression.

  2. ADAM15 promotes lung cancer cell invasion through directly targeting MMP9 (显示 MMP9 抗体) activation.

  3. the results revealed an undescribed role of ADAM15 in the invasion of human bladder cancer and suggested that the ADAM15 catalytic domain may represent a viable therapeutic target in patients with advanced disease.

  4. present a tumor suppressive mechanism for ADAM15 exosomes and provide insight into the functional significance of exosomes that generate tumor-inhibitory factors

  5. these data suggest the potential role of miR147b in regulating endothelial barrier function by targeting ADAM15 expression.

  6. findings indicated that silencing ADAM15 had antiinflammatory effects in FLSs and efficiently inhibited the development of CIA (显示 ASF1A 抗体).

  7. The severity of intrauterine adhesions positively correlates to the protein and transcript expression levels of ADAM-15 and ADAM-17 (显示 ADAM17 抗体) in uterine tissue.

  8. ADAM15 contributes to apoptosis resistance in rheumatoid arthritis synovial fibroblasts by activating the Src (显示 SRC 抗体)/FAK (显示 PTK2 抗体) pathway upon FasL (显示 FASL 抗体) exposure.

  9. ADAM15 acts as a negative regulator of TRIF (显示 TRIM69 抗体)-mediated NF-kappaB (显示 NFKB1 抗体) and IFN-beta (显示 IFNB1 抗体) reporter gene activity via TLR3 (显示 TLR3 抗体) and TLR4 (显示 TLR4 抗体) signaling.

  10. Exosomes rich in ADAM15 display enhanced binding affinity for integrin alphavbeta3 (显示 ITGAV 抗体) in an RGD-dependent manner and suppress vitronectin (显示 VTN 抗体)- and fibronectin (显示 FN1 抗体)-induced cell adhesion, growth, and migration, as well as in vivo tumor growth.

ADAM15 抗原简介

蛋白简介

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with ADAM15

  • ADAM metallopeptidase domain 15 (ADAM15) 抗体
  • ADAM metallopeptidase domain 15 (adam15) 抗体
  • a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15) 抗体
  • ADAM metallopeptidase domain 15 (Adam15) 抗体
  • ADAM15 抗体
  • MDC15 抗体
  • metargidin 抗体
  • tMDCVI 抗体

Protein level used designations for ADAM15

ADAM metallopeptidase domain 15 , a disintegrin and metalloproteinase domain 15 , metalloproteinase ADAM15 , disintegrin and metalloproteinase domain-containing protein 15-like , AD56 , ADAM 15 , MDC-15 , a disintegrin and metalloprotease domain 15 (metargidin) , a disintegrin and metalloproteinase domain 15 (metargidin) , disintegrin and metalloprotease 15 , disintegrin and metalloproteinase domain-containing protein 15 , metalloprotease RGD disintegrin protein , metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15 , CRII-7 , a disintegrin and metallopeptidase domain 15 (metargidin) , metargidin , tMDC VI

GENE ID SPECIES
457354 Pan troglodytes
490434 Canis lupus familiaris
100101326 Xenopus laevis
100145641 Xenopus (Silurana) tropicalis
100339079 Oryctolagus cuniculus
100393011 Callithrix jacchus
100468507 Ailuropoda melanoleuca
11490 Mus musculus
8751 Homo sapiens
784605 Bos taurus
57025 Rattus norvegicus
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